{"hash":"1422690302169833284","title":"Integrin-Mediated Adhesion and Migration","description":"This cluster is dominated by GO terms centered on adhesion and movement mediated by integrins, including heterotypic cell-cell adhesion, cell-matrix adhesion, integrin signaling, extravasation, and substrate-dependent migration. Additional terms point to ECM remodeling (metallopeptidase activity) and related developmental or regenerative contexts, supporting a cohesive theme of cells attaching to and migrating through the extracellular matrix via integrin pathways. Minor elements like T cell activation reflect immune-cell interactions during migration but do not overturn the primary adhesion/migration theme.","confidence":"High","size":28,"edges":376,"triangles":3224,"max_degree":27,"top_function":"carbohydrate metabolic process","members":[{"accession":"XP_030844290.1","go_terms":["GO:0020027","GO:0042628","GO:0051561","GO:0050729","GO:0030216","GO:0072378","GO:0043163","GO:0051260","GO:0060445","GO:0048536","GO:0043123","GO:0010838","GO:0042381","GO:0048661","GO:0018153","GO:0043277","GO:0031069","GO:0060662","GO:0031424","GO:0007200","GO:0051482","GO:0001974","GO:0032471","GO:0006058","GO:0006517"]},{"accession":"XP_785426.4","go_terms":["GO:0006953","GO:0030212","GO:0006471","GO:0002291","GO:0003429","GO:0070208","GO:0034113","GO:1905050","GO:0045123","GO:0007229","GO:0007596","GO:0006929","GO:0007161","GO:0031104","GO:0006956","GO:0035987","GO:1901202","GO:0015995","GO:0048455","GO:0006511","GO:0043248","GO:0050908"]},{"accession":"XP_030833422.1","go_terms":["GO:0030070","GO:0010815","GO:0071555","GO:0000272","GO:0007155"]},{"accession":"XP_030846527.1","go_terms":["GO:2001237","GO:0051044","GO:0034446","GO:0007613","GO:1903672","GO:0038044","GO:0034113","GO:0097062","GO:2000721","GO:0030593","GO:0030511","GO:0010634","GO:0007204","GO:0090074","GO:0030198","GO:0090245","GO:1901076","GO:0010888","GO:0046718","GO:0035160","GO:0006929","GO:2000811","GO:0035313","GO:0002430","GO:0001568","GO:0035640","GO:0045919","GO:0002042","GO:0043410","GO:0035987","GO:0002291","GO:0001570","GO:0032369","GO:0045715","GO:0007229","GO:0010983","GO:0035024","GO:1990771","GO:0007044","GO:0007414","GO:0035878","GO:0006507","GO:0048333","GO:0071397","GO:0001656","GO:0043277","GO:0072006","GO:0033690","GO:0071401","GO:1903238","GO:0070371","GO:0038027","GO:0032516","GO:0050748","GO:0050901","GO:0010668","GO:0003366","GO:0097205","GO:0010745","GO:0043588","GO:0097186","GO:2000536","GO:0048745","GO:0050919","GO:0052066","GO:0007157","GO:0045123","GO:0033343","GO:0010694","GO:0043113","GO:0070527","GO:0033631","GO:0090004","GO:1903955","GO:0021551","GO:0046847","GO:0048565","GO:0035099","GO:0050873","GO:0042059","GO:0072001","GO:0001555","GO:0097192","GO:0042472","GO:0016032"]},{"accession":"XP_011681031.2","go_terms":["GO:0006953","GO:0030212","GO:0006471","GO:0002291","GO:0003429","GO:0070208","GO:0034113","GO:1905050","GO:0045123","GO:0007229","GO:0007596","GO:0006929","GO:0007161","GO:0031104","GO:0006956","GO:0035987","GO:1901202","GO:0015995","GO:0048455","GO:0006511","GO:0043248","GO:0050908"]},{"accession":"XP_030840794.1","go_terms":["GO:0006821","GO:0002291","GO:0003429","GO:0030212","GO:0070208","GO:0034113","GO:1905050","GO:0045123","GO:0007229","GO:0007596","GO:0006929","GO:0007161","GO:0031104","GO:0006956","GO:0035987","GO:1901202","GO:0015995","GO:0048455","GO:0006511","GO:0043248"]},{"accession":"XP_030845946.1","go_terms":["GO:0048675","GO:0034113","GO:0034446","GO:0007161","GO:0006909","GO:0090004","GO:0035987","GO:0030593","GO:0060298","GO:0031581","GO:1904901","GO:0055113","GO:0051216","GO:0050730","GO:0045715","GO:0046718","GO:0048565","GO:0097094","GO:0048008","GO:2000406","GO:0002042","GO:0043149","GO:0042060","GO:0060279","GO:0034142","GO:0072678","GO:0001573","GO:0097155","GO:0032369","GO:0030949","GO:0007229","GO:0010710","GO:0048813","GO:0021943","GO:0035024","GO:0045429","GO:0008542","GO:0035878","GO:1900026","GO:0002523","GO:0001708","GO:0036120","GO:0010763","GO:0014909","GO:2000811","GO:0048333","GO:1903053","GO:0060055","GO:0045214","GO:0090136","GO:0072001","GO:0051092","GO:0007568","GO:0031623","GO:0071404","GO:0001954","GO:0033690","GO:0038027","GO:1903356","GO:0050748","GO:0060971","GO:0050901","GO:0008354","GO:0003366","GO:0055007","GO:0048842","GO:0045766","GO:0010745","GO:0043588","GO:0097186","GO:0030101","GO:0045123","GO:0045124","GO:0043113","GO:0070527","GO:0033631","GO:0006930","GO:0021551","GO:0007377","GO:0035160","GO:0035001","GO:0007431","GO:0003344","GO:0048803","GO:0061097","GO:0035099","GO:0048146","GO:0007508"]},{"accession":"XP_030856412.1","go_terms":["GO:0021784","GO:0021785","GO:0035563","GO:0036083","GO:0043931","GO:0060174","GO:0048485","GO:0061399","GO:0050923","GO:0007169","GO:0001886","GO:0043087","GO:0061419","GO:0021960","GO:0033689","GO:0048843","GO:1902287","GO:0021644","GO:0021793","GO:1900220","GO:0021935","GO:1990138","GO:2000535","GO:0048215","GO:0021637","GO:2001028","GO:0021615","GO:0021612","GO:0050918","GO:0060666","GO:0006893","GO:0005975","GO:0050772","GO:0003403","GO:0007275","GO:2000305","GO:0021860","GO:1901299","GO:0060976","GO:0014910","GO:0021766","GO:0070593","GO:0043542","GO:0001756","GO:0001569","GO:0097374","GO:2001222","GO:0003151","GO:0021915","GO:0045138","GO:0060037","GO:0034260","GO:0014068","GO:0048675","GO:0007405","GO:0051642","GO:0003279","GO:0007162","GO:0071678","GO:0090597","GO:0035904"]},{"accession":"XP_030838903.1","go_terms":["GO:0021784","GO:0021785","GO:0035563","GO:0036083","GO:0043931","GO:0060174","GO:0048485","GO:0061399","GO:0050923","GO:0007169","GO:0001886","GO:0043087","GO:0061419","GO:0021960","GO:0033689","GO:0048843","GO:1902287","GO:0021644","GO:0021793","GO:1900220","GO:0021935","GO:1990138","GO:2000535","GO:0048215","GO:0021637",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