{"hash":"1003851387584057163","title":"Neuropeptide signaling and inflammatory responses","description":"The cluster is enriched for neuropeptide signaling (GO:0007218) and several immune/inflammatory related responses (to lipopolysaccharide, leukotriene production) as well as feeding-related signaling (response to food) and retinoic acid signaling, suggesting a link between neural signaling and inflammatory/immune processes. The ER protein folding and autophagosome assembly terms imply concurrent cellular stress response roles that can accompany neuroimmune signaling. Overall, a cohesive theme of neuropeptide signaling intertwined with inflammatory and metabolic responses.","confidence":"Medium","size":12,"edges":10,"triangles":3,"max_degree":6,"top_function":null,"members":[{"accession":"NP_001016462.1","go_terms":["GO:0034975","GO:0000045"]},{"accession":"NP_001135705.1","go_terms":[]},{"accession":"XP_004911179.1","go_terms":["GO:0033327","GO:0032496","GO:0043085","GO:0098869","GO:0014070","GO:0019372","GO:0019370","GO:0008285","GO:0032526","GO:0070207","GO:0034097","GO:2001300","GO:0070268","GO:0071277","GO:0001516","GO:0002526","GO:0002540","GO:0002544","GO:0071449"]},{"accession":"NP_988982.1","go_terms":["GO:0070973","GO:0006888","GO:0006886","GO:1903071","GO:0035584","GO:0001649","GO:1904154","GO:2001244","GO:0051561","GO:0032471","GO:0080022","GO:0080127","GO:0048826","GO:0009641"]},{"accession":"NP_001016103.1","go_terms":[]},{"accession":"NP_001254820.1","go_terms":["GO:0007217"]},{"accession":"XP_002933831.1","go_terms":["GO:0009236","GO:0017000","GO:0035690","GO:0006656","GO:0019919","GO:0009102","GO:0030488","GO:0016049","GO:0018012","GO:0006744","GO:0010189","GO:0016126","GO:0043985","GO:0070476","GO:0046690","GO:0002098","GO:0000056","GO:0001300","GO:0090398","GO:0030961","GO:0006370","GO:0009877","GO:0002181","GO:0007051","GO:0016571","GO:0035572","GO:0007059","GO:0071891","GO:0035573","GO:0018013","GO:0036265","GO:0006596","GO:0000154"]},{"accession":"XP_004911995.1","go_terms":["GO:0010459","GO:0007218","GO:0003254","GO:0002438","GO:0045777","GO:0032099","GO:0060079","GO:0021510","GO:0051930","GO:0046676","GO:0043278","GO:0060135","GO:0070253","GO:0030103"]},{"accession":"XP_031752738.1","go_terms":[]},{"accession":"XP_031760348.1","go_terms":["GO:0032094"]},{"accession":"XP_002943003.1","go_terms":["GO:0032094"]},{"accession":"NP_001015744.2","go_terms":["GO:0007626","GO:0007218","GO:0002118","GO:0014009","GO:0051867","GO:0001964","GO:0071871","GO:0007268","GO:0019233","GO:0071305","GO:2000987","GO:0071696","GO:0001662"]}],"graph":[["NP_001254820.1","XP_031760348.1",0.511],["NP_001254820.1","XP_004911995.1",0.53],["XP_031760348.1","XP_004911995.1",0.582],["XP_004911179.1","XP_004911995.1",0.558],["XP_004911179.1","NP_001016462.1",0.652],["NP_001016462.1","NP_001135705.1",0.565],["NP_001016462.1","NP_988982.1",0.619],["NP_001016462.1","XP_004911995.1",0.56],["NP_988982.1","XP_004911995.1",0.543],["XP_004911995.1","XP_031752738.1",0.506]],"all_go_terms":{"GO:0000045":1,"GO:0034975":1,"GO:0043085":1,"GO:0032496":1,"GO:0032526":1,"GO:0014070":1,"GO:0002540":1,"GO:2001300":1,"GO:0098869":1,"GO:0071277":1,"GO:0070207":1,"GO:0071449":1,"GO:0034097":1,"GO:0033327":1,"GO:0002526":1,"GO:0002544":1,"GO:0001516":1,"GO:0008285":1,"GO:0070268":1,"GO:0019370":1,"GO:0019372":1,"GO:1903071":1,"GO:0001649":1,"GO:0032471":1,"GO:0080022":1,"GO:0080127":1,"GO:2001244":1,"GO:0006886":1,"GO:0006888":1,"GO:0009641":1,"GO:1904154":1,"GO:0048826":1,"GO:0051561":1,"GO:0035584":1,"GO:0070973":1,"GO:0007217":1,"GO:0007051":1,"GO:0006370":1,"GO:0016126":1,"GO:0030488":1,"GO:0000056":1,"GO:0002181":1,"GO:0035573":1,"GO:0043985":1,"GO:0071891":1,"GO:0006596":1,"GO:0019919":1,"GO:0036265":1,"GO:0000154":1,"GO:0009877":1,"GO:0090398":1,"GO:0016571":1,"GO:0007059":1,"GO:0006656":1,"GO:0017000":1,"GO:0030961":1,"GO:0035690":1,"GO:0006744":1,"GO:0018012":1,"GO:0009236":1,"GO:0010189":1,"GO:0002098":1,"GO:0018013":1,"GO:0016049":1,"GO:0070476":1,"GO:0035572":1,"GO:0001300":1,"GO:0009102":1,"GO:0046690":1,"GO:0060135":1,"GO:0051930":1,"GO:0003254":1,"GO:0032099":1,"GO:0060079":1,"GO:0030103":1,"GO:0002438":1,"GO:0007218":2,"GO:0070253":1,"GO:0045777":1,"GO:0010459":1,"GO:0043278":1,"GO:0021510":1,"GO:0046676":1,"GO:0032094":2,"GO:0071871":1,"GO:0051867":1,"GO:0007626":1,"GO:2000987":1,"GO:0071696":1,"GO:0001964":1,"GO:0007268":1,"GO:0019233":1,"GO:0014009":1,"GO:0071305":1,"GO:0001662":1,"GO:0002118":1},"recipe_readded":["XP_031762211.1","NP_001107395.1","NP_001011290.1","NP_001005067.1","XP_012820060.1","NP_001107400.1","NP_001116287.1","XP_031750565.1","XP_002941252.1","NP_001027487.1","XP_017953344.1","NP_001016208.1","XP_031762756.1","NP_001297042.1","XP_002937501.1","XP_031759879.1","XP_012817558.2","XP_031751074.1","XP_002934115.1","XP_031753228.1"]}