{"hash":"1328775935061387118","title":"ER Proteostasis and Unfolded Protein Response","description":"These proteins cluster around endoplasmic reticulum\u2013associated proteostasis: protein folding in the ER, response to unfolded proteins, ERAD/ubiquitin-proteasome quality control, and ER stress\u2013driven regulation of translation. A few developmental terms are present but do not define the main theme, which is ER protein folding and degradation pathways.","confidence":"High","size":3,"edges":2,"triangles":0,"max_degree":2,"top_function":null,"members":[{"accession":"XP_001682254.1","go_terms":["GO:0006452","GO:0090084","GO:0006458","GO:0031204","GO:0006986","GO:0071374","GO:0001707","GO:0070843","GO:1901621","GO:0006260","GO:0070389","GO:0097428","GO:0006469","GO:0032781","GO:0006626","GO:0030433","GO:0009408","GO:0045454","GO:0036494","GO:0051259","GO:1900035","GO:0046825","GO:0035719","GO:0071630","GO:0034975"]},{"accession":"XP_001686031.1","go_terms":["GO:0006452","GO:0090084","GO:0006458","GO:0031204","GO:0006986","GO:0071374","GO:0001707","GO:0070843","GO:1901621","GO:0006260","GO:0070389","GO:0097428","GO:0006469","GO:0032781","GO:0006626","GO:0030433","GO:0009408","GO:0045454","GO:0036494","GO:0051259","GO:1900035","GO:0046825","GO:0035719","GO:0071630","GO:0034975"]},{"accession":"XP_001683945.1","go_terms":["GO:0010206"]}],"graph":[["XP_001686031.1","XP_001682254.1",0.836],["XP_001682254.1","XP_001683945.1",0.535]],"all_go_terms":{"GO:1901621":2,"GO:0034975":2,"GO:0006986":2,"GO:0001707":2,"GO:0032781":2,"GO:0030433":2,"GO:0006626":2,"GO:0035719":2,"GO:0036494":2,"GO:0071630":2,"GO:0006469":2,"GO:0070389":2,"GO:0006260":2,"GO:0045454":2,"GO:0051259":2,"GO:0070843":2,"GO:0006458":2,"GO:0009408":2,"GO:0006452":2,"GO:1900035":2,"GO:0046825":2,"GO:0031204":2,"GO:0090084":2,"GO:0097428":2,"GO:0071374":2,"GO:0010206":1},"recipe_readded":[]}