{"hash":"1293169051078299565","title":"Proteostasis and intracellular trafficking","description":"This cluster centers on protein homeostasis and cargo handling within the cell, as indicated by repeated signals for protein folding and chaperone-assisted assembly, sumoylation, and ubiquitin-proteasome\u2013mediated quality control. Additional terms point to vesicle and organelle trafficking (lysosome localization and pigment/granule organization) and cytoskeletal involvement (tubulin complex assembly, mitotic chromosome alignment), suggesting a cohesive theme of folding, modification, degradation, and transport of proteins and organelles. Overall, the proteins appear to function together in maintaining proteostasis while coordinating intracellular trafficking.","confidence":"Medium","size":25,"edges":278,"triangles":1864,"max_degree":24,"top_function":"protein 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