{"hash":"1725618740730184303","title":"Pigmentation and Melanosome Assembly","description":"Based on the Top Terms, pigmentation (GO:0043473) and melanosome assembly (GO:1903232) are explicitly represented, suggesting the cluster's proteins function in pigment synthesis/transport and melanosome biogenesis. Additional enrichment in vesicle trafficking from the ER to the Golgi (GO:0006888) and regulation of GTPase activity (GO:0043547) supports a theme of organelle transport and localization related to pigment-containing organelles. Other terms such as cuticle development and stress or apoptotic responses may reflect broader cellular roles but are less central. Overall, the cluster appears to center on pigment-related processes, especially melanosome assembly, with some related trafficking activity.","confidence":"Medium","size":21,"edges":156,"triangles":604,"max_degree":19,"top_function":null,"members":[{"accession":"XP_002935038.3","go_terms":["GO:0090502","GO:0006388","GO:0000379"]},{"accession":"XP_002936462.1","go_terms":["GO:0043248"]},{"accession":"XP_002936950.1","go_terms":["GO:0006388"]},{"accession":"XP_031753282.1","go_terms":["GO:1905765","GO:0000012","GO:0021766","GO:0061819","GO:0002124"]},{"accession":"NP_001004844.1","go_terms":["GO:0000147","GO:0034314","GO:0030041"]},{"accession":"NP_001005073.1","go_terms":["GO:0007250","GO:0000338","GO:0043161","GO:0006446","GO:0060625","GO:1903955","GO:0010387","GO:0043248","GO:0001731"]},{"accession":"NP_001032339.1","go_terms":[]},{"accession":"NP_001072397.1","go_terms":["GO:0042797","GO:0001023","GO:0061484","GO:0008380","GO:0006915","GO:0001172","GO:0060213","GO:0010590","GO:0000291","GO:0097394","GO:0042254","GO:0006367","GO:0045948","GO:0042790"]},{"accession":"NP_001011085.1","go_terms":["GO:1904263","GO:0000492","GO:2000617","GO:2000619","GO:0071169","GO:0070286","GO:0060285","GO:0090240","GO:1901838","GO:0051569","GO:0048254","GO:1900113","GO:1900110","GO:1902661","GO:2001268"]},{"accession":"NP_001096457.1","go_terms":["GO:0048312","GO:0055059"]},{"accession":"NP_001005455.1","go_terms":["GO:1902043","GO:0048715","GO:0048712","GO:0048147","GO:0043525","GO:0021510","GO:0061535","GO:0061534","GO:0022011","GO:0021764","GO:0048485","GO:2001136","GO:0035023","GO:0021915","GO:0048169","GO:0098597","GO:0030325","GO:0008625","GO:0043547","GO:0045762","GO:0040009","GO:0001824","GO:0048820","GO:2001241","GO:2000212","GO:0042066","GO:0048593","GO:0048745","GO:0046929","GO:0001656","GO:0007406","GO:0021897","GO:1900271","GO:0001953","GO:0048853","GO:0032228","GO:0045671","GO:0070444","GO:0035021","GO:0090212","GO:0031322","GO:0007040","GO:0051452","GO:0051180","GO:0009636","GO:0043001","GO:2001247","GO:2001246","GO:0060548","GO:0007584","GO:0043942","GO:1901352","GO:0009268","GO:0001892","GO:0001890","GO:0046909","GO:0042360","GO:0010570","GO:2000114"]},{"accession":"XP_002933024.2","go_terms":["GO:0051123","GO:0010689","GO:1990141","GO:0010691","GO:0006351"]},{"accession":"XP_031754992.1","go_terms":[]},{"accession":"NP_001015955.1","go_terms":["GO:0000821","GO:0045059","GO:0002262","GO:0009846","GO:0097062","GO:0006525","GO:0035726","GO:0010183","GO:0032957","GO:0046854","GO:0001841","GO:0032958","GO:0010919","GO:0033030"]},{"accession":"XP_002938755.1","go_terms":["GO:0006368","GO:0043966","GO:0043967"]},{"accession":"NP_001037879.1","go_terms":["GO:0035753","GO:1900264","GO:0006260","GO:0007049","GO:0007064"]},{"accession":"XP_031758513.1","go_terms":["GO:0048208","GO:0043473","GO:0006891","GO:0006888","GO:0043547","GO:0006914","GO:0042338","GO:1903232"]},{"accession":"XP_002938070.1","go_terms":["GO:0048313","GO:0006623","GO:0048490","GO:0042147","GO:0006888","GO:0051645","GO:1901998","GO:0006896","GO:0043473","GO:0006890","GO:0006897","GO:0016185","GO:0009615","GO:0008344","GO:0021691"]},{"accession":"XP_031752204.1","go_terms":["GO:0018149","GO:0002839","GO:0060009","GO:2000504","GO:0008584","GO:0042747","GO:0030502","GO:0050766","GO:0032355","GO:0008544","GO:0007431","GO:0001666","GO:0009636","GO:0008344","GO:0033629","GO:0043067","GO:0045740","GO:0008284","GO:0030216","GO:0060548","GO:0070301","GO:0070268","GO:0048678","GO:0006953","GO:0001654","GO:0060311","GO:0060313","GO:0010951","GO:2001027","GO:0009743","GO:0010593","GO:0007420","GO:0010716","GO:0007566","GO:0042493","GO:0031667","GO:0010711","GO:1900747","GO:0006915","GO:0007339","GO:0030195"]},{"accession":"XP_031758514.1","go_terms":["GO:0048208","GO:0043473","GO:0006891","GO:0006888","GO:0043547","GO:0006914","GO:0042338","GO:1903232"]},{"accession":"NP_001004942.1","go_terms":[]}],"graph":[["NP_001096457.1","NP_001005073.1",0.67],["NP_001096457.1","NP_001005455.1",0.735],["NP_001096457.1","NP_001011085.1",0.722],["NP_001096457.1","NP_001032339.1",0.533],["NP_001096457.1","NP_001037879.1",0.516],["NP_001096457.1","NP_001072397.1",0.643],["NP_001096457.1","XP_002933024.2",0.58],["NP_001096457.1","XP_002938070.1",0.727],["NP_001096457.1","XP_002938755.1",0.615],["NP_001096457.1","XP_031753282.1",0.827],["NP_001096457.1","XP_031758513.1",0.614],["NP_001096457.1","XP_031758514.1",0.661],["XP_031758513.1","XP_002935038.3",0.587],["XP_031758513.1","XP_002936950.1",0.536],["XP_031758513.1","XP_002938070.1",0.634],["XP_031758513.1","XP_002938755.1",0.77],["XP_031758513.1","XP_031753282.1",0.609],["XP_031758513.1","XP_031758514.1",0.623],["XP_031758513.1","NP_001005073.1",0.523],["XP_031758513.1","NP_001005455.1",0.599],["XP_031758513.1","NP_001011085.1",0.68],["XP_031758513.1","NP_001032339.1",0.566],["XP_031758513.1","NP_001072397.1",0.586],["NP_001015955.1","NP_001004844.1",0.636],["NP_001015955.1","NP_001004942.1",0.631],["NP_001015955.1","NP_001005073.1",0.662],["NP_001015955.1","NP_001005455.1",0.603],["NP_001015955.1","NP_001011085.1",0.62],["NP_001015955.1","NP_001072397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