{"hash":"517202659319675593","title":"Vitamin and Coenzyme Biosynthesis with Amino Acid Metabolism","description":"The cluster centers on biosynthetic pathways for vitamins and coenzymes (menaquinone, phylloquinone, coenzyme M) and amino acid metabolism (valine, tryptophan, threonine), with additional signals of fatty acid oxidation and antibiotic biosynthesis, suggesting a broad bacterial metabolism cluster focused on small-molecule biosynthesis and turnover.","confidence":"Medium","size":27,"edges":109,"triangles":187,"max_degree":23,"top_function":null,"members":[{"accession":"XP_003725518.1","go_terms":["GO:0021535","GO:0045197","GO:0022011","GO:0022010","GO:0007294","GO:0007299","GO:0030709","GO:0051490","GO:0016325","GO:0045167","GO:0060242","GO:0051660","GO:0045186","GO:0007314","GO:2000040","GO:0008594","GO:0007377","GO:0048696","GO:0031643","GO:0090250","GO:0035845","GO:0019556","GO:0019557","GO:0006572","GO:1990359","GO:0009821","GO:0051289","GO:0017000","GO:0006559","GO:0009800","GO:0009403"]},{"accession":"XP_030842626.1","go_terms":["GO:0032148","GO:0036526","GO:0032435","GO:0036528","GO:0036529","GO:0051899","GO:0060081","GO:0051897","GO:0006351","GO:0036527","GO:0006541","GO:0098869","GO:1902958","GO:1903200","GO:0006508","GO:0036531","GO:0036530","GO:1903384","GO:0036471","GO:0002866","GO:0007338","GO:0006979","GO:0097238","GO:0090073","GO:0018323","GO:0042744","GO:2000157","GO:1903181","GO:1901671","GO:0033234","GO:2000679","GO:0033138","GO:1903122","GO:1903168","GO:0051583","GO:0050787","GO:2000277","GO:0032091","GO:1903094","GO:1903197","GO:0010273","GO:1903428","GO:0001963","GO:0045560","GO:2001268","GO:0006469","GO:1902177","GO:0061727","GO:0006914","GO:1905259","GO:1903178","GO:1903073","GO:1901984","GO:0006954","GO:0008344","GO:2000825","GO:0051444","GO:1900182","GO:0051881","GO:0033864","GO:0046826","GO:0006517","GO:0032757","GO:1903599"]},{"accession":"XP_001199448.3","go_terms":["GO:0006572","GO:1901023","GO:0006559","GO:0019380","GO:0019571"]},{"accession":"NP_001229618.1","go_terms":["GO:0070179","GO:0019499","GO:0009310","GO:0046360","GO:0043278","GO:0018871","GO:0043418","GO:0006565","GO:0006535","GO:0019295","GO:0000162","GO:0070814","GO:0042866","GO:0019346","GO:0019343","GO:0009088","GO:0070689","GO:0009097"]},{"accession":"XP_030839036.1","go_terms":["GO:0006635","GO:0042372","GO:0017000","GO:0010124","GO:0009234","GO:0006574"]},{"accession":"XP_780031.1","go_terms":["GO:0030242","GO:0006810","GO:0050826","GO:0006635","GO:0042372","GO:0017000","GO:0010124","GO:0009234","GO:0006574"]},{"accession":"XP_796963.3","go_terms":["GO:0006635","GO:0042372","GO:0017000","GO:0010124","GO:0009234","GO:0006574"]},{"accession":"XP_787534.1","go_terms":["GO:0070179","GO:0019499","GO:0009310","GO:0046360","GO:0043278","GO:0018871","GO:0043418","GO:0006565","GO:0006535","GO:0019295","GO:0000162","GO:0070814","GO:0042866","GO:0019346","GO:0019343","GO:0009088","GO:0070689","GO:0009097"]},{"accession":"XP_790539.2","go_terms":["GO:0042732","GO:0042355","GO:0019569","GO:0019521","GO:0005998","GO:0019563","GO:0019640","GO:0046835","GO:0046167","GO:0035963","GO:0019301","GO:0009372"]},{"accession":"XP_791526.2","go_terms":["GO:0006909","GO:0030240","GO:0010628","GO:0021762","GO:0034314","GO:0051654","GO:0002121","GO:0042766","GO:0043503","GO:0071963","GO:0009825","GO:0006348","GO:0000147","GO:0000001","GO:0043486","GO:0000281","GO:0016344","GO:0030476","GO:1904623","GO:0048741","GO:0032508","GO:0051017","GO:0045214","GO:0051666","GO:0030041","GO:0001895","GO:0030100","GO:0090131","GO:0051592","GO:0000011","GO:0000916","GO:0001300","GO:0043982","GO:0043983","GO:0043981","GO:0070527","GO:1903475","GO:0098974"]},{"accession":"XP_030828017.1","go_terms":["GO:0042732","GO:0042355","GO:0019569","GO:0019521","GO:0005998","GO:0019563","GO:0019640","GO:0046835","GO:0046167","GO:0035963","GO:0019301","GO:0009372"]},{"accession":"XP_782004.4","go_terms":["GO:0070179","GO:0019499","GO:0009310","GO:0046360","GO:0043278","GO:0018871","GO:0043418","GO:0006565","GO:0006535","GO:0019295","GO:0000162","GO:0070814","GO:0042866","GO:0019346","GO:0019343","GO:0009088","GO:0070689","GO:0009097"]},{"accession":"XP_030841638.1","go_terms":["GO:0032024","GO:0006739","GO:0001678","GO:0007595","GO:0061621","GO:0035795","GO:0046324","GO:0032869","GO:0044320","GO:0006013","GO:0010148","GO:0046835","GO:0032445","GO:0006110","GO:0045725","GO:0045721","GO:2000378","GO:1904925","GO:0019660","GO:1901986","GO:0090332","GO:0072656","GO:0051594","GO:0072655","GO:0002931","GO:0009747","GO:0043266","GO:0046323","GO:0070509","GO:0051156","GO:0006000","GO:0006002","GO:0009741"]},{"accession":"XP_030848644.1","go_terms":["GO:0019322","GO:0043523","GO:0021762","GO:0010041","GO:1904879","GO:0014070","GO:0032094","GO:0006740","GO:2000378","GO:0045471","GO:0009051","GO:0061052","GO:0042542","GO:0010734","GO:0006098","GO:0006695","GO:0043249","GO:0006006","GO:0006048","GO:0006043","GO:0005975","GO:0019262","GO:0006046"]},{"accession":"XP_030850914.1","go_terms":["GO:0010815","GO:0034396","GO:0034724","GO:0030574","GO:0035551"]},{"accession":"XP_794774.2","go_terms":["GO:0070584","GO:0015937","GO:1904251","GO:0016310"]},{"accession":"XP_030831200.1","go_terms":["GO:0006635","GO:0042372","GO:0017000","GO:0010124","GO:0009234","GO:0006574"]},{"accession":"XP_030831521.1","go_terms":["GO:1901121","GO:1901133"]},{"accession":"XP_030840657.1","go_terms":["GO:0007584","GO:0019619","GO:0006099","GO:0009060","GO:0006189","GO:0042594","GO:0044208","GO:0001666","GO:0042450","GO:0048873","GO:0006106","GO:0006531","GO:0014850","GO:0006108"]},{"accession":"XP_030841590.1","go_terms":["GO:0006048","GO:0097172","GO:0006051","GO:0046835"]},{"accession":"XP_030851197.1","go_terms":["GO:0010815","GO:0034396","GO:0034724","GO:0030574","GO:0035551"]},{"accession":"XP_030851555.1","go_terms":["GO:0010142","GO:0017000","GO:0070317","GO:0006695","GO:0006696","GO:0006084","GO:0009645"]},{"accession":"XP_030852585.1","go_terms":["GO:0006635","GO:0042372","GO:0017000","GO:0010124","GO:0009234","GO:0006574"]},{"accession":"XP_781065.2","go_terms":["GO:0006635","GO:0042372","GO:0017000","GO:0010124","GO:0009234","GO:0006574"]},{"accession":"XP_796433.3","go_terms":["GO:0070179","GO:0019499","GO:0009310","GO:0046360","GO:0043278","GO:0018871","GO:0043418","GO:0006565","GO:0006535","GO:0019295","GO:0000162","GO:0070814","GO:0042866","GO:0019346","GO:0019343","GO:0009088","GO:0070689","GO:0009097"]},{"accession":"NP_001229594.1","go_terms":["GO:0006635","GO:0042372","GO:0017000","GO:0010124","GO:0009234","GO:0006574"]},{"accession":"XP_003730750.3","go_terms":["GO:0006635","GO:0042372","GO:0017000","GO:0010124","GO:0009234","GO:0006574"]}],"graph":[["XP_790539.2","XP_030831521.1",0.762],["XP_790539.2","XP_030841590.1",0.807],["XP_790539.2","XP_030841638.1",0.762],["XP_790539.2","XP_030848644.1",0.576],["XP_790539.2","XP_030850914.1",0.688],["XP_790539.2","XP_030851197.1",0.664],["XP_790539.2","XP_780031.1",0.552],["XP_790539.2","XP_796963.3",0.55],["XP_790539.2","XP_791526.2",0.818],["XP_790539.2","XP_794774.2",0.738],["XP_790539.2","XP_030828017.1",0.742],["XP_787534.1","XP_782004.4",0.7],["XP_787534.1","XP_796433.3",0.69],["XP_787534.1","NP_001229618.1",0.689],["XP_796963.3","XP_030841590.1",0.797],["XP_796963.3","XP_030841638.1",0.589],["XP_796963.3","XP_030852585.1",0.524],["XP_796963.3","XP_780031.1",0.582],["XP_796963.3","NP_001229594.1",0.577],["XP_796963.3","NP_001229618.1",0.595],["XP_030839036.1","XP_030841638.1",0.75],["XP_030839036.1","XP_030842626.1",0.796],["XP_030839036.1","XP_030852585.1",0.535],["XP_030831200.1","XP_781065.2",0.622],["XP_030831200.1","XP_780031.1",0.534],["XP_030831200.1","XP_003730750.3",0.752],["XP_030831200.1","XP_030831521.1",0.544],["XP_030831200.1","XP_030842626.1",0.623],["XP_030831200.1","XP_030841590.1",0.792],["XP_030831200.1","XP_030841638.1",0.693],["NP_001229618.1","XP_003730750.3",0.557],["NP_001229618.1","XP_030841590.1",0.666],["NP_001229618.1","XP_030841638.1",0.527],["NP_001229618.1","XP_780031.1",0.505],["NP_001229618.1","XP_781065.2",0.604],["NP_001229618.1","XP_782004.4",0.803],["NP_001229618.1","XP_796433.3",0.726],["XP_003725518.1","XP_030831521.1",0.574],["XP_003725518.1","XP_030840657.1",0.687],["XP_003725518.1","XP_030841590.1",0.673],["XP_003725518.1","XP_030841638.1",0.743],["XP_003725518.1","XP_030842626.1",0.739],["XP_001199448.3","XP_781065.2",0.523],["XP_794774.2","XP_030831521.1",0.77],["XP_794774.2","XP_030841590.1",0.76],["XP_794774.2","XP_030841638.1",0.772],["XP_794774.2","XP_030851555.1",0.557],["XP_794774.2","XP_781065.2",0.516],["XP_794774.2","XP_791526.2",0.726],["XP_794774.2","XP_030828017.1",0.695],["XP_796433.3","XP_030831521.1",0.559],["XP_796433.3","XP_030841590.1",0.541],["XP_796433.3","XP_030841638.1",0.622],["XP_796433.3","XP_782004.4",0.7],["XP_030850914.1","XP_030831521.1",0.563],["XP_030850914.1","XP_030841590.1",0.669],["XP_030850914.1","XP_030841638.1",0.614],["XP_030850914.1","XP_030848644.1",0.6],["XP_030850914.1","XP_030851197.1",0.742],["XP_030850914.1","XP_030828017.1",0.666],["XP_030841638.1","XP_030840657.1",0.606],["XP_030841638.1","XP_030848644.1",0.749],["XP_030841638.1","XP_030841590.1",0.789],["XP_030841638.1","XP_030842626.1",0.901],["XP_030841638.1","XP_791526.2",0.784],["XP_030841638.1","XP_781065.2",0.679],["XP_030841638.1","XP_782004.4",0.555],["XP_030841638.1","XP_780031.1",0.744],["XP_030841638.1","XP_030852585.1",0.7],["XP_030841638.1","XP_030851197.1",0.689],["XP_030841638.1","XP_030851555.1",0.731],["XP_030841638.1","XP_003730750.3",0.716],["XP_030841638.1","XP_030828017.1",0.75],["XP_030841638.1","XP_030831521.1",0.861],["XP_030852585.1","XP_030831521.1",0.528],["XP_030852585.1","XP_030841590.1",0.666],["XP_030852585.1","XP_030842626.1",0.794],["XP_030852585.1","XP_030848644.1",0.522],["XP_030831521.1","XP_791526.2",0.741],["XP_030831521.1","XP_781065.2",0.57],["XP_030831521.1","XP_780031.1",0.532],["XP_030831521.1","XP_030851197.1",0.624],["XP_030831521.1","XP_030851555.1",0.594],["XP_030831521.1","XP_003730750.3",0.504],["XP_030831521.1","XP_030828017.1",0.723],["XP_030831521.1","XP_030848644.1",0.599],["XP_030831521.1","XP_030841590.1",0.77],["XP_030851197.1","XP_030841590.1",0.669],["XP_030851197.1","XP_030848644.1",0.606],["XP_030851197.1","XP_030828017.1",0.68],["XP_782004.4","XP_030841590.1",0.5],["XP_030840657.1","XP_030841590.1",0.771],["XP_781065.2","XP_030841590.1",0.692],["XP_781065.2","XP_030842626.1",0.665],["XP_781065.2","XP_780031.1",0.685],["XP_781065.2","XP_003730750.3",0.543],["NP_001229594.1","XP_030841590.1",0.613],["XP_030848644.1","XP_030841590.1",0.75],["XP_030848644.1","XP_003730750.3",0.674],["XP_030848644.1","XP_030828017.1",0.597],["XP_780031.1","XP_030841590.1",0.764],["XP_780031.1","XP_030842626.1",0.796],["XP_780031.1","XP_030828017.1",0.567],["XP_030841590.1","XP_791526.2",0.716],["XP_030841590.1","XP_030851555.1",0.608],["XP_030841590.1","XP_003730750.3",0.806],["XP_030841590.1","XP_030828017.1",0.771],["XP_030851555.1","XP_791526.2",0.595],["XP_791526.2","XP_030842626.1",0.695]],"all_go_terms":{"GO:0090250":1,"GO:0007314":1,"GO:0051490":1,"GO:0045167":1,"GO:0007294":1,"GO:1990359":1,"GO:0019556":1,"GO:0022010":1,"GO:0051660":1,"GO:0021535":1,"GO:0035845":1,"GO:0009403":1,"GO:0009800":1,"GO:0016325":1,"GO:0031643":1,"GO:0060242":1,"GO:0006572":2,"GO:2000040":1,"GO:0017000":10,"GO:0019557":1,"GO:0030709":1,"GO:0006559":2,"GO:0048696":1,"GO:0022011":1,"GO:0009821":1,"GO:0007299":1,"GO:0051289":1,"GO:0045197":1,"GO:0045186":1,"GO:0007377":1,"GO:0008594":1,"GO:0036529":1,"GO:0032148":1,"GO:0006351":1,"GO:0010273":1,"GO:0006541":1,"GO:1902958":1,"GO:1903599":1,"GO:1903094":1,"GO:0036527":1,"GO:0036526":1,"GO:0050787":1,"GO:2000157":1,"GO:1903197":1,"GO:0036530":1,"GO:0051444":1,"GO:0046826":1,"GO:0008344":1,"GO:2000679":1,"GO:0051897":1,"GO:0051583":1,"GO:0006517":1,"GO:1903200":1,"GO:0060081":1,"GO:1901671":1,"GO:0051881":1,"GO:0001963":1,"GO:1900182":1,"GO:1903178":1,"GO:2000825":1,"GO:0006914":1,"GO:0032091":1,"GO:0033864":1,"GO:0036471":1,"GO:2000277":1,"GO:0098869":1,"GO:1903384":1,"GO:0006979":1,"GO:1903168":1,"GO:1905259":1,"GO:1903428":1,"GO:0006508":1,"GO:1903181":1,"GO:0006469":1,"GO:2001268":1,"GO:0032435":1,"GO:0032757":1,"GO:0033138":1,"GO:0045560":1,"GO:0061727":1,"GO:1902177":1,"GO:0007338":1,"GO:0033234":1,"GO:0006954":1,"GO:1903122":1,"GO:1901984":1,"GO:0042744":1,"GO:0090073":1,"GO:0097238":1,"GO:0036528":1,"GO:0018323":1,"GO:0036531":1,"GO:0002866":1,"GO:1903073":1,"GO:0051899":1,"GO:0019380":1,"GO:0019571":1,"GO:1901023":1,"GO:0019346":4,"GO:0019295":4,"GO:0000162":4,"GO:0070689":4,"GO:0070814":4,"GO:0009097":4,"GO:0019343":4,"GO:0043418":4,"GO:0009310":4,"GO:0019499":4,"GO:0006565":4,"GO:0046360":4,"GO:0042866":4,"GO:0018871":4,"GO:0009088":4,"GO:0006535":4,"GO:0070179":4,"GO:0043278":4,"GO:0009234":8,"GO:0006635":8,"GO:0042372":8,"GO:0006574":8,"GO:0010124":8,"GO:0050826":1,"GO:0006810":1,"GO:0030242":1,"GO:0042732":2,"GO:0009372":2,"GO:0019640":2,"GO:0019521":2,"GO:0035963":2,"GO:0046835":4,"GO:0042355":2,"GO:0019563":2,"GO:0005998":2,"GO:0019569":2,"GO:0046167":2,"GO:0019301":2,"GO:0000281":1,"GO:0071963":1,"GO:0006348":1,"GO:0016344":1,"GO:0051017":1,"GO:0001895":1,"GO:0043982":1,"GO:0001300":1,"GO:0045214":1,"GO:0043486":1,"GO:0070527":1,"GO:0021762":2,"GO:0090131":1,"GO:0032508":1,"GO:0030100":1,"GO:0009825":1,"GO:0030240":1,"GO:0051592":1,"GO:0043983":1,"GO:1904623":1,"GO:0043503":1,"GO:0000011":1,"GO:0034314":1,"GO:0030041":1,"GO:1903475":1,"GO:0042766":1,"GO:0002121":1,"GO:0030476":1,"GO:0051654":1,"GO:0098974":1,"GO:0006909":1,"GO:0000916":1,"GO:0048741":1,"GO:0010628":1,"GO:0043981":1,"GO:0000001":1,"GO:0051666":1,"GO:0000147":1,"GO:0032445":1,"GO:0061621":1,"GO:0006739":1,"GO:0072655":1,"GO:0019660":1,"GO:0090332":1,"GO:0043266":1,"GO:0070509":1,"GO:0032024":1,"GO:1904925":1,"GO:0007595":1,"GO:1901986":1,"GO:0046323":1,"GO:2000378":2,"GO:0045725":1,"GO:0032869":1,"GO:0072656":1,"GO:0006002":1,"GO:0009741":1,"GO:0051156":1,"GO:0002931":1,"GO:0010148":1,"GO:0006013":1,"GO:0009747":1,"GO:0006000":1,"GO:0035795":1,"GO:0044320":1,"GO:0001678":1,"GO:0045721":1,"GO:0006110":1,"GO:0051594":1,"GO:0046324":1,"GO:0006046":1,"GO:0043523":1,"GO:0006740":1,"GO:0019322":1,"GO:0005975":1,"GO:0061052":1,"GO:0043249":1,"GO:0006043":1,"GO:0045471":1,"GO:0006098":1,"GO:1904879":1,"GO:0019262":1,"GO:0009051":1,"GO:0010734":1,"GO:0006695":2,"GO:0006006":1,"GO:0042542":1,"GO:0032094":1,"GO:0006048":2,"GO:0010041":1,"GO:0014070":1,"GO:0030574":2,"GO:0034724":2,"GO:0035551":2,"GO:0010815":2,"GO:0034396":2,"GO:0016310":1,"GO:0070584":1,"GO:1904251":1,"GO:0015937":1,"GO:1901121":1,"GO:1901133":1,"GO:0006099":1,"GO:0044208":1,"GO:0042450":1,"GO:0001666":1,"GO:0006106":1,"GO:0007584":1,"GO:0006189":1,"GO:0048873":1,"GO:0014850":1,"GO:0009060":1,"GO:0042594":1,"GO:0006531":1,"GO:0006108":1,"GO:0019619":1,"GO:0097172":1,"GO:0006051":1,"GO:0010142":1,"GO:0009645":1,"GO:0006084":1,"GO:0006696":1,"GO:0070317":1},"recipe_readded":[]}