{"hash":"1043256683688778580","title":"Schwann cell function and nerve regeneration","description":"The cluster centers on nervous system development and repair, with terms like somatic motor neuron differentiation, neurofilament cytoskeleton organization, and (negative regulation of) Schwann cell migration/proliferation involved in axon regeneration. Additional terms such as epidermal growth factor receptor signaling and receptor recycling point to cellular signaling and membrane trafficking relevant to Schwann cells and neurons, while lipid biosynthesis terms (ergosterol, ceramide) likely reflect membrane biology in neural cells and ECM-associated processes (collagen biosynthesis). Together these suggest a cohesive theme of peripheral nerve development and repair mediated by Schwann cells and associated neurons.","confidence":"High","size":18,"edges":150,"triangles":769,"max_degree":17,"top_function":null,"members":[{"accession":"NP_001001210.1","go_terms":["GO:0001306","GO:0050881","GO:0021523","GO:0050884","GO:0060052","GO:1905045","GO:0051935","GO:0046513","GO:0032964","GO:0044257","GO:0002238","GO:1900148"]},{"accession":"NP_001011272.1","go_terms":["GO:0032581","GO:0009737","GO:0048309","GO:0050916","GO:0071786","GO:0051292","GO:0050913","GO:0007084","GO:0032596","GO:0034976"]},{"accession":"NP_001016135.1","go_terms":["GO:0033211","GO:1990522","GO:0019835","GO:0006882","GO:0061042","GO:1901223"]},{"accession":"NP_001016539.1","go_terms":["GO:0006696"]},{"accession":"NP_001016600.2","go_terms":["GO:0007173","GO:0001881"]},{"accession":"NP_001017083.1","go_terms":["GO:0038018","GO:0016558","GO:0030433","GO:0060816","GO:0051865","GO:0042787","GO:0046621","GO:1900095","GO:0070936","GO:0045087","GO:0009896","GO:0046007","GO:1902187","GO:0035372","GO:0000185","GO:0061470","GO:0046597","GO:1901224","GO:0033280","GO:0007026","GO:0042098","GO:0043029","GO:1903886","GO:1903883","GO:0048536","GO:0045623","GO:0048535","GO:0070534","GO:0043123","GO:0050999","GO:1903265","GO:0060546","GO:0006914","GO:0001782","GO:0002635","GO:0048490","GO:0032897","GO:0007014","GO:0051092","GO:0097039","GO:0051607","GO:0061158","GO:0031664","GO:0031030","GO:0032186","GO:1902364","GO:0000921","GO:0031578","GO:0097271","GO:0044810","GO:0090337","GO:0016567","GO:0039536","GO:0002250","GO:0060544","GO:0000122","GO:0034121","GO:0043066","GO:0000209","GO:0071157","GO:0033151","GO:0033209","GO:0009048","GO:0036205","GO:0046328","GO:2000620","GO:0042981","GO:0007250","GO:0070512","GO:0085020","GO:0070535","GO:1903762","GO:1903721","GO:1901253","GO:0090073","GO:0010936","GO:0097051","GO:0036010","GO:0030970"]},{"accession":"NP_001029117.1","go_terms":["GO:0042552","GO:0043652","GO:0031133","GO:0048741","GO:0070782","GO:0010961"]},{"accession":"NP_001090654.1","go_terms":["GO:0035356","GO:0034389","GO:0061668","GO:0010890","GO:0030730","GO:0010866"]},{"accession":"NP_001116958.1","go_terms":["GO:0097639","GO:0097638","GO:0010923","GO:0097640","GO:0042116","GO:0043030","GO:0006809","GO:0002537"]},{"accession":"NP_001120539.1","go_terms":["GO:0050832","GO:0006629","GO:0044154","GO:0070868","GO:0043971","GO:0043970","GO:0006696","GO:0006695","GO:0016132"]},{"accession":"NP_001231837.1","go_terms":["GO:0007173","GO:0001881"]},{"accession":"NP_989282.1","go_terms":["GO:0006888"]},{"accession":"XP_002931506.2","go_terms":["GO:0060628","GO:0060576"]},{"accession":"XP_002933780.2","go_terms":["GO:0019915"]},{"accession":"XP_002935059.2","go_terms":[]},{"accession":"XP_004919448.1","go_terms":["GO:1905515","GO:0042733","GO:0021532","GO:1904491"]},{"accession":"XP_012813731.3","go_terms":["GO:0031505","GO:1902230","GO:0007601","GO:0006506","GO:0010506","GO:0045494","GO:0042771"]},{"accession":"XP_017946441.2","go_terms":[]}],"graph":[["NP_001116958.1","NP_001001210.1",0.559],["NP_001116958.1","NP_001011272.1",0.623],["NP_001116958.1","NP_001016135.1",0.644],["NP_001116958.1","NP_001016539.1",0.588],["NP_001116958.1","NP_001016600.2",0.59],["NP_001116958.1","NP_001017083.1",0.643],["NP_001116958.1","NP_001029117.1",0.678],["NP_001116958.1","NP_001090654.1",0.583],["NP_001116958.1","NP_001120539.1",0.659],["NP_001116958.1","NP_001231837.1",0.542],["NP_001116958.1","NP_989282.1",0.627],["NP_001116958.1","XP_002931506.2",0.657],["NP_001116958.1","XP_002933780.2",0.648],["NP_001116958.1","XP_002935059.2",0.606],["NP_001116958.1","XP_004919448.1",0.614],["NP_001116958.1","XP_012813731.3",0.623],["NP_001116958.1","XP_017946441.2",0.624],["XP_004919448.1","XP_002933780.2",0.562],["XP_004919448.1","XP_002935059.2",0.642],["XP_004919448.1","XP_017946441.2",0.54],["XP_004919448.1","NP_001001210.1",0.596],["XP_004919448.1","NP_001016135.1",0.65],["XP_004919448.1","NP_001016539.1",0.587],["XP_004919448.1","NP_001016600.2",0.578],["XP_004919448.1","NP_001017083.1",0.565],["XP_004919448.1","NP_001029117.1",0.572],["XP_004919448.1","NP_001090654.1",0.615],["XP_004919448.1","NP_001120539.1",0.623],["XP_004919448.1","NP_001231837.1",0.559],["XP_004919448.1","NP_989282.1",0.577],["XP_004919448.1","XP_002931506.2",0.645],["XP_002935059.2","XP_012813731.3",0.51],["XP_002935059.2","XP_017946441.2",0.593],["XP_002935059.2","NP_001001210.1",0.576],["XP_002935059.2","NP_001011272.1",0.604],["XP_002935059.2","NP_001016135.1",0.606],["XP_002935059.2","NP_001016539.1",0.624],["XP_002935059.2","NP_001016600.2",0.613],["XP_002935059.2","NP_001017083.1",0.645],["XP_002935059.2","NP_001029117.1",0.613],["XP_002935059.2","NP_001090654.1",0.597],["XP_002935059.2","NP_001120539.1",0.613],["XP_002935059.2","NP_001231837.1",0.567],["XP_002935059.2","NP_989282.1",0.566],["XP_002935059.2","XP_002931506.2",0.606],["XP_002935059.2","XP_002933780.2",0.67],["NP_001029117.1","NP_001001210.1",0.631],["NP_001029117.1","NP_001011272.1",0.577],["NP_001029117.1","NP_001016135.1",0.659],["NP_0010291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