{"hash":"2210819172131845300","title":"Embryonic organogenesis and TGF-beta signaling","description":"Based on the top GO terms, the proteins cluster around developmental processes such as metanephric kidney development, blastocyst formation, and endocardial cushion EMT, as well as cell-matrix adhesion and vascular development, all of which are morphogenetic events in embryogenesis. The presence of TGF-beta receptor complex assembly further suggests a shared signaling axis governing these organogenesis-related processes. Immune terms are present but less cohesive with the core developmental theme, and may reflect secondary roles or incidental connections. Overall, the cluster seems best described as embryonic organogenesis guided by TGF-beta signaling.","confidence":"Medium","size":13,"edges":20,"triangles":2,"max_degree":7,"top_function":null,"members":[{"accession":"NP_001294420.1","go_terms":[]},{"accession":"NP_001022161.1","go_terms":[]},{"accession":"NP_872256.1","go_terms":[]},{"accession":"NP_001300406.1","go_terms":[]},{"accession":"NP_505091.1","go_terms":[]},{"accession":"NP_001379066.1","go_terms":["GO:2000368","GO:2000360","GO:0015768","GO:0031953","GO:0007160","GO:0002922","GO:0003273","GO:0061384","GO:0032729","GO:0002455","GO:0072233","GO:0072221","GO:0032354","GO:0090280","GO:0040005","GO:0001825","GO:0048845","GO:0034695","GO:0060468","GO:0055009","GO:0034699","GO:0007181","GO:0001809","GO:0003198","GO:0035912","GO:0048599","GO:0007605","GO:0003391","GO:1903118","GO:0048745","GO:0097084","GO:0042102","GO:1905065","GO:0007339","GO:1905222","GO:1905007","GO:0022009","GO:0072218","GO:0097211","GO:0035889","GO:2000388","GO:0060478","GO:0032753","GO:0035803","GO:0010513","GO:0060389"]},{"accession":"NP_001076644.1","go_terms":[]},{"accession":"NP_496506.1","go_terms":[]},{"accession":"NP_504043.2","go_terms":[]},{"accession":"NP_506503.1","go_terms":[]},{"accession":"NP_001033410.1","go_terms":[]},{"accession":"NP_001303804.1","go_terms":[]},{"accession":"NP_001355377.1","go_terms":[]}],"graph":[["NP_001022161.1","NP_001294420.1",0.838],["NP_001022161.1","NP_496506.1",0.886],["NP_001379066.1","NP_505091.1",0.859],["NP_001379066.1","NP_506503.1",0.869],["NP_001379066.1","NP_496506.1",0.946],["NP_496506.1","NP_001033410.1",0.712],["NP_496506.1","NP_001076644.1",0.915],["NP_496506.1","NP_001300406.1",0.807],["NP_496506.1","NP_001303804.1",0.931],["NP_496506.1","NP_001355377.1",0.775],["NP_001294420.1","NP_001033410.1",0.82],["NP_001294420.1","NP_001300406.1",0.769],["NP_001294420.1","NP_872256.1",0.942],["NP_001294420.1","NP_506503.1",0.914],["NP_001294420.1","NP_505091.1",0.811],["NP_001294420.1","NP_504043.2",0.795],["NP_001300406.1","NP_505091.1",0.833],["NP_001300406.1","NP_872256.1",0.743],["NP_505091.1","NP_001076644.1",0.82],["NP_872256.1","NP_001076644.1",0.605]],"all_go_terms":{"GO:0072233":1,"GO:0001825":1,"GO:0002455":1,"GO:0072221":1,"GO:0007181":1,"GO:0022009":1,"GO:0001809":1,"GO:0042102":1,"GO:0007160":1,"GO:0003198":1,"GO:0002922":1,"GO:0048745":1,"GO:0048845":1,"GO:0032729":1,"GO:0007339":1,"GO:0097084":1,"GO:0061384":1,"GO:1905065":1,"GO:0034695":1,"GO:0055009":1,"GO:0032354":1,"GO:0060468":1,"GO:0097211":1,"GO:0072218":1,"GO:0060478":1,"GO:0007605":1,"GO:0060389":1,"GO:1903118":1,"GO:0035912":1,"GO:2000388":1,"GO:0090280":1,"GO:0031953":1,"GO:0035803":1,"GO:0035889":1,"GO:0040005":1,"GO:1905222":1,"GO:0003273":1,"GO:0048599":1,"GO:1905007":1,"GO:2000368":1,"GO:0015768":1,"GO:0032753":1,"GO:0003391":1,"GO:0010513":1,"GO:2000360":1,"GO:0034699":1},"recipe_readded":[]}