{"hash":"1160914823957338074","title":"LPS-Triggered Inflammation and Lipid Metabolism","description":"The top GO terms include response to lipopolysaccharide, prostaglandin metabolic process, fatty acid omega-oxidation, and nitrosative stress response, plus extracellular regulation of signal transduction. This pattern points to a cluster of proteins tied to innate immune response to bacterial components and lipid mediator signaling, with supporting detoxification and redox regulation activities. The shared theme centers on LPS-induced inflammation and lipid metabolism pathways.","confidence":"High","size":15,"edges":76,"triangles":256,"max_degree":12,"top_function":"respiratory system process","members":[{"accession":"XP_031751074.1","go_terms":[]},{"accession":"NP_001011423.1","go_terms":["GO:0019595","GO:0051160","GO:0003016","GO:0042572","GO:0032496","GO:0042573","GO:0009809","GO:0033859","GO:0000947","GO:0006116","GO:0046688","GO:1900116","GO:0033498","GO:0018119","GO:0046370","GO:0051409","GO:0019518","GO:0045777","GO:0043458","GO:0046294","GO:1901159","GO:0006062","GO:0010430","GO:0006068","GO:0006069","GO:0006633","GO:0006693","GO:0097327"]},{"accession":"XP_002934814.1","go_terms":["GO:0019595","GO:0051160","GO:0003016","GO:0042572","GO:0032496","GO:0042573","GO:0009809","GO:0033859","GO:0000947","GO:0006116","GO:0046688","GO:1900116","GO:0033498","GO:0018119","GO:0046370","GO:0051409","GO:0019518","GO:0045777","GO:0043458","GO:0046294","GO:1901159","GO:0006062","GO:0010430","GO:0006068","GO:0006069","GO:0006633","GO:0006693","GO:0097327"]},{"accession":"XP_002934816.1","go_terms":["GO:0019595","GO:0051160","GO:0003016","GO:0042572","GO:0032496","GO:0042573","GO:0009809","GO:0033859","GO:0000947","GO:0006116","GO:0046688","GO:1900116","GO:0033498","GO:0018119","GO:0046370","GO:0051409","GO:0019518","GO:0045777","GO:0043458","GO:0046294","GO:1901159","GO:0006062","GO:0010430","GO:0006068","GO:0006069","GO:0006633","GO:0006693","GO:0097327"]},{"accession":"NP_001011431.1","go_terms":["GO:0019595","GO:0051160","GO:0003016","GO:0042572","GO:0032496","GO:0042573","GO:0009809","GO:0033859","GO:0000947","GO:0006116","GO:0046688","GO:1900116","GO:0033498","GO:0018119","GO:0046370","GO:0051409","GO:0019518","GO:0045777","GO:0043458","GO:0046294","GO:1901159","GO:0006062","GO:0010430","GO:0006068","GO:0006069","GO:0006633","GO:0006693","GO:0097327"]},{"accession":"NP_001027487.1","go_terms":["GO:0019732","GO:0019731","GO:0060349","GO:0006881","GO:0001503","GO:0006879","GO:0048260","GO:1900025","GO:0045071","GO:0044793","GO:0002227","GO:0045669","GO:1900229","GO:0043123","GO:0090091","GO:2001205","GO:1902732","GO:0051092","GO:0032780","GO:0098707","GO:0034145","GO:0001895","GO:0071281","GO:0033690","GO:0031665","GO:0032680","GO:0010756","GO:0033572","GO:2000308","GO:1900159"]},{"accession":"XP_002934810.3","go_terms":["GO:0019595","GO:0051160","GO:0003016","GO:0042572","GO:0032496","GO:0042573","GO:0009809","GO:0033859","GO:0000947","GO:0006116","GO:0046688","GO:1900116","GO:0033498","GO:0018119","GO:0046370","GO:0051409","GO:0019518","GO:0045777","GO:0043458","GO:0046294","GO:1901159","GO:0006062","GO:0010430","GO:0006068","GO:0006069","GO:0006633","GO:0006693","GO:0097327"]},{"accession":"NP_001011264.1","go_terms":["GO:0019595","GO:0051160","GO:0003016","GO:0042572","GO:0032496","GO:0042573","GO:0009809","GO:0033859","GO:0000947","GO:0006116","GO:0046688","GO:1900116","GO:0033498","GO:0018119","GO:0046370","GO:0051409","GO:0019518","GO:0045777","GO:0043458","GO:0046294","GO:1901159","GO:0006062","GO:0010430","GO:0006068","GO:0006069","GO:0006633","GO:0006693","GO:0097327","GO:0019640","GO:0006970","GO:0055114","GO:0009725","GO:0042493","GO:0031667","GO:0046686","GO:1902600","GO:0042853","GO:0019404","GO:0006189","GO:0006740"]},{"accession":"XP_002934817.2","go_terms":["GO:0019595","GO:0051160","GO:0003016","GO:0042572","GO:0032496","GO:0042573","GO:0009809","GO:0033859","GO:0000947","GO:0006116","GO:0046688","GO:1900116","GO:0033498","GO:0018119","GO:0046370","GO:0051409","GO:0019518","GO:0045777","GO:0043458","GO:0046294","GO:1901159","GO:0006062","GO:0010430","GO:0006068","GO:0006069","GO:0006633","GO:0006693","GO:0097327"]},{"accession":"XP_002934819.2","go_terms":["GO:0019595","GO:0051160","GO:0003016","GO:0042572","GO:0032496","GO:0042573","GO:0009809","GO:0033859","GO:0000947","GO:0006116","GO:0046688","GO:1900116","GO:0033498","GO:0018119","GO:0046370","GO:0051409","GO:0019518","GO:0045777","GO:0043458","GO:0046294","GO:1901159","GO:0006062","GO:0010430","GO:0006068","GO:0006069","GO:0006633","GO:0006693","GO:0097327"]},{"accession":"XP_017946422.2","go_terms":["GO:0019595","GO:0051160","GO:0003016","GO:0042572","GO:0032496","GO:0042573","GO:0009809","GO:0033859","GO:0000947","GO:0006116","GO:0046688","GO:1900116","GO:0033498","GO:0018119","GO:0046370","GO:0051409","GO:0019518","GO:0045777","GO:0043458","GO:0046294","GO:1901159","GO:0006062","GO:0010430","GO:0006068","GO:0006069","GO:0006633","GO:0006693","GO:0097327"]},{"accession":"NP_001011502.1","go_terms":["GO:0019595","GO:0051160","GO:0003016","GO:0042572","GO:0032496","GO:0042573","GO:0009809","GO:0033859","GO:0000947","GO:0006116","GO:0046688","GO:1900116","GO:0033498","GO:0018119","GO:0046370","GO:0051409","GO:0019518","GO:0045777","GO:0043458","GO:0046294","GO:1901159","GO:0006062","GO:0010430","GO:0006068","GO:0006069","GO:0006633","GO:0006693","GO:0097327"]},{"accession":"XP_004911087.1","go_terms":["GO:1902600","GO:0055114"]},{"accession":"NP_001011391.1","go_terms":["GO:0019595","GO:0051160","GO:0003016","GO:0042572","GO:0032496","GO:0042573","GO:0009809","GO:0033859","GO:0000947","GO:0006116","GO:0046688","GO:1900116","GO:0033498","GO:0018119","GO:0046370","GO:0051409","GO:0019518","GO:0045777","GO:0043458","GO:0046294","GO:1901159","GO:0006062","GO:0010430","GO:0006068","GO:0006069","GO:0006633","GO:0006693","GO:0097327"]},{"accession":"NP_001025581.1","go_terms":["GO:0019595","GO:0051160","GO:0003016","GO:0042572","GO:0032496","GO:0042573","GO:0009809","GO:0033859","GO:0000947","GO:0006116","GO:0046688","GO:1900116","GO:0033498","GO:0018119","GO:0046370","GO:0051409","GO:0019518","GO:0045777","GO:0043458","GO:0046294","GO:1901159","GO:0006062","GO:0010430","GO:0006068","GO:0006069","GO:0006633","GO:0006693","GO:0097327"]}],"graph":[["XP_002934810.3","XP_004911087.1",0.765],["XP_002934810.3","XP_017946422.2",0.725],["XP_002934810.3","NP_001011264.1",0.734],["XP_002934810.3","NP_001011391.1",0.72],["XP_002934810.3","NP_001011423.1",0.699],["XP_002934810.3","NP_001011431.1",0.724],["XP_002934810.3","NP_001011502.1",0.774],["XP_002934810.3","NP_001025581.1",0.742],["XP_002934810.3","XP_002934814.1",0.755],["XP_002934810.3","XP_002934816.1",0.757],["XP_002934810.3","XP_002934817.2",0.676],["XP_002934810.3","XP_002934819.2",0.767],["NP_001011264.1","NP_001011391.1",0.616],["NP_001011264.1","NP_001011423.1",0.606],["NP_001011264.1","NP_001011431.1",0.617],["NP_001011264.1","NP_001011502.1",0.706],["NP_001011264.1","NP_001025581.1",0.593],["NP_001011264.1","XP_002934814.1",0.631],["NP_001011264.1","XP_002934816.1",0.76],["NP_001011264.1","XP_002934817.2",0.799],["NP_001011264.1","XP_002934819.2",0.672],["NP_001011264.1","XP_017946422.2",0.655],["NP_001011423.1","NP_001011391.1",0.83],["NP_001011423.1","NP_001011431.1",0.882],["NP_001011423.1","NP_001011502.1",0.76],["NP_001011423.1","NP_001025581.1",0.818],["NP_001011423.1","XP_002934814.1",0.823],["NP_001011423.1","XP_002934816.1",0.786],["NP_001011423.1","XP_002934817.2",0.767],["NP_001011423.1","XP_002934819.2",0.77],["NP_001011423.1","XP_004911087.1",0.624],["NP_001011423.1","XP_017946422.2",0.726],["XP_002934817.2","XP_004911087.1",0.508],["XP_002934817.2","XP_017946422.2",0.757],["XP_002934817.2","NP_001011391.1",0.793],["XP_002934817.2","NP_001011431.1",0.797],["XP_002934817.2","NP_001011502.1",0.819],["XP_002934817.2","NP_001025581.1",0.798],["XP_002934817.2","XP_002934814.1",0.804],["XP_002934817.2","XP_002934816.1",0.766],["XP_002934817.2","XP_002934819.2",0.81],["XP_031751074.1","XP_004911087.1",0.541],["XP_017946422.2","XP_002934814.1",0.781],["XP_017946422.2","XP_002934816.1",0.76],["XP_017946422.2","XP_002934819.2",0.736],["XP_017946422.2","NP_001011391.1",0.741],["XP_017946422.2","NP_001011431.1",0.765],["XP_017946422.2","NP_001011502.1",0.734],["XP_017946422.2","NP_001025581.1",0.744],["XP_002934816.1","XP_004911087.1",0.621],["XP_002934816.1","NP_001011391.1",0.755],["XP_002934816.1","NP_001011431.1",0.819],["XP_002934816.1","NP_001011502.1",0.802],["XP_002934816.1","NP_001025581.1",0.785],["XP_002934816.1","XP_002934814.1",0.762],["XP_002934816.1","XP_002934819.2",0.766],["NP_001011502.1","NP_001011391.1",0.776],["NP_001011502.1","NP_001011431.1",0.791],["NP_001011502.1","NP_001025581.1",0.812],["NP_001011502.1","XP_002934814.1",0.79],["NP_001011502.1","XP_002934819.2",0.772],["NP_001011502.1","XP_004911087.1",0.581],["NP_001025581.1","NP_001011391.1",0.78],["NP_001025581.1","NP_001011431.1",0.801],["NP_001025581.1","XP_002934814.1",0.751],["NP_001025581.1","XP_002934819.2",0.769],["NP_001025581.1","XP_004911087.1",0.603],["NP_001011431.1","NP_001011391.1",0.82],["NP_001011431.1","XP_002934814.1",0.82],["NP_001011431.1","XP_002934819.2",0.844],["NP_001011391.1","XP_002934814.1",0.793],["NP_001011391.1","XP_002934819.2",0.754],["NP_001011391.1","XP_004911087.1",0.616],["XP_002934819.2","XP_004911087.1",0.567],["XP_002934819.2","XP_002934814.1",0.822],["XP_004911087.1","XP_002934814.1",0.684]],"all_go_terms":{"GO:0032496":12,"GO:0006069":12,"GO:0019518":12,"GO:0010430":12,"GO:0045777":12,"GO:0046294":12,"GO:0006693":12,"GO:1901159":12,"GO:1900116":12,"GO:0051409":12,"GO:0009809":12,"GO:0006068":12,"GO:0033498":12,"GO:0000947":12,"GO:0043458":12,"GO:0046688":12,"GO:0046370":12,"GO:0018119":12,"GO:0006116":12,"GO:0033859":12,"GO:0003016":12,"GO:0042573":12,"GO:0006062":12,"GO:0051160":12,"GO:0097327":12,"GO:0019595":12,"GO:0006633":12,"GO:0042572":12,"GO:0006881":1,"GO:0031665":1,"GO:0051092":1,"GO:0033572":1,"GO:0032780":1,"GO:0043123":1,"GO:0019731":1,"GO:0048260":1,"GO:1900159":1,"GO:0090091":1,"GO:0060349":1,"GO:0034145":1,"GO:0098707":1,"GO:0071281":1,"GO:0044793":1,"GO:0001895":1,"GO:1900229":1,"GO:0001503":1,"GO:2000308":1,"GO:0010756":1,"GO:0045071":1,"GO:1900025":1,"GO:0019732":1,"GO:0045669":1,"GO:0006879":1,"GO:0033690":1,"GO:0032680":1,"GO:1902732":1,"GO:2001205":1,"GO:0002227":1,"GO:0006189":1,"GO:0055114":2,"GO:0042493":1,"GO:0031667":1,"GO:0009725":1,"GO:0042853":1,"GO:0046686":1,"GO:1902600":2,"GO:0019404":1,"GO:0006970":1,"GO:0019640":1,"GO:0006740":1},"recipe_readded":[]}