{"hash":"1310377361768889761","title":"Lipoxygenase-driven inflammatory lipid biosynthesis","description":"This cluster is dominated by GO terms for leukotriene biosynthesis and the lipoxygenase pathway, with supporting terms related to lipid hydroperoxide response and cellular oxidant detoxification, all pointing to the production and handling of inflammatory lipid mediators. Chronic inflammatory response also appears, reinforcing this theme. Calcium signaling and protein homotrimerization may be ancillary, but the core interpretation is lipoxygenase-dependent lipid mediator synthesis driving inflammation.","confidence":"High","size":18,"edges":102,"triangles":336,"max_degree":16,"top_function":null,"members":[{"accession":"XP_791177.3","go_terms":["GO:1901482","GO:1901481","GO:0006867","GO:0090452","GO:0090513","GO:0090515","GO:0090514","GO:0090517","GO:0090516","GO:0090518","GO:1990818","GO:0051365","GO:0048829","GO:0089707","GO:0061402","GO:0089708","GO:2000487","GO:0015824","GO:0015808"]},{"accession":"XP_011678547.2","go_terms":["GO:0050976","GO:0030322","GO:0071805","GO:0098914","GO:0030007","GO:0060075"]},{"accession":"XP_030832841.1","go_terms":["GO:0007635","GO:0017085","GO:0016544","GO:0031000","GO:0050913","GO:1901354","GO:0046957","GO:0019233","GO:0010037","GO:0003031","GO:0009731","GO:0007637","GO:0034289","GO:0051594","GO:0050916","GO:0010353"]},{"accession":"XP_030831756.1","go_terms":["GO:0034975"]},{"accession":"XP_030847359.1","go_terms":[]},{"accession":"XP_030845630.1","go_terms":["GO:0050965","GO:0050966","GO:0050968","GO:0060025","GO:0035002","GO:0055078","GO:0010447","GO:1905792","GO:0035725","GO:0035179","GO:0046929","GO:0050915","GO:0050914","GO:0003026","GO:0035199","GO:0050891","GO:0071467","GO:1905789"]},{"accession":"XP_784920.3","go_terms":["GO:0033327","GO:0032496","GO:0043085","GO:0098869","GO:0014070","GO:0019372","GO:0019370","GO:0008285","GO:0032526","GO:0070207","GO:0034097","GO:2001300","GO:0070268","GO:0071277","GO:0001516","GO:0002526","GO:0002540","GO:0002544","GO:0071449"]},{"accession":"XP_780791.2","go_terms":["GO:0030728","GO:0070509","GO:0061180","GO:0002115"]},{"accession":"XP_003729096.1","go_terms":["GO:0033327","GO:0032496","GO:0043085","GO:0098869","GO:0014070","GO:0019372","GO:0019370","GO:0008285","GO:0032526","GO:0070207","GO:0034097","GO:2001300","GO:0070268","GO:0071277","GO:0001516","GO:0002526","GO:0002540","GO:0002544","GO:0071449"]},{"accession":"XP_001180933.2","go_terms":["GO:0033327","GO:0032496","GO:0043085","GO:0098869","GO:0014070","GO:0019372","GO:0019370","GO:0008285","GO:0032526","GO:0070207","GO:0034097","GO:2001300","GO:0070268","GO:0071277","GO:0001516","GO:0002526","GO:0002540","GO:0002544","GO:0071449"]},{"accession":"XP_793842.2","go_terms":["GO:0033327","GO:0032496","GO:0043085","GO:0098869","GO:0014070","GO:0019372","GO:0019370","GO:0008285","GO:0032526","GO:0070207","GO:0034097","GO:2001300","GO:0070268","GO:0071277","GO:0001516","GO:0002526","GO:0002540","GO:0002544","GO:0071449"]},{"accession":"XP_784976.3","go_terms":["GO:0033327","GO:0032496","GO:0043085","GO:0098869","GO:0014070","GO:0019372","GO:0019370","GO:0008285","GO:0032526","GO:0070207","GO:0034097","GO:2001300","GO:0070268","GO:0071277","GO:0001516","GO:0002526","GO:0002540","GO:0002544","GO:0071449"]},{"accession":"XP_001178007.1","go_terms":["GO:0033327","GO:0032496","GO:0043085","GO:0098869","GO:0014070","GO:0019372","GO:0019370","GO:0008285","GO:0032526","GO:0070207","GO:0034097","GO:2001300","GO:0070268","GO:0071277","GO:0001516","GO:0002526","GO:0002540","GO:0002544","GO:0071449"]},{"accession":"XP_011673506.2","go_terms":[]},{"accession":"XP_030854048.1","go_terms":["GO:0033327","GO:0032496","GO:0043085","GO:0098869","GO:0014070","GO:0019372","GO:0019370","GO:0008285","GO:0032526","GO:0070207","GO:0034097","GO:2001300","GO:0070268","GO:0071277","GO:0001516","GO:0002526","GO:0002540","GO:0002544","GO:0071449"]},{"accession":"XP_784337.2","go_terms":["GO:0033327","GO:0032496","GO:0043085","GO:0098869","GO:0014070","GO:0019372","GO:0019370","GO:0008285","GO:0032526","GO:0070207","GO:0034097","GO:2001300","GO:0070268","GO:0071277","GO:0001516","GO:0002526","GO:0002540","GO:0002544","GO:0071449"]},{"accession":"XP_785095.3","go_terms":["GO:0033327","GO:0032496","GO:0043085","GO:0098869","GO:0014070","GO:0019372","GO:0019370","GO:0008285","GO:0032526","GO:0070207","GO:0034097","GO:2001300","GO:0070268","GO:0071277","GO:0001516","GO:0002526","GO:0002540","GO:0002544","GO:0071449"]},{"accession":"XP_003729526.1","go_terms":[]}],"graph":[["XP_030831756.1","XP_784920.3",0.588],["XP_030831756.1","XP_784976.3",0.518],["XP_030831756.1","XP_785095.3",0.563],["XP_030831756.1","XP_011673506.2",0.538],["XP_030831756.1","XP_030832841.1",0.546],["XP_030831756.1","XP_030847359.1",0.559],["XP_784337.2","XP_030832841.1",0.523],["XP_784337.2","XP_030847359.1",0.567],["XP_784337.2","XP_030854048.1",0.621],["XP_784337.2","XP_780791.2",0.536],["XP_784337.2","XP_784920.3",0.65],["XP_784337.2","XP_784976.3",0.608],["XP_784337.2","XP_785095.3",0.59],["XP_784337.2","XP_793842.2",0.528],["XP_784337.2","XP_001178007.1",0.624],["XP_784337.2","XP_001180933.2",0.585],["XP_784337.2","XP_003729096.1",0.649],["XP_784337.2","XP_011673506.2",0.604],["XP_784337.2","XP_011678547.2",0.522],["XP_011678547.2","XP_001178007.1",0.559],["XP_011678547.2","XP_001180933.2",0.51],["XP_011678547.2","XP_030832841.1",0.509],["XP_011678547.2","XP_030845630.1",0.567],["XP_011678547.2","XP_030847359.1",0.536],["XP_011678547.2","XP_785095.3",0.523],["XP_011678547.2","XP_793842.2",0.533],["XP_793842.2","XP_03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