{"hash":"277961888796619521","title":"Endosomal-Lysosomal Trafficking and Degradation","description":"These proteins cluster around intracellular trafficking routes that move receptors through endosomes to lysosomes, including endosome-to-melanosome transport and lysosomal protein localization, as well as proteolytic processes within vacuoles. The overlap of receptor internalization, endosomal transport, and lysosome-associated degradation supports a cohesive theme of endosomal-lysosomal trafficking and protein turnover.","confidence":"Medium","size":14,"edges":0,"triangles":0,"max_degree":0,"top_function":null,"members":[{"accession":"NP_001348692.1","go_terms":[]},{"accession":"NP_001040806.1","go_terms":["GO:0030886","GO:1901223","GO:0007166","GO:0030913","GO:0046813","GO:0045747","GO:0043128","GO:0014005","GO:0035646","GO:2001046","GO:0007601","GO:1904352","GO:0061462","GO:0060219","GO:2000680","GO:0061298","GO:0031623","GO:0071404","GO:0090528","GO:2000145","GO:1900746"]},{"accession":"NP_001033465.1","go_terms":[]},{"accession":"NP_001300204.1","go_terms":[]},{"accession":"NP_001033369.1","go_terms":[]},{"accession":"NP_001254461.1","go_terms":["GO:0033617"]},{"accession":"NP_001257275.1","go_terms":[]},{"accession":"NP_491720.2","go_terms":[]},{"accession":"NP_492740.1","go_terms":[]},{"accession":"NP_001293956.1","go_terms":["GO:0016024","GO:0060217","GO:0036149"]},{"accession":"NP_001033493.1","go_terms":[]},{"accession":"NP_001024809.1","go_terms":[]},{"accession":"NP_001379408.1","go_terms":["GO:0006888","GO:2000269"]},{"accession":"NP_001380086.1","go_terms":["GO:0051384","GO:0015705","GO:2000463","GO:0097091","GO:0001507","GO:0061002","GO:2000809","GO:0010841","GO:0060041","GO:0002087","GO:0097104","GO:0042982","GO:0098942","GO:2000310","GO:0014016","GO:0048789","GO:0042136","GO:1900244","GO:0051262","GO:0016042","GO:0050783","GO:0007612","GO:0008285","GO:1902474","GO:2000331","GO:0002076","GO:0051593","GO:0045212","GO:1904862","GO:1904861","GO:0043279","GO:2000969","GO:0097105","GO:0001919","GO:0097151","GO:0032223","GO:0031623","GO:0009740","GO:0090394","GO:0019695","GO:0072553","GO:0042493","GO:2000302","GO:0097115","GO:0097116","GO:0051968","GO:0097119","GO:0007158"]}],"graph":[],"all_go_terms":{"GO:0035646":1,"GO:0007601":1,"GO:0031623":2,"GO:0030886":1,"GO:1900746":1,"GO:0030913":1,"GO:2000680":1,"GO:0071404":1,"GO:0061462":1,"GO:1904352":1,"GO:2000145":1,"GO:0014005":1,"GO:0045747":1,"GO:0060219":1,"GO:1901223":1,"GO:0007166":1,"GO:0046813":1,"GO:0043128":1,"GO:0061298":1,"GO:2001046":1,"GO:0090528":1,"GO:0033617":1,"GO:0036149":1,"GO:0060217":1,"GO:0016024":1,"GO:2000269":1,"GO:0006888":1,"GO:1902474":1,"GO:0042982":1,"GO:0060041":1,"GO:0015705":1,"GO:0042136":1,"GO:0007612":1,"GO:0097091":1,"GO:0019695":1,"GO:2000809":1,"GO:0097116":1,"GO:2000463":1,"GO:0072553":1,"GO:2000331":1,"GO:1904862":1,"GO:0051593":1,"GO:0008285":1,"GO:0050783":1,"GO:0097151":1,"GO:0001919":1,"GO:1904861":1,"GO:1900244":1,"GO:0010841":1,"GO:0016042":1,"GO:0045212":1,"GO:0090394":1,"GO:0014016":1,"GO:0007158":1,"GO:0098942":1,"GO:0048789":1,"GO:0002087":1,"GO:0097104":1,"GO:0051262":1,"GO:2000302":1,"GO:0051384":1,"GO:0097115":1,"GO:0002076":1,"GO:0001507":1,"GO:0097105":1,"GO:2000969":1,"GO:0061002":1,"GO:0042493":1,"GO:0051968":1,"GO:0097119":1,"GO:0009740":1,"GO:2000310":1,"GO:0043279":1,"GO:0032223":1},"recipe_readded":["NP_006959.1","NP_001379864.1","NP_001379575.1","NP_001379574.1","NP_001431089.1","NP_001379137.1","NP_001022930.1"]}