{"hash":"2079028167449652120","title":"Notch-regulated development and patterning","description":"The top terms center on Notch signaling regulation (positive and negative) and development across multiple tissues (follicle, intestinal epithelium, hypochord, compartments, meiosis), plus pattern specification, suggesting the cluster represents proteins involved in signaling-driven development and tissue patterning rather than a single tissue-specific function.","confidence":"Medium","size":22,"edges":75,"triangles":153,"max_degree":14,"top_function":null,"members":[{"accession":"XP_035683836.1","go_terms":[]},{"accession":"XP_035665277.1","go_terms":["GO:0009247","GO:0009405","GO:0097502","GO:0008654","GO:0007631","GO:0009413","GO:0010125","GO:0009414","GO:0072708","GO:0071793","GO:0009744","GO:0006490","GO:0005978","GO:0005985","GO:0010555","GO:0033577","GO:0006506","GO:0006006","GO:0019252"]},{"accession":"XP_035668072.1","go_terms":[]},{"accession":"XP_035665895.1","go_terms":[]},{"accession":"XP_035683407.1","go_terms":["GO:0075015","GO:0005989","GO:0060054","GO:0060058","GO:0007341","GO:0006486","GO:0048147","GO:0018146","GO:0060055","GO:0030879","GO:0060046","GO:0007339","GO:0006688","GO:0045136","GO:0021680","GO:0008542","GO:0002526","GO:0006029"]},{"accession":"XP_035657367.1","go_terms":["GO:0075015","GO:0042248","GO:0010493","GO:0018258","GO:0080147","GO:0010405","GO:0030311","GO:0001744","GO:0007299","GO:0048354"]},{"accession":"XP_035691228.1","go_terms":["GO:0055016","GO:0032092","GO:0001541","GO:0036011","GO:0045747","GO:0007386","GO:0060576","GO:0016267","GO:0002315","GO:1902367","GO:0007143"]},{"accession":"XP_035658585.1","go_terms":["GO:0075015","GO:0042248","GO:0010493","GO:0018258","GO:0080147","GO:0010405","GO:0030311","GO:0001744","GO:0007299","GO:0048354","GO:0055016","GO:0032092","GO:0001541","GO:0036011","GO:0045747","GO:0007386","GO:0060576","GO:0016267","GO:0002315","GO:1902367","GO:0007143"]},{"accession":"XP_035666477.1","go_terms":["GO:0030206","GO:0051216","GO:0046398","GO:0001958","GO:0050652","GO:0050653","GO:0050650","GO:0050651","GO:0051923","GO:0060349","GO:0019276","GO:0045880","GO:0009954","GO:0002063","GO:0030279","GO:0060876","GO:0075015","GO:0005989","GO:0060054","GO:0060058","GO:0007341","GO:0006486","GO:0048147","GO:0018146","GO:0060055","GO:0030879","GO:0060046","GO:0007339","GO:0006688","GO:0045136","GO:0021680","GO:0055016","GO:0032092","GO:0001541","GO:0036011","GO:0045747","GO:0007386","GO:0060576","GO:0016267","GO:0002315","GO:1902367","GO:0007143"]},{"accession":"XP_035671555.1","go_terms":["GO:0075015","GO:0042248","GO:0010493","GO:0018258","GO:0080147","GO:0010405","GO:0030311","GO:0001744","GO:0007299","GO:0048354"]},{"accession":"XP_035672024.1","go_terms":["GO:0046718","GO:0006310","GO:0006278","GO:0075713","GO:0075732","GO:0015074","GO:0006260","GO:0039651","GO:1903704","GO:2000327","GO:0014912","GO:0003335","GO:2001153","GO:0045454","GO:0071375","GO:0043488","GO:0044179","GO:0006308","GO:0046856","GO:1900087","GO:0090502","GO:0006284","GO:0070301","GO:2000466","GO:0006915","GO:1903507","GO:0080111","GO:0007568","GO:0071320","GO:0042493","GO:0006313"]},{"accession":"XP_035682631.1","go_terms":["GO:0005975","GO:0006487"]},{"accession":"XP_035669493.1","go_terms":["GO:0075015","GO:0042248","GO:0010493","GO:0018258","GO:0080147","GO:0010405","GO:0030311","GO:0001744","GO:0007299","GO:0048354"]},{"accession":"XP_035680054.1","go_terms":["GO:2000327","GO:0014912","GO:0003335","GO:2001153","GO:0045454","GO:0071375","GO:0043488","GO:0044179","GO:0006308","GO:0046856","GO:1900087","GO:0090502","GO:0006284","GO:0070301","GO:2000466","GO:0006915","GO:1903507","GO:0006310","GO:0080111","GO:0007568","GO:0071320","GO:0042493","GO:0006313"]},{"accession":"XP_035691293.1","go_terms":["GO:0030206","GO:0051216","GO:0046398","GO:0001958","GO:0050652","GO:0050653","GO:0050650","GO:0050651","GO:0051923","GO:0060349","GO:0019276","GO:0045880","GO:0009954","GO:0002063","GO:0030279","GO:0060876","GO:0075015","GO:0005989","GO:0060054","GO:0060058","GO:0007341","GO:0006486","GO:0048147","GO:0018146","GO:0060055","GO:0030879","GO:0060046","GO:0007339","GO:0006688","GO:0045136","GO:0021680","GO:0055016","GO:0032092","GO:0001541","GO:0036011","GO:0045747","GO:0007386","GO:0060576","GO:0016267","GO:0002315","GO:1902367","GO:0007143"]},{"accession":"XP_035658167.1","go_terms":["GO:2000324","GO:1905213","GO:2001034","GO:0031987","GO:0050728","GO:0006986","GO:0006260","GO:1905205","GO:0000082","GO:0060316","GO:0035562","GO:0022011","GO:2000002","GO:0030846","GO:1903799","GO:0010780","GO:0006196","GO:0046086","GO:0051343","GO:0000903","GO:0031573","GO:0001569","GO:0043029","GO:0016576","GO:0006685","GO:0097552","GO:0030847","GO:0098609","GO:0051037","GO:0060079","GO:0010719","GO:0051531","GO:0051533","GO:0030437","GO:0033173","GO:0014898","GO:0010791","GO:0007498","GO:0021762","GO:0051321","GO:0014883","GO:0005981","GO:0072462","GO:0001946","GO:2001241","GO:1903244","GO:0010288","GO:0070262","GO:0043278","GO:0051315","GO:0007114","GO:0050774","GO:0070940","GO:0061587","GO:0005513","GO:1900486","GO:1901901","GO:0035753","GO:0030324","GO:0034501","GO:0032516","GO:0035690","GO:1902660","GO:1990918","GO:1900490","GO:1903501","GO:0099566","GO:0030182","GO:0048741","GO:0014044","GO:0009245","GO:0042220","GO:0006888","GO:0060487","GO:0036496","GO:0009742","GO:0005977","GO:0005979","GO:0001837","GO:0001915","GO:0016311","GO:0007159"]},{"accession":"XP_035695995.1","go_terms":["GO:0075015","GO:0042248","GO:0010493","GO:0018258","GO:0080147","GO:0010405","GO:0030311","GO:0001744","GO:0007299","GO:0048354","GO:0055016","GO:0032092","GO:0001541","GO:0036011","GO:0045747","GO:0007386","GO:0060576","GO:0016267","GO:0002315","GO:1902367","GO:0007143"]},{"accession":"XP_035679909.1","go_terms":["GO:0055016","GO:0032092","GO:0001541","GO:0036011","GO:0045747","GO:0007386","GO:0060576","GO:0016267","GO:0002315","GO:1902367","GO:0007143"]},{"accession":"XP_035679088.1","go_terms":[]},{"accession":"XP_035663245.1","go_terms":["GO:0046835","GO:0006000","GO:0006006","GO:0006096"]},{"accession":"XP_035686028.1","go_terms":["GO:0048575","GO:0030154","GO:0060409","GO:0042755","GO:0010229","GO:0010951","GO:0048240","GO:0007275","GO:0009911","GO:0009910","GO:0048510","GO:0009908"]},{"accession":"XP_035686348.1","go_terms":["GO:0048575","GO:0030154","GO:0060409","GO:0042755","GO:0010229","GO:0010951","GO:0048240","GO:0007275","GO:0009911","GO:0009910","GO:0048510","GO:0009908"]}],"graph":[["XP_035665277.1","XP_035657367.1",0.559],["XP_035665277.1","XP_035658585.1",0.658],["XP_035665277.1","XP_035665895.1",0.525],["XP_035665277.1","XP_035666477.1",0.62],["XP_035665277.1","XP_035669493.1",0.622],["XP_035665277.1","XP_035671555.1",0.571],["XP_035665277.1","XP_035679909.1",0.539],["XP_035665277.1","XP_035682631.1",0.509],["XP_035665277.1","XP_035683407.1",0.583],["XP_035665277.1","XP_035683836.1",0.661],["XP_035665277.1","XP_035691228.1",0.638],["XP_035665277.1","XP_035691293.1",0.544],["XP_035671555.1","XP_035695995.1",0.56],["XP_035671555.1","XP_035691228.1",0.805],["XP_035671555.1","XP_035691293.1",0.606],["XP_035671555.1","XP_035658585.1",0.631],["XP_035671555.1","XP_035665895.1",0.551],["XP_035671555.1","XP_035668072.1",0.826],["XP_035671555.1","XP_035669493.1",0.661],["XP_035671555.1","XP_035683836.1",0.782],["XP_035671555.1","XP_035683407.1",0.668],["XP_035671555.1","XP_035679909.1",0.535],["XP_035666477.1","XP_035665895.1",0.639],["XP_035666477.1","XP_035668072.1",0.564],["XP_035666477.1","XP_035683836.1",0.724],["XP_035666477.1","XP_035682631.1",0.607],["XP_035666477.1","XP_035679909.1",0.614],["XP_035666477.1","XP_035680054.1",0.552],["XP_035666477.1","XP_035691228.1",0.523],["XP_035683836.1","XP_035679909.1",0.522],["XP_035683836.1","XP_035680054.1",0.609],["XP_035683836.1","XP_035682631.1",0.674],["XP_035683836.1","XP_035691228.1",0.773],["XP_035683836.1","XP_035691293.1",0.815],["XP_035683836.1","XP_035695995.1",0.919],["XP_035683836.1","XP_035657367.1",0.768],["XP_035683836.1","XP_035658585.1",0.654],["XP_035683836.1","XP_035665895.1",0.687],["XP_035683836.1","XP_035668072.1",0.799],["XP_035683836.1","XP_035669493.1",0.698],["XP_035680054.1","XP_035682631.1",0.548],["XP_035680054.1","XP_035691228.1",0.778],["XP_035680054.1","XP_035657367.1",0.55],["XP_035680054.1","XP_035658585.1",0.67],["XP_035680054.1","XP_035669493.1",0.625],["XP_035691228.1","XP_035668072.1",0.82],["XP_035691228.1","XP_035669493.1",0.777],["XP_035691228.1","XP_035682631.1",0.702],["XP_035691228.1","XP_035695995.1",0.824],["XP_035691228.1","XP_035691293.1",0.665],["XP_035691228.1","XP_035657367.1",0.653],["XP_035691228.1","XP_035658585.1",0.69],["XP_035691228.1","XP_035665895.1",0.91],["XP_035669493.1","XP_035695995.1",0.817],["XP_035669493.1","XP_035691293.1",0.749],["XP_035669493.1","XP_035657367.1",0.501],["XP_035669493.1","XP_035658585.1",0.776],["XP_035669493.1","XP_035665895.1",0.641],["XP_035669493.1","XP_035682631.1",0.837],["XP_035669493.1","XP_035683407.1",0.65],["XP_035679909.1","XP_035682631.1",0.791],["XP_035679909.1","XP_035665895.1",0.72],["XP_035691293.1","XP_035682631.1",0.537],["XP_035691293.1","XP_035695995.1",0.595],["XP_035691293.1","XP_035658585.1",0.518],["XP_035665895.1","XP_035657367.1",0.587],["XP_035665895.1","XP_035672024.1",0.526],["XP_035665895.1","XP_035682631.1",0.504],["XP_035665895.1","XP_035695995.1",0.656],["XP_035668072.1","XP_035658585.1",0.779],["XP_035668072.1","XP_035672024.1",0.512],["XP_035668072.1","XP_035682631.1",0.629],["XP_035658585.1","XP_035682631.1",0.521],["XP_035658585.1","XP_035695995.1",0.638],["XP_035695995.1","XP_035682631.1",0.643]],"all_go_terms":{"GO:0007631":1,"GO:0033577":1,"GO:0071793":1,"GO:0019252":1,"GO:0009744":1,"GO:0009405":1,"GO:0009413":1,"GO:0010125":1,"GO:0006506":1,"GO:0005978":1,"GO:0097502":1,"GO:0009247":1,"GO:0008654":1,"GO:0010555":1,"GO:0072708":1,"GO:0006006":2,"GO:0006490":1,"GO:0005985":1,"GO:0009414":1,"GO:0045136":3,"GO:0006029":1,"GO:0018146":3,"GO:0002526":1,"GO:0030879":3,"GO:0008542":1,"GO:0007341":3,"GO:0060046":3,"GO:0048147":3,"GO:0021680":3,"GO:0006688":3,"GO:0060058":3,"GO:0006486":3,"GO:0060055":3,"GO:0005989":3,"GO:0007339":3,"GO:0060054":3,"GO:0075015":8,"GO:0048354":5,"GO:0080147":5,"GO:0010405":5,"GO:0010493":5,"GO:0001744":5,"GO:0007299":5,"GO:0042248":5,"GO:0018258":5,"GO:0030311":5,"GO:0055016":6,"GO:1902367":6,"GO:0045747":6,"GO:0032092":6,"GO:0001541":6,"GO:0007386":6,"GO:0007143":6,"GO:0060576":6,"GO:0016267":6,"GO:0036011":6,"GO:0002315":6,"GO:0009954":2,"GO:0030206":2,"GO:0051923":2,"GO:0060876":2,"GO:0051216":2,"GO:0045880":2,"GO:0046398":2,"GO:0002063":2,"GO:0060349":2,"GO:0050651":2,"GO:0030279":2,"GO:0019276":2,"GO:0050653":2,"GO:0050650":2,"GO:0001958":2,"GO:0050652":2,"GO:0043488":2,"GO:2001153":2,"GO:0039651":1,"GO:0007568":2,"GO:1900087":2,"GO:0045454":2,"GO:0071320":2,"GO:0006308":2,"GO:0006313":2,"GO:0006278":1,"GO:0003335":2,"GO:0006284":2,"GO:0042493":2,"GO:0044179":2,"GO:0006310":2,"GO:0006260":2,"GO:2000327":2,"GO:0070301":2,"GO:0006915":2,"GO:0046856":2,"GO:0080111":2,"GO:0090502":2,"GO:2000466":2,"GO:0046718":1,"GO:1903507":2,"GO:0014912":2,"GO:0071375":2,"GO:1903704":1,"GO:0015074":1,"GO:0075732":1,"GO:0075713":1,"GO:0005975":1,"GO:0006487":1,"GO:0030437":1,"GO:1903501":1,"GO:0031987":1,"GO:0001837":1,"GO:0043029":1,"GO:0010288":1,"GO:0016311":1,"GO:1990918":1,"GO:2000002":1,"GO:0034501":1,"GO:0051531":1,"GO:0009742":1,"GO:0051321":1,"GO:2001241":1,"GO:0010791":1,"GO:0051315":1,"GO:0005981":1,"GO:0042220":1,"GO:1903799":1,"GO:0006986":1,"GO:0072462":1,"GO:0046086":1,"GO:0070940":1,"GO:0036496":1,"GO:0060487":1,"GO:0043278":1,"GO:0030324":1,"GO:0006685":1,"GO:0001569":1,"GO:2001034":1,"GO:0009245":1,"GO:1905205":1,"GO:0014898":1,"GO:0033173":1,"GO:0007498":1,"GO:0050728":1,"GO:0010780":1,"GO:0016576":1,"GO:0060079":1,"GO:0014044":1,"GO:0060316":1,"GO:0051343":1,"GO:0070262":1,"GO:0005979":1,"GO:0099566":1,"GO:0030847":1,"GO:1900486":1,"GO:0014883":1,"GO:0021762":1,"GO:1901901":1,"GO:0006888":1,"GO:0061587":1,"GO:0000903":1,"GO:0010719":1,"GO:0051533":1,"GO:0048741":1,"GO:0097552":1,"GO:0006196":1,"GO:0030846":1,"GO:1903244":1,"GO:0001946":1,"GO:0030182":1,"GO:0098609":1,"GO:0007114":1,"GO:1900490":1,"GO:0032516":1,"GO:0022011":1,"GO:0005513":1,"GO:0000082":1,"GO:0050774":1,"GO:0035753":1,"GO:0035562":1,"GO:0007159":1,"GO:1905213":1,"GO:0035690":1,"GO:0005977":1,"GO:2000324":1,"GO:0031573":1,"GO:0001915":1,"GO:0051037":1,"GO:1902660":1,"GO:0046835":1,"GO:0006000":1,"GO:0006096":1,"GO:0048510":2,"GO:0009908":2,"GO:0009910":2,"GO:0048575":2,"GO:0030154":2,"GO:0010951":2,"GO:0060409":2,"GO:0010229":2,"GO:0009911":2,"GO:0007275":2,"GO:0042755":2,"GO:0048240":2},"recipe_readded":[]}