{"hash":"405070385564525249","title":"Proteostasis and ER Stress Response","description":"Based on the top GO terms, the cluster is enriched for unfolded protein response, ER stress signaling, translation control during stress, and redox/Fe-S maturation aspects of proteome maintenance. Terms like response to unfolded protein, positive regulation of translation initiation in response to ER stress, and negative regulation of protein kinase activity point to mechanisms that maintain proteostasis under stress. Although some terms like DNA replication and tRNA import are broader, the dominant theme ties to protein quality control and stress adaptation.","confidence":"High","size":22,"edges":189,"triangles":921,"max_degree":21,"top_function":"DNA 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