{"hash":"1198307057942213058","title":"mRNA splicing and translation initiation regulation","description":"The Top Terms cluster around mRNA processing and translational control: spliceosome-mediated splicing, splice-site recognition, translation initiation and preinitiation complex formation, translation reinitiation, and mRNA modification/stability. This suggests the proteins function primarily in post-transcriptional gene expression regulation, coordinating splicing with initiation of translation. Given the co-occurrence of splicing- and initiation-related terms, the label captures the cluster's central theme.","confidence":"High","size":12,"edges":63,"triangles":193,"max_degree":11,"top_function":"regulatory ncRNA-mediated gene silencing","members":[{"accession":"XP_030849178.1","go_terms":["GO:0000245","GO:0000398"]},{"accession":"XP_030836621.1","go_terms":[]},{"accession":"XP_786252.1","go_terms":["GO:0008033","GO:0033962","GO:0008334","GO:0070317","GO:0051170","GO:1990141","GO:0009414","GO:0042633","GO:0000245","GO:0000387","GO:0000290","GO:0009737","GO:0030490","GO:0006369","GO:0045292"]},{"accession":"XP_003729862.2","go_terms":["GO:1905663","GO:1902625","GO:0048025","GO:0048026","GO:0075522","GO:0075525","GO:0000380","GO:0016556","GO:0001825","GO:1900363","GO:0002188","GO:0000381","GO:1903586","GO:0006406","GO:0006446","GO:0060211","GO:0031047","GO:0048255","GO:0035278","GO:0001731","GO:0010610","GO:0045292","GO:1901407","GO:0097010","GO:0006376","GO:0034462","GO:0006378"]},{"accession":"XP_011668379.1","go_terms":["GO:1905663","GO:1902625","GO:0048025","GO:0048026","GO:0075522","GO:0075525","GO:0000380","GO:0016556","GO:0001825","GO:1900363","GO:0002188","GO:0000381","GO:1903586","GO:0006406","GO:0006446","GO:0060211","GO:0031047","GO:0048255","GO:0035278","GO:0001731","GO:0010610","GO:0045292","GO:1901407","GO:0097010","GO:0006376","GO:0034462","GO:0006378","GO:0071230","GO:0046011","GO:1900365","GO:0071456","GO:1900248","GO:0008069","GO:0061158","GO:0060213","GO:0007310","GO:0032869","GO:0002931","GO:0045451"]},{"accession":"XP_011673791.2","go_terms":["GO:1905663","GO:1902625","GO:0048025","GO:0048026","GO:0075522","GO:0075525","GO:0000380","GO:0016556","GO:0001825","GO:1900363","GO:0002188","GO:0000381","GO:1903586","GO:0006406","GO:0006446","GO:0060211","GO:0031047","GO:0048255","GO:0035278","GO:0001731","GO:0010610","GO:0045292","GO:1901407","GO:0097010","GO:0006376","GO:0034462","GO:0006378"]},{"accession":"XP_030829712.1","go_terms":["GO:0030238","GO:0050810","GO:0030575","GO:0033327","GO:0000398","GO:0044830","GO:0048024","GO:0022013","GO:0070935","GO:0097222","GO:0006402","GO:0098908","GO:2000627","GO:0016120","GO:0033129","GO:0043577","GO:1902416","GO:0090503","GO:0010610","GO:1901254","GO:0010323","GO:2000637","GO:0010738","GO:0045716","GO:0071031","GO:0010587","GO:0019076","GO:0075713","GO:0019068","GO:0039702","GO:0030260","GO:0039651","GO:0015074"]},{"accession":"XP_030829714.1","go_terms":["GO:0030238","GO:0050810","GO:0030575","GO:0033327","GO:0000398","GO:0044830","GO:0048024","GO:0022013","GO:0070935","GO:0097222","GO:0006402","GO:0098908","GO:2000627","GO:0016120","GO:0033129","GO:0043577","GO:1902416","GO:0090503","GO:0010610","GO:1901254","GO:0010323","GO:2000637","GO:0010738","GO:0045716","GO:0071031","GO:0010587","GO:0019076","GO:0075713","GO:0019068","GO:0039702","GO:0030260","GO:0039651","GO:0015074"]},{"accession":"XP_030839848.1","go_terms":[]},{"accession":"XP_030843904.1","go_terms":["GO:0000290","GO:0033962","GO:0010607","GO:0045947"]},{"accession":"XP_030851361.1","go_terms":["GO:1905663","GO:1902625","GO:0048025","GO:0048026","GO:0075522","GO:0075525","GO:0000380","GO:0016556","GO:0001825","GO:1900363","GO:0002188","GO:0000381","GO:1903586","GO:0006406","GO:0006446","GO:0060211","GO:0031047","GO:0048255","GO:0035278","GO:0001731","GO:0010610","GO:0045292","GO:1901407","GO:0097010","GO:0006376","GO:0034462","GO:0006378","GO:0072423","GO:0030847","GO:0030846","GO:0098789","GO:0042868"]},{"accession":"XP_001199313.3","go_terms":["GO:1902213","GO:0050775","GO:0009955","GO:0097150","GO:0048366","GO:1900170","GO:0016358","GO:0048013"]}],"graph":[["XP_030829712.1","XP_030851361.1",0.626],["XP_030829712.1","XP_786252.1",0.61],["XP_030829712.1","XP_001199313.3",0.581],["XP_030829712.1","XP_003729862.2",0.689],["XP_030829712.1","XP_011668379.1",0.681],["XP_030829712.1","XP_011673791.2",0.63],["XP_030829712.1","XP_030829714.1",0.66],["XP_030829712.1","XP_030836621.1",0.615],["XP_030829712.1","XP_030839848.1",0.606],["XP_030829712.1","XP_030843904.1",0.64],["XP_030829712.1","XP_030849178.1",0.68],["XP_030829714.1","XP_030851361.1",0.626],["XP_030829714.1","XP_786252.1",0.629],["XP_030829714.1","XP_001199313.3",0.595],["XP_030829714.1","XP_003729862.2",0.701],["XP_030829714.1","XP_011668379.1",0.696],["XP_030829714.1","XP_011673791.2",0.643],["XP_030829714.1","XP_030836621.1",0.624],["XP_030829714.1","XP_030839848.1",0.605],["XP_030829714.1","XP_030843904.1",0.637],["XP_030829714.1","XP_030849178.1",0.702],["XP_003729862.2","XP_001199313.3",0.618],["XP_003729862.2","XP_011673791.2",0.682],["XP_003729862.2","XP_011668379.1",0.722],["XP_003729862.2","XP_030839848.1",0.513],["XP_003729862.2","XP_030836621.1",0.661],["XP_003729862.2","XP_030849178.1",0.672],["XP_003729862.2","XP_030843904.1",0.605],["XP_003729862.2","XP_786252.1",0.667],["XP_003729862.2","XP_030851361.1",0.651],["XP_030839848.1","XP_030843904.1",0.511],["XP_030839848.1","XP_030849178.1",0.684],["XP_030839848.1","XP_786252.1",0.546],["XP_030839848.1","XP_001199313.3",0.561],["XP_030839848.1","XP_030836621.1",0.525],["XP_030849178.1","XP_030836621.1",0.677],["XP_030849178.1","XP_030843904.1",0.698],["XP_030849178.1","XP_786252.1",0.656],["XP_030849178.1","XP_030851361.1",0.645],["XP_030849178.1","XP_001199313.3",0.608],["XP_030849178.1","XP_011668379.1",0.616],["XP_030849178.1","XP_011673791.2",0.667],["XP_011673791.2","XP_001199313.3",0.544],["XP_011673791.2","XP_011668379.1",0.708],["XP_011673791.2","XP_030836621.1",0.65],["XP_011673791.2","XP_030843904.1",0.534],["XP_011673791.2","XP_786252.1",0.616],["XP_011673791.2","XP_030851361.1",0.676],["XP_001199313.3","XP_011668379.1",0.612],["XP_001199313.3","XP_030836621.1",0.561],["XP_001199313.3","XP_030843904.1",0.625],["XP_001199313.3","XP_786252.1",0.562],["XP_001199313.3","XP_030851361.1",0.695],["XP_786252.1","XP_030836621.1",0.55],["XP_786252.1","XP_030843904.1",0.646],["XP_786252.1","XP_030851361.1",0.602],["XP_786252.1","XP_011668379.1",0.681],["XP_030843904.1","XP_030836621.1",0.615],["XP_030843904.1","XP_030851361.1",0.578],["XP_030843904.1","XP_011668379.1",0.543],["XP_030836621.1","XP_030851361.1",0.616],["XP_030836621.1","XP_011668379.1",0.674],["XP_011668379.1","XP_030851361.1",0.671]],"all_go_terms":{"GO:0000398":3,"GO:0000245":2,"GO:1990141":1,"GO:0042633":1,"GO:0009737":1,"GO:0008033":1,"GO:0051170":1,"GO:0006369":1,"GO:0000290":2,"GO:0009414":1,"GO:0070317":1,"GO:0033962":2,"GO:0000387":1,"GO:0045292":5,"GO:0030490":1,"GO:0008334":1,"GO:0006446":4,"GO:0016556":4,"GO:0097010":4,"GO:0006376":4,"GO:0002188":4,"GO:0031047":4,"GO:0001731":4,"GO:1900363":4,"GO:0035278":4,"GO:0060211":4,"GO:0000381":4,"GO:1901407":4,"GO:0000380":4,"GO:0075525":4,"GO:0006378":4,"GO:0006406":4,"GO:0048026":4,"GO:0034462":4,"GO:0048255":4,"GO:0048025":4,"GO:1905663":4,"GO:1902625":4,"GO:0075522":4,"GO:0010610":6,"GO:1903586":4,"GO:0001825":4,"GO:0045451":1,"GO:0046011":1,"GO:0008069":1,"GO:0007310":1,"GO:0071456":1,"GO:0032869":1,"GO:0002931":1,"GO:1900248":1,"GO:0071230":1,"GO:0061158":1,"GO:0060213":1,"GO:1900365":1,"GO:0044830":2,"GO:1901254":2,"GO:0043577":2,"GO:0010587":2,"GO:0048024":2,"GO:0019068":2,"GO:0030575":2,"GO:0045716":2,"GO:2000627":2,"GO:0010323":2,"GO:0097222":2,"GO:0039702":2,"GO:0098908":2,"GO:0030238":2,"GO:0070935":2,"GO:0019076":2,"GO:0016120":2,"GO:0015074":2,"GO:0030260":2,"GO:0033327":2,"GO:0022013":2,"GO:0033129":2,"GO:0039651":2,"GO:0006402":2,"GO:0090503":2,"GO:0071031":2,"GO:0010738":2,"GO:0050810":2,"GO:0075713":2,"GO:1902416":2,"GO:2000637":2,"GO:0045947":1,"GO:0010607":1,"GO:0030847":1,"GO:0098789":1,"GO:0030846":1,"GO:0042868":1,"GO:0072423":1,"GO:0009955":1,"GO:0048366":1,"GO:0050775":1,"GO:1902213":1,"GO:0048013":1,"GO:1900170":1,"GO:0097150":1,"GO:0016358":1},"recipe_readded":[]}