{"hash":"753814769100897002","title":"Redox signaling and DNA repair","description":"The top GO terms emphasize oxidative stress and redox biology (positive regulation of ROS metabolism, hydrogen peroxide metabolism) along with inflammatory regulation and DNA repair/ transcription, suggesting a cellular response to oxidative damage and genome maintenance. A couple terms point to secretory pathway roles (signal peptide processing, SRP-dependent targeting), but redox signaling and DNA damage response appear to be the dominant theme. ","confidence":"Medium","size":12,"edges":65,"triangles":210,"max_degree":11,"top_function":null,"members":[{"accession":"XP_030842518.1","go_terms":["GO:0006614"]},{"accession":"XP_030832714.1","go_terms":["GO:2000379","GO:2000609","GO:0050727","GO:0042743","GO:0015031"]},{"accession":"XP_030853508.1","go_terms":[]},{"accession":"XP_030829388.1","go_terms":["GO:0071391"]},{"accession":"XP_030828104.1","go_terms":["GO:0019044","GO:0006281","GO:0006627","GO:0006465","GO:0045892","GO:0009432","GO:0006260","GO:0006351","GO:0000746"]},{"accession":"XP_788906.1","go_terms":["GO:0045047","GO:0006465"]},{"accession":"XP_783500.1","go_terms":["GO:0006487"]},{"accession":"XP_001190261.3","go_terms":["GO:0008283","GO:1904209","GO:0071307","GO:0007155"]},{"accession":"XP_011672730.1","go_terms":[]},{"accession":"XP_800046.3","go_terms":["GO:0006613"]},{"accession":"XP_786646.3","go_terms":["GO:0006656","GO:0006686"]},{"accession":"XP_784416.1","go_terms":["GO:0006621","GO:0090004","GO:0006888","GO:0071340","GO:0006890"]}],"graph":[["XP_011672730.1","XP_001190261.3",0.698],["XP_011672730.1","XP_030828104.1",0.792],["XP_011672730.1","XP_030829388.1",0.798],["XP_011672730.1","XP_030832714.1",0.753],["XP_011672730.1","XP_030842518.1",0.67],["XP_011672730.1","XP_800046.3",0.771],["XP_011672730.1","XP_788906.1",0.65],["XP_011672730.1","XP_784416.1",0.706],["XP_011672730.1","XP_786646.3",0.594],["XP_011672730.1","XP_783500.1",0.72],["XP_011672730.1","XP_030853508.1",0.839],["XP_030842518.1","XP_030853508.1",0.562],["XP_030842518.1","XP_783500.1",0.712],["XP_030842518.1","XP_784416.1",0.677],["XP_030842518.1","XP_786646.3",0.594],["XP_030842518.1","XP_788906.1",0.559],["XP_030842518.1","XP_800046.3",0.681],["XP_030842518.1","XP_001190261.3",0.727],["XP_030842518.1","XP_030828104.1",0.787],["XP_030842518.1","XP_030829388.1",0.651],["XP_030842518.1","XP_030832714.1",0.674],["XP_030853508.1","XP_783500.1",0.706],["XP_030853508.1","XP_784416.1",0.851],["XP_030853508.1","XP_786646.3",0.798],["XP_030853508.1","XP_788906.1",0.848],["XP_030853508.1","XP_800046.3",0.694],["XP_030853508.1","XP_001190261.3",0.83],["XP_030853508.1","XP_030828104.1",0.82],["XP_030853508.1","XP_030829388.1",0.859],["XP_786646.3","XP_030832714.1",0.595],["XP_786646.3","XP_783500.1",0.72],["XP_786646.3","XP_784416.1",0.679],["XP_786646.3","XP_788906.1",0.608],["XP_786646.3","XP_800046.3",0.671],["XP_786646.3","XP_001190261.3",0.655],["XP_786646.3","XP_030828104.1",0.746],["XP_786646.3","XP_030829388.1",0.581],["XP_788906.1","XP_030832714.1",0.573],["XP_788906.1","XP_783500.1",0.751],["XP_788906.1","XP_784416.1",0.64],["XP_788906.1","XP_800046.3",0.667],["XP_788906.1","XP_001190261.3",0.707],["XP_788906.1","XP_030828104.1",0.634],["XP_788906.1","XP_030829388.1",0.584],["XP_783500.1","XP_030832714.1",0.569],["XP_783500.1","XP_800046.3",0.668],["XP_783500.1","XP_784416.1",0.66],["XP_783500.1","XP_001190261.3",0.683],["XP_783500.1","XP_030828104.1",0.793],["XP_783500.1","XP_030829388.1",0.591],["XP_784416.1","XP_030832714.1",0.662],["XP_784416.1","XP_800046.3",0.623],["XP_784416.1","XP_001190261.3",0.829],["XP_784416.1","XP_030828104.1",0.701],["XP_784416.1","XP_030829388.1",0.513],["XP_030832714.1","XP_800046.3",0.5],["XP_030832714.1","XP_001190261.3",0.674],["XP_030832714.1","XP_030828104.1",0.626],["XP_030832714.1","XP_030829388.1",0.79],["XP_030828104.1","XP_001190261.3",0.67],["XP_030828104.1","XP_030829388.1",0.807],["XP_030828104.1","XP_800046.3",0.623],["XP_800046.3","XP_001190261.3",0.666],["XP_800046.3","XP_030829388.1",0.744],["XP_001190261.3","XP_030829388.1",0.597]],"all_go_terms":{"GO:0006614":1,"GO:0015031":1,"GO:2000379":1,"GO:0050727":1,"GO:0042743":1,"GO:2000609":1,"GO:0071391":1,"GO:0006351":1,"GO:0006281":1,"GO:0006465":2,"GO:0009432":1,"GO:0006627":1,"GO:0000746":1,"GO:0045892":1,"GO:0006260":1,"GO:0019044":1,"GO:0045047":1,"GO:0006487":1,"GO:0007155":1,"GO:1904209":1,"GO:0008283":1,"GO:0071307":1,"GO:0006613":1,"GO:0006686":1,"GO:0006656":1,"GO:0071340":1,"GO:0006888":1,"GO:0090004":1,"GO:0006890":1,"GO:0006621":1},"recipe_readded":[]}