{"hash":"1012726436980300713","title":"Neuron maturation linked to ubiquitin-proteasome and mitochondria","description":"The top GO terms cluster around ubiquitin-related proteostasis (monoubiquitination, autoubiquitination, proteasomal degradation) and mitochondrial regulation (membrane potential, ATP synthesis, cytochrome c release), alongside neuron maturation. This suggests a coordinated program in developing neurons that ties protein turnover to mitochondrial health to support maturation and anti-apoptotic stability. ","confidence":"Medium","size":13,"edges":7,"triangles":0,"max_degree":6,"top_function":null,"members":[{"accession":"XP_001684822.1","go_terms":["GO:0035774","GO:0000423","GO:0032436","GO:0000266","GO:0099074","GO:0090201","GO:0033132","GO:0051865","GO:0043388","GO:0051583","GO:0036205","GO:0051412","GO:0023035","GO:0046329","GO:1903265","GO:0070936","GO:0090258","GO:0006986","GO:0070842","GO:0070979","GO:0048078","GO:0090141","GO:0010918","GO:0085020","GO:0042787","GO:1902283","GO:0071287","GO:1903427","GO:0070534","GO:0043123","GO:0060546","GO:0010636","GO:1903382","GO:2001171","GO:1902530","GO:0055069","GO:1905366","GO:0008344","GO:1903542","GO:0097039","GO:0010637","GO:0090394","GO:1904049","GO:0097237","GO:0042551","GO:0070050","GO:0006513","GO:1903378","GO:0051967","GO:0006351","GO:1903377","GO:0046676"]},{"accession":"XP_001681494.1","go_terms":[]},{"accession":"XP_001684478.1","go_terms":["GO:0070125","GO:0045901","GO:0017183","GO:0014009","GO:1990145","GO:0002244","GO:1902802","GO:1990416","GO:0035914","GO:2000767","GO:0032790","GO:0032543","GO:0003009","GO:0000388","GO:0000349","GO:0000244","GO:0006412","GO:0001514","GO:0046677","GO:0000288","GO:0006413","GO:0006415"]},{"accession":"XP_001681083.1","go_terms":[]},{"accession":"XP_001682224.1","go_terms":[]},{"accession":"XP_001684107.1","go_terms":[]},{"accession":"XP_001683947.1","go_terms":["GO:0032511","GO:0060400","GO:2000009"]},{"accession":"XP_003721830.1","go_terms":[]},{"accession":"XP_001681011.2","go_terms":[]},{"accession":"XP_003722558.1","go_terms":["GO:0006457","GO:0006298","GO:0000713","GO:0000710","GO:0051257","GO:0007060","GO:0043060","GO:0007131","GO:0007144","GO:0016446"]},{"accession":"XP_001681811.1","go_terms":["GO:0050766","GO:0006888"]},{"accession":"XP_001682031.1","go_terms":[]},{"accession":"XP_001681004.1","go_terms":[]}],"graph":[["XP_001684822.1","XP_001683947.1",0.545],["XP_001681004.1","XP_003722558.1",0.677],["XP_001681811.1","XP_003722558.1",0.61],["XP_001683947.1","XP_003722558.1",0.76],["XP_003721830.1","XP_003722558.1",0.66],["XP_001681011.2","XP_003722558.1",0.502],["XP_001682031.1","XP_003722558.1",0.528]],"all_go_terms":{"GO:0036205":1,"GO:0006513":1,"GO:0090201":1,"GO:0032436":1,"GO:0051865":1,"GO:0042551":1,"GO:0010918":1,"GO:1905366":1,"GO:1903377":1,"GO:2001171":1,"GO:1903378":1,"GO:0090258":1,"GO:0006986":1,"GO:0070936":1,"GO:0042787":1,"GO:0099074":1,"GO:0051583":1,"GO:0043388":1,"GO:0033132":1,"GO:0070050":1,"GO:1903427":1,"GO:0000423":1,"GO:1903542":1,"GO:0090141":1,"GO:0097237":1,"GO:1903382":1,"GO:0000266":1,"GO:0070842":1,"GO:0070979":1,"GO:1903265":1,"GO:1902530":1,"GO:0060546":1,"GO:0010636":1,"GO:0010637":1,"GO:1902283":1,"GO:0043123":1,"GO:1904049":1,"GO:0046329":1,"GO:0048078":1,"GO:0023035":1,"GO:0046676":1,"GO:0051967":1,"GO:0035774":1,"GO:0097039":1,"GO:0008344":1,"GO:0006351":1,"GO:0055069":1,"GO:0071287":1,"GO:0090394":1,"GO:0085020":1,"GO:0070534":1,"GO:0051412":1,"GO:0000288":1,"GO:0070125":1,"GO:1902802":1,"GO:0006413":1,"GO:0032790":1,"GO:0017183":1,"GO:0000349":1,"GO:0000388":1,"GO:1990145":1,"GO:1990416":1,"GO:0014009":1,"GO:0032543":1,"GO:0006412":1,"GO:0046677":1,"GO:0006415":1,"GO:0002244":1,"GO:0000244":1,"GO:2000767":1,"GO:0003009":1,"GO:0001514":1,"GO:0045901":1,"GO:0035914":1,"GO:0060400":1,"GO:2000009":1,"GO:0032511":1,"GO:0000713":1,"GO:0051257":1,"GO:0006298":1,"GO:0006457":1,"GO:0000710":1,"GO:0007144":1,"GO:0007060":1,"GO:0016446":1,"GO:0007131":1,"GO:0043060":1,"GO:0006888":1,"GO:0050766":1},"recipe_readded":["XP_001686912.1","XP_003722419.1","XP_001683923.1","XP_001682079.1","XP_001681121.1","XP_001684996.1","XP_001686915.1","XP_003722546.1","XP_001685329.1","XP_001685704.1","XP_003722109.1","XP_001681874.1","XP_001686396.1","XP_001682809.1","XP_001685809.1","XP_001686329.1","XP_001686917.1","XP_001681124.1","XP_001684666.1","XP_001687180.1"]}