{"hash":"1288481700363522061","title":"Vesicle trafficking and immune signaling","description":"This cluster centers on intracellular transport and membrane organization (ER-Golgi transport, endosome-to-vacuole sorting, raft polarization, tight junction assembly) with accompanying immune-related processes (cytokine production, B cell differentiation, hemocyte proliferation). The common thread appears to be vesicle trafficking and membrane dynamics that influence immune signaling and cell communication. Some terms like myelination may reflect shared trafficking roles rather than direct immune function, but the overall theme remains vesicle transport in immune contexts.","confidence":"Medium","size":17,"edges":94,"triangles":244,"max_degree":16,"top_function":null,"members":[{"accession":"NP_001005138.1","go_terms":[]},{"accession":"NP_001007955.1","go_terms":["GO:0015031","GO:0045956","GO:0045806","GO:0050715"]},{"accession":"NP_001011464.1","go_terms":["GO:0006621","GO:0090004","GO:0006888","GO:0071340","GO:0006890"]},{"accession":"NP_001016287.1","go_terms":["GO:0032511"]},{"accession":"NP_001016638.1","go_terms":["GO:0045047","GO:0006465"]},{"accession":"NP_001016940.1","go_terms":["GO:0006487"]},{"accession":"NP_001072778.1","go_terms":[]},{"accession":"NP_001096521.1","go_terms":["GO:0032511"]},{"accession":"NP_001120902.1","go_terms":["GO:0002037","GO:0006888","GO:0008631","GO:0010917"]},{"accession":"NP_001107143.1","go_terms":["GO:0034116","GO:2000010","GO:0051044","GO:0070231","GO:2001238","GO:0008588","GO:0071848","GO:0051897","GO:0034112","GO:0045780","GO:0045994","GO:0010467","GO:1904058","GO:0051798","GO:0060662","GO:0045663","GO:0045662","GO:0045668","GO:0031295","GO:0048298","GO:0060559","GO:0002548","GO:0050830","GO:0060664","GO:0045416","GO:0061153","GO:0030168","GO:0051466","GO:0048388","GO:1901671","GO:1900074","GO:1904999","GO:1903140","GO:0032733","GO:0048566","GO:0071260","GO:0045190","GO:0051023","GO:0046325","GO:0002925","GO:0044130","GO:0002439","GO:2001206","GO:0090002","GO:0060789","GO:0030890","GO:0007257","GO:0045080","GO:0014009","GO:0046666","GO:0006959","GO:0045167","GO:0072577","GO:0050715","GO:0043491","GO:0030866","GO:0051533","GO:0032715","GO:0060693","GO:0048305","GO:0032800","GO:0038001","GO:0090200","GO:0033598","GO:0045429","GO:0045585","GO:0002740","GO:0043243","GO:0043242","GO:0050766","GO:0071803","GO:0007254","GO:0008625","GO:0007250","GO:0031663","GO:0045071","GO:0001782","GO:2001240","GO:1903514","GO:1903347","GO:0030316","GO:2000353","GO:0002636","GO:0060749","GO:0045453","GO:0051092","GO:0071812","GO:0008630","GO:0031296","GO:0097527","GO:0043374","GO:0070371","GO:2000343","GO:0000185","GO:0051384","GO:0033138","GO:0006919","GO:0002876","GO:0050901","GO:0010820","GO:0032729","GO:0061048","GO:0000060","GO:0071316","GO:0048535","GO:1904707","GO:0043588","GO:1901741","GO:2000334","GO:0071230","GO:0035509","GO:0030183","GO:0045084","GO:0042107","GO:0042100","GO:0042102","GO:0002158","GO:0030730","GO:0050995","GO:0032755","GO:0032753","GO:0010693","GO:0001937"]},{"accession":"XP_002939063.1","go_terms":["GO:1902043","GO:0034115","GO:0042552","GO:0050861","GO:0007605","GO:0045056","GO:0070830","GO:0090038","GO:0002337","GO:0035208","GO:0021762","GO:0001766","GO:0048172","GO:0048169","GO:0061028","GO:0070941"]},{"accession":"NP_001016297.1","go_terms":["GO:0006506","GO:0035269","GO:0019348"]},{"accession":"NP_001016333.1","go_terms":["GO:0032979","GO:0015031"]},{"accession":"NP_001016867.1","go_terms":["GO:1904103","GO:0006506"]},{"accession":"NP_001106448.1","go_terms":["GO:1902043","GO:0034115","GO:0042552","GO:0050861","GO:0007605","GO:0045056","GO:0070830","GO:0090038","GO:0002337","GO:0035208","GO:0021762","GO:0001766","GO:0048172","GO:0048169","GO:0061028","GO:0070941"]},{"accession":"NP_001037928.1","go_terms":["GO:0070072"]},{"accession":"XP_002937690.1","go_terms":["GO:0009607","GO:0050884","GO:0097091","GO:0044381","GO:0060349","GO:0046597","GO:0035456","GO:0035455","GO:0030282","GO:0099638"]}],"graph":[["NP_001007955.1","NP_001096521.1",0.522],["NP_001007955.1","NP_001072778.1",0.514],["NP_001007955.1","NP_001037928.1",0.601],["NP_001007955.1","NP_001016940.1",0.6],["NP_001007955.1","NP_001016297.1",0.566],["NP_001007955.1","NP_001011464.1",0.566],["NP_001106448.1","NP_001005138.1",0.576],["NP_001106448.1","NP_001016287.1",0.572],["NP_001106448.1","NP_001016638.1",0.606],["NP_001106448.1","NP_001016867.1",0.556],["NP_001106448.1","NP_001016940.1",0.587],["NP_001106448.1","NP_001037928.1",0.637],["NP_001106448.1","NP_001072778.1",0.581],["NP_001106448.1","NP_001107143.1",0.624],["NP_001106448.1","XP_002939063.1",0.594],["NP_001016333.1","NP_001016287.1",0.526],["NP_001016333.1","NP_001016638.1",0.551],["NP_001016333.1","NP_001016867.1",0.506],["NP_001016333.1","NP_001016940.1",0.676],["NP_001016333.1","NP_001037928.1",0.522],["NP_001016333.1","NP_001072778.1",0.55],["NP_001016333.1","NP_001096521.1",0.51],["NP_001016333.1","NP_001120902.1",0.506],["NP_001037928.1","NP_001005138.1",0.622],["NP_001037928.1","NP_001016287.1",0.55],["NP_001037928.1","NP_001016638.1",0.68],["NP_001037928.1","NP_001016867.1",0.535],["NP_001037928.1","NP_001016940.1",0.636],["NP_001037928.1","NP_001072778.1",0.572],["NP_001037928.1","XP_002937690.1",0.59],["NP_001037928.1","NP_001120902.1",0.574],["NP_001037928.1","NP_001107143.1",0.645],["NP_001037928.1","XP_002939063.1",0.566],["NP_001072778.1","NP_001005138.1",0.708],["NP_001072778.1","NP_001011464.1",0.541],["NP_001072778.1","NP_001016638.1",0.574],["NP_001072778.1","NP_001016940.1",0.654],["NP_001072778.1","NP_001096521.1",0.602],["NP_001072778.1","NP_001107143.1",0.507],["NP_0010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