{"hash":"975025951435321561","title":"Nuclear RNA processing and chromatin regulation","description":"This cluster is dominated by terms tied to RNA processing in the nucleus (transcription termination, spliceosome assembly, mRNA splicing, deadenylation-dependent decapping, histone mRNA metabolism) along with chromatin-related processes (pericentric heterochromatin formation). The co-occurrence of splicing and RNA decay with chromatin maintenance suggests proteins functioning at the intersection of RNA processing and chromatin regulation, rather than disparate roles. Confidence that this label captures the core function is High.","confidence":"","size":14,"edges":90,"triangles":352,"max_degree":13,"top_function":null,"members":[{"accession":"NP_904228.1","go_terms":["GO:0032986","GO:0071158","GO:0072717","GO:2000059","GO:0050821","GO:1904667","GO:1901798","GO:0006412","GO:0071157"]},{"accession":"XP_024402792.1","go_terms":["GO:0034724","GO:0030574","GO:0034396","GO:0035551"]},{"accession":"XP_024379839.1","go_terms":["GO:0042254","GO:0001172","GO:0006360","GO:0006366","GO:0006386","GO:0006385","GO:0042797"]},{"accession":"XP_024403205.1","go_terms":["GO:0034724","GO:0030574","GO:0034396","GO:0035551"]},{"accession":"XP_073386458.1","go_terms":["GO:0008033","GO:0033962","GO:0008334","GO:0070317","GO:0051170","GO:1990141","GO:0009414","GO:0042633","GO:0000245","GO:0000387","GO:0000290","GO:0009737","GO:0030490","GO:0006369","GO:0045292"]},{"accession":"XP_024360410.1","go_terms":["GO:0008033","GO:0033962","GO:0008334","GO:0070317","GO:0051170","GO:1990141","GO:0009414","GO:0042633","GO:0000245","GO:0000387","GO:0000290","GO:0009737","GO:0030490","GO:0006369","GO:0045292"]},{"accession":"XP_024360088.1","go_terms":[]},{"accession":"XP_024360411.1","go_terms":["GO:0008033","GO:0033962","GO:0008334","GO:0070317","GO:0051170","GO:1990141","GO:0009414","GO:0042633","GO:0000245","GO:0000387","GO:0000290","GO:0009737","GO:0030490","GO:0006369","GO:0045292"]},{"accession":"XP_024394039.1","go_terms":["GO:0008033","GO:0033962","GO:0008334","GO:0070317","GO:0051170","GO:1990141","GO:0009414","GO:0042633","GO:0000245","GO:0000387","GO:0000290","GO:0009737","GO:0030490","GO:0006369","GO:0045292"]},{"accession":"XP_024367304.1","go_terms":["GO:0008033","GO:0033962","GO:0008334","GO:0070317","GO:0051170","GO:1990141","GO:0009414","GO:0042633","GO:0000245","GO:0000387","GO:0000290","GO:0009737","GO:0030490","GO:0006369","GO:0045292","GO:0010603","GO:0002091","GO:0042051","GO:0009994","GO:0097167","GO:0034063","GO:1905833","GO:0060965","GO:1904780","GO:0043007","GO:0046959","GO:0051823","GO:0090328","GO:0022416"]},{"accession":"XP_024391593.1","go_terms":["GO:0008033","GO:0033962","GO:0008334","GO:0070317","GO:0051170","GO:1990141","GO:0009414","GO:0042633","GO:0000245","GO:0000387","GO:0000290","GO:0009737","GO:0030490","GO:0006369","GO:0045292"]},{"accession":"XP_024375304.1","go_terms":["GO:0008033","GO:0033962","GO:0008334","GO:0070317","GO:0051170","GO:1990141","GO:0009414","GO:0042633","GO:0000245","GO:0000387","GO:0000290","GO:0009737","GO:0030490","GO:0006369","GO:0045292"]},{"accession":"XP_024375286.1","go_terms":["GO:0008033","GO:0033962","GO:0008334","GO:0070317","GO:0051170","GO:1990141","GO:0009414","GO:0042633","GO:0000245","GO:0000387","GO:0000290","GO:0009737","GO:0030490","GO:0006369","GO:0045292"]},{"accession":"XP_024359140.1","go_terms":["GO:0008033","GO:0033962","GO:0008334","GO:0070317","GO:0051170","GO:1990141","GO:0009414","GO:0042633","GO:0000245","GO:0000387","GO:0000290","GO:0009737","GO:0030490","GO:0006369","GO:0045292"]}],"graph":[["XP_024403205.1","XP_024375286.1",0.962],["XP_024403205.1","XP_024375304.1",0.985],["XP_024403205.1","XP_024379839.1",0.967],["XP_024403205.1","XP_024391593.1",0.965],["XP_024403205.1","XP_024394039.1",0.969],["XP_024403205.1","XP_024402792.1",0.96],["XP_024403205.1","XP_073386458.1",0.959],["XP_024403205.1","NP_904228.1",0.979],["XP_024403205.1","XP_024359140.1",0.982],["XP_024403205.1","XP_024360088.1",0.96],["XP_024403205.1","XP_024360410.1",0.982],["XP_024403205.1","XP_024360411.1",0.968],["XP_024403205.1","XP_024367304.1",0.974],["XP_024367304.1","NP_904228.1",0.503],["XP_024367304.1","XP_024359140.1",0.56],["XP_024367304.1","XP_024360088.1",0.902],["XP_024367304.1","XP_024360410.1",0.922],["XP_024367304.1","XP_024360411.1",0.805],["XP_024367304.1","XP_024375286.1",0.89],["XP_024367304.1","XP_024379839.1",0.946],["XP_024367304.1","XP_024391593.1",0.643],["XP_024367304.1","XP_024394039.1",0.828],["XP_024367304.1","XP_024402792.1",0.971],["XP_024367304.1","XP_073386458.1",0.799],["XP_024394039.1","XP_024379839.1",0.94],["XP_024394039.1","XP_024391593.1",0.857],["XP_024394039.1","XP_073386458.1",0.915],["XP_024394039.1","XP_024402792.1",0.95],["XP_024394039.1","NP_904228.1",0.805],["XP_024394039.1","XP_024359140.1",0.877],["XP_024394039.1","XP_024360088.1",0.938],["XP_024394039.1","XP_024360410.1",0.951],["XP_024394039.1","XP_024360411.1",0.921],["XP_024394039.1","XP_024375286.1",0.903],["XP_024394039.1","XP_024375304.1",0.862],["NP_904228.1","XP_024359140.1",0.547],["NP_904228.1","XP_024360088.1",0.874],["NP_904228.1","XP_024360410.1",0.899],["NP_904228.1","XP_024360411.1",0.755],["NP_904228.1","XP_024375286.1",0.867],["NP_904228.1","XP_024375304.1",0.541],["NP_904228.1","XP_024379839.1",0.968],["NP_904228.1","XP_024391593.1",0.68],["NP_904228.1","XP_024402792.1",0.967],["NP_904228.1","XP_073386458.1",0.819],["XP_024360410.1","XP_024359140.1",0.93],["XP_024360410.1","XP_024360088.1",0.952],["XP_024360410.1","XP_024360411.1",0.957],["XP_024360410.1","XP_024379839.1",0.966],["XP_024360410.1","XP_024375286.1",0.936],["XP_024360410.1","XP_024375304.1",0.942],["XP_024360410.1","XP_024391593.1",0.944],["XP_024360410.1","XP_073386458.1",0.942],["XP_024360410.1","XP_024402792.1",0.96],["XP_024379839.1","XP_024391593.1",0.952],["XP_024379839.1","XP_073386458.1",0.94],["XP_024379839.1","XP_024402792.1",0.968],["XP_024379839.1","XP_024359140.1",0.963],["XP_024379839.1","XP_024360088.1",0.964],["XP_024379839.1","XP_024360411.1",0.975],["XP_024379839.1","XP_024375286.1",0.948],["XP_024379839.1","XP_024375304.1",0.959],["XP_024391593.1","XP_024402792.1",0.97],["XP_024391593.1","XP_073386458.1",0.897],["XP_024391593.1","XP_024359140.1",0.726],["XP_024391593.1","XP_024360088.1",0.935],["XP_024391593.1","XP_024360411.1",0.862],["XP_024391593.1","XP_024375286.1",0.895],["XP_024391593.1","XP_024375304.1",0.616],["XP_024375286.1","XP_073386458.1",0.884],["XP_024375286.1","XP_024402792.1",0.966],["XP_024375286.1","XP_024359140.1",0.9],["XP_024375286.1","XP_024360088.1",0.916],["XP_024375286.1","XP_024360411.1",0.911],["XP_024375286.1","XP_024375304.1",0.889],["XP_024360088.1","XP_024359140.1",0.906],["XP_024360088.1","XP_024360411.1",0.939],["XP_024360088.1","XP_024375304.1",0.893],["XP_024360088.1","XP_024402792.1",0.878],["XP_024360088.1","XP_073386458.1",0.935],["XP_073386458.1","XP_024375304.1",0.851],["XP_073386458.1","XP_024402792.1",0.964],["XP_073386458.1","XP_024359140.1",0.869],["XP_073386458.1","XP_024360411.1",0.914],["XP_024359140.1","XP_024360411.1",0.832],["XP_024359140.1","XP_024375304.1",0.736],["XP_024359140.1","XP_024402792.1",0.967],["XP_024402792.1","XP_024375304.1",0.978],["XP_024402792.1","XP_024360411.1",0.947],["XP_024360411.1","XP_024375304.1",0.841]],"all_go_terms":{"GO:2000059":1,"GO:0050821":1,"GO:1901798":1,"GO:0032986":1,"GO:1904667":1,"GO:0071158":1,"GO:0072717":1,"GO:0006412":1,"GO:0071157":1,"GO:0030574":2,"GO:0035551":2,"GO:0034724":2,"GO:0034396":2,"GO:0042797":1,"GO:0001172":1,"GO:0006386":1,"GO:0006385":1,"GO:0006360":1,"GO:0042254":1,"GO:0006366":1,"GO:0006369":9,"GO:0070317":9,"GO:1990141":9,"GO:0000387":9,"GO:0042633":9,"GO:0000245":9,"GO:0000290":9,"GO:0008334":9,"GO:0045292":9,"GO:0009414":9,"GO:0033962":9,"GO:0008033":9,"GO:0051170":9,"GO:0009737":9,"GO:0030490":9,"GO:0022416":1,"GO:0046959":1,"GO:0034063":1,"GO:0010603":1,"GO:0090328":1,"GO:0002091":1,"GO:0042051":1,"GO:0051823":1,"GO:1905833":1,"GO:0009994":1,"GO:0097167":1,"GO:0060965":1,"GO:1904780":1,"GO:0043007":1},"recipe_readded":[]}