{"hash":"1515130060705746760","title":"Ubiquitin-Proteasome Mediated Protein Degradation","description":"The top terms cluster around ubiquitin-dependent processes: SCF complex assembly, K11- and K48-linked ubiquitination, ubiquitin-dependent protein catabolic process, and ubiquitin-dependent ERAD, all pointing to proteostasis through targeted protein degradation. Although other terms touch on DNA repair or growth regulation, the dominant theme is proteolysis mediated by ubiquitin pathways.","confidence":"High","size":3,"edges":1,"triangles":0,"max_degree":1,"top_function":null,"members":[{"accession":"XP_001351261.1","go_terms":["GO:0038018","GO:0016558","GO:0030433","GO:0060816","GO:0051865","GO:0042787","GO:0046621","GO:1900095","GO:0070936","GO:0006295","GO:0006294","GO:0006296","GO:0045116","GO:0010265","GO:0043162","GO:0000717","GO:0006293","GO:0000715","GO:0016567","GO:1902104","GO:0042769","GO:0016032","GO:0051759","GO:0031146","GO:0070911","GO:0070979","GO:0031145","GO:0051301"]},{"accession":"XP_966227.1","go_terms":["GO:0038018","GO:0016558","GO:0030433","GO:0060816","GO:0051865","GO:0042787","GO:0046621","GO:1900095","GO:0070936","GO:0006295","GO:0006294","GO:0006296","GO:0045116","GO:0010265","GO:0043162","GO:0000717","GO:0006293","GO:0000715","GO:0016567","GO:1902104","GO:0042769","GO:0016032","GO:0051759","GO:0031146","GO:0070911","GO:0070979","GO:0031145","GO:0051301"]},{"accession":"XP_001351831.1","go_terms":[]}],"graph":[["XP_001351261.1","XP_966227.1",0.705]],"all_go_terms":{"GO:0000717":2,"GO:0030433":2,"GO:0046621":2,"GO:0000715":2,"GO:0070979":2,"GO:0060816":2,"GO:0042787":2,"GO:0051301":2,"GO:0070936":2,"GO:0010265":2,"GO:0051759":2,"GO:0016558":2,"GO:0006295":2,"GO:0042769":2,"GO:0016032":2,"GO:0031145":2,"GO:0070911":2,"GO:0031146":2,"GO:0038018":2,"GO:0006293":2,"GO:1902104":2,"GO:0016567":2,"GO:0045116":2,"GO:0006296":2,"GO:0006294":2,"GO:0043162":2,"GO:1900095":2,"GO:0051865":2},"recipe_readded":["XP_001348502.1","XP_001349359.1","XP_001350519.1","XP_001350093.1","XP_001348670.1","XP_001352124.1","XP_024328874.1","XP_002808862.1","XP_001351761.1","XP_001351504.1","XP_001349440.1","XP_001348003.1","XP_001350359.1","XP_001347842.1","XP_001351213.1","XP_002809084.1","XP_001348002.1","XP_001350691.1","XP_001352147.1","XP_001350840.1"]}