{"hash":"276773871917543178","title":"Proteostasis and Protein Processing","description":"The cluster is dominated by GO terms for protein degradation and processing (proteasome regulatory particle assembly; protein catabolic process), with supporting terms for post-translational modification (glycosylation; poly-ADP-ribosylation) and protein trafficking (maintenance of protein localization in the plasma membrane). Some included terms (heart morphogenesis, pain sensing) appear peripheral or noisy, but the core theme centers on proteostasis and protein maturation/trafficking.","confidence":"Medium","size":15,"edges":51,"triangles":71,"max_degree":12,"top_function":null,"members":[{"accession":"XP_002808792.1","go_terms":["GO:0006487"]},{"accession":"XP_002809011.1","go_terms":["GO:0090501","GO:0051017","GO:0032212","GO:0051225","GO:0006397","GO:0050960","GO:0050968","GO:0007205","GO:0071260","GO:0070213","GO:0043403","GO:1901187","GO:0035556","GO:0021707","GO:0071901","GO:0002268","GO:0016049","GO:0007253","GO:0090162","GO:2000031","GO:2000171","GO:1903589","GO:0016477","GO:0097284","GO:0070682","GO:1900383","GO:0035994","GO:0035508","GO:0033280","GO:0098703","GO:1901594","GO:0045083","GO:0009408","GO:0003213","GO:0044707","GO:0016055","GO:0003270","GO:0016567","GO:0071446","GO:0033028","GO:0046475","GO:0060843","GO:0061408","GO:1904355","GO:0072660","GO:0070212","GO:1900827","GO:0010845","GO:1904743","GO:1904908","GO:0010650","GO:0070198","GO:0048709","GO:0045736","GO:0007049","GO:2000340","GO:0050966","GO:0000083","GO:0045038","GO:0045444","GO:0097497","GO:0051209","GO:1903759","GO:0048265","GO:0043488","GO:0070431","GO:0071642","GO:0098907","GO:0010745","GO:1903444","GO:0050955","GO:1904357","GO:0060743","GO:0035544","GO:0009409","GO:0086070","GO:0032088","GO:0030103","GO:0070427","GO:0071651","GO:0048549","GO:2001275"]},{"accession":"XP_024328969.1","go_terms":[]},{"accession":"XP_002808907.1","go_terms":[]},{"accession":"XP_002808690.1","go_terms":[]},{"accession":"XP_002809094.1","go_terms":[]},{"accession":"XP_001350619.1","go_terms":[]},{"accession":"XP_001348621.2","go_terms":["GO:0017186"]},{"accession":"XP_001351277.1","go_terms":["GO:0045047","GO:0006465"]},{"accession":"XP_001348251.1","go_terms":["GO:0009627","GO:0030163","GO:0045493","GO:0006508","GO:0002803","GO:0007586","GO:0019886","GO:0002018","GO:0016540","GO:0001823","GO:0002003","GO:0033619","GO:0070305","GO:0042985","GO:0042756","GO:0002016","GO:0050435"]},{"accession":"XP_002808786.1","go_terms":[]},{"accession":"XP_001350553.1","go_terms":[]},{"accession":"XP_001347874.1","go_terms":["GO:0061738","GO:0031117","GO:0051260","GO:0030420","GO:2001171","GO:0034214","GO:1903862","GO:0032968","GO:0070842","GO:0001824","GO:0006260","GO:0034551","GO:0070682","GO:0033314","GO:0032979","GO:0051013","GO:0046034","GO:1901800","GO:1990171","GO:0016485","GO:0045899","GO:0030968","GO:0006272","GO:0070987","GO:0043335","GO:0070676","GO:0070370","GO:1903007","GO:0090261","GO:0070914","GO:0061641","GO:0061166","GO:1903715","GO:0051301","GO:0006888","GO:0045053","GO:0001319","GO:0035494","GO:0019079","GO:0070414","GO:0097352","GO:0071218","GO:0016562","GO:2000158","GO:0070389","GO:0018279","GO:0006406","GO:0051131","GO:0048219","GO:0030433","GO:1903724","GO:0034599","GO:0090296","GO:0072389","GO:0045041","GO:0016558","GO:0000733","GO:0070407","GO:0070651","GO:0071712","GO:0035617","GO:0010205","GO:0010206","GO:0010304","GO:0030150","GO:0006515","GO:0060013","GO:0030163"]},{"accession":"XP_001347415.1","go_terms":[]},{"accession":"XP_966099.2","go_terms":["GO:0044339","GO:0000022"]}],"graph":[["XP_002808907.1","XP_001347415.1",0.605],["XP_002808907.1","XP_001350619.1",0.711],["XP_002808907.1","XP_002808690.1",0.799],["XP_002808907.1","XP_002808792.1",0.642],["XP_002808907.1","XP_002809094.1",0.528],["XP_001348251.1","XP_024328969.1",0.596],["XP_001348251.1","XP_002808786.1",0.544],["XP_001348251.1","XP_001351277.1",0.671],["XP_001348251.1","XP_001348621.2",0.793],["XP_001348621.2","XP_001347874.1",0.579],["XP_001348621.2","XP_001350553.1",0.83],["XP_001348621.2","XP_002808792.1",0.825],["XP_001348621.2","XP_002809094.1",0.506],["XP_001348621.2","XP_024328969.1",0.52],["XP_001348621.2","XP_966099.2",0.747],["XP_001347415.1","XP_001350553.1",0.545],["XP_001347415.1","XP_002808690.1",0.588],["XP_001347415.1","XP_002808786.1",0.605],["XP_001347415.1","XP_002808792.1",0.54],["XP_001347415.1","XP_024328969.1",0.849],["XP_002808786.1","XP_001347874.1",0.743],["XP_002808786.1","XP_001350553.1",0.542],["XP_002808786.1","XP_001350619.1",0.506],["XP_002808786.1","XP_001351277.1",0.635],["XP_002808786.1","XP_002808690.1",0.84],["XP_002808786.1","XP_002808792.1",0.729],["XP_002808786.1","XP_002809094.1",0.701],["XP_002808786.1","XP_024328969.1",0.719],["XP_002808786.1","XP_966099.2",0.609],["XP_002809011.1","XP_001350619.1",0.567],["XP_002808690.1","XP_001350619.1",0.71],["XP_002808690.1","XP_001351277.1",0.658],["XP_002808690.1","XP_002808792.1",0.503],["XP_002808690.1","XP_002809094.1",0.535],["XP_002808690.1","XP_024328969.1",0.58],["XP_002808690.1","XP_966099.2",0.625],["XP_001351277.1","XP_002808792.1",0.718],["XP_001351277.1","XP_002809094.1",0.605],["XP_001351277.1","XP_024328969.1",0.71],["XP_001351277.1","XP_966099.2",0.773],["XP_966099.2","XP_002808792.1",0.674],["XP_966099.2","XP_024328969.1",0.554],["XP_001350619.1","XP_002808792.1",0.683],["XP_001350619.1","XP_002809094.1",0.726],["XP_001347874.1","XP_002808792.1",0.604],["XP_001347874.1","XP_002809094.1",0.5],["XP_001347874.1","XP_001350553.1",0.571],["XP_002808792.1","XP_001350553.1",0.625],["XP_002808792.1","XP_002809094.1",0.611],["XP_002808792.1","XP_024328969.1",0.731],["XP_024328969.1","XP_002809094.1",0.782]],"all_go_terms":{"GO:0006487":1,"GO:0070427":1,"GO:0000083":1,"GO:0070212":1,"GO:0003213":1,"GO:0044707":1,"GO:0050968":1,"GO:0072660":1,"GO:0090162":1,"GO:1904355":1,"GO:0033280":1,"GO:0021707":1,"GO:0048549":1,"GO:0090501":1,"GO:0006397":1,"GO:0007205":1,"GO:0071260":1,"GO:0071446":1,"GO:0035508":1,"GO:0050966":1,"GO:0051209":1,"GO:0043488":1,"GO:2000171":1,"GO:0010845":1,"GO:0098703":1,"GO:0050960":1,"GO:0071642":1,"GO:0032212":1,"GO:0035556":1,"GO:0051225":1,"GO:0098907":1,"GO:1901594":1,"GO:0051017":1,"GO:0016477":1,"GO:0009409":1,"GO:0048709":1,"GO:0016055":1,"GO:1904908":1,"GO:0045038":1,"GO:0010745":1,"GO:1901187":1,"GO:0043403":1,"GO:0046475":1,"GO:0016567":1,"GO:1903759":1,"GO:0030103":1,"GO:0070431":1,"GO:0070682":2,"GO:0045444":1,"GO:0071651":1,"GO:0086070":1,"GO:2000340":1,"GO:1903444":1,"GO:0009408":1,"GO:0016049":1,"GO:0010650":1,"GO:2000031":1,"GO:0045736":1,"GO:0035544":1,"GO:0007253":1,"GO:0003270":1,"GO:0071901":1,"GO:0060743":1,"GO:1900827":1,"GO:0097497":1,"GO:0033028":1,"GO:0050955":1,"GO:2001275":1,"GO:0045083":1,"GO:0035994":1,"GO:0061408":1,"GO:1904743":1,"GO:1903589":1,"GO:0070213":1,"GO:0070198":1,"GO:1904357":1,"GO:0048265":1,"GO:0032088":1,"GO:1900383":1,"GO:0007049":1,"GO:0097284":1,"GO:0060843":1,"GO:0002268":1,"GO:0017186":1,"GO:0006465":1,"GO:0045047":1,"GO:0019886":1,"GO:0042985":1,"GO:0030163":2,"GO:0042756":1,"GO:0002803":1,"GO:0002018":1,"GO:0006508":1,"GO:0002003":1,"GO:0016540":1,"GO:0002016":1,"GO:0050435":1,"GO:0033619":1,"GO:0070305":1,"GO:0001823":1,"GO:0007586":1,"GO:0045493":1,"GO:0009627":1,"GO:0033314":1,"GO:0030433":1,"GO:0034214":1,"GO:0006272":1,"GO:0032979":1,"GO:0045899":1,"GO:0061641":1,"GO:0035617":1,"GO:1990171":1,"GO:0016562":1,"GO:0071712":1,"GO:0043335":1,"GO:0070407":1,"GO:0060013":1,"GO:0010205":1,"GO:0070370":1,"GO:0031117":1,"GO:0030968":1,"GO:0090261":1,"GO:1903862":1,"GO:0051301":1,"GO:0051260":1,"GO:0034551":1,"GO:0006406":1,"GO:0000733":1,"GO:0097352":1,"GO:0019079":1,"GO:0070414":1,"GO:0016558":1,"GO:0010206":1,"GO:0061738":1,"GO:0051131":1,"GO:0034599":1,"GO:0070914":1,"GO:0070651":1,"GO:0071218":1,"GO:0006515":1,"GO:0001824":1,"GO:0035494":1,"GO:1903007":1,"GO:0006888":1,"GO:1901800":1,"GO:0070389":1,"GO:1903724":1,"GO:0001319":1,"GO:0070842":1,"GO:0051013":1,"GO:0090296":1,"GO:0072389":1,"GO:0030150":1,"GO:0046034":1,"GO:0045053":1,"GO:0045041":1,"GO:0061166":1,"GO:2000158":1,"GO:0030420":1,"GO:2001171":1,"GO:0048219":1,"GO:1903715":1,"GO:0032968":1,"GO:0016485":1,"GO:0018279":1,"GO:0010304":1,"GO:0070676":1,"GO:0006260":1,"GO:0070987":1,"GO:0000022":1,"GO:0044339":1},"recipe_readded":[]}