{"hash":"1978419495849586171","title":"Alzheimer's-related protein processing and trafficking","description":"The GO terms show a theme of neuronal protein handling across secretory and endolysosomal pathways, including negative regulation of amyloid-beta formation, negative regulation of neurofibrillary tangle assembly, and endosome-to-lysosome transport, plus ER exit regulation. This combination points to a cohesive cluster centered on neuronal protein processing and trafficking with relevance to Alzheimer's disease pathology.","confidence":"High","size":8,"edges":0,"triangles":0,"max_degree":0,"top_function":null,"members":[{"accession":"XP_005099615.1","go_terms":[]},{"accession":"XP_012946053.1","go_terms":[]},{"accession":"XP_035826126.1","go_terms":[]},{"accession":"XP_035828900.1","go_terms":[]},{"accession":"XP_005089476.1","go_terms":[]},{"accession":"XP_012945617.1","go_terms":[]},{"accession":"XP_035829007.1","go_terms":["GO:0014910","GO:0008333","GO:0051005","GO:0046323","GO:2001137","GO:1900452","GO:1902997","GO:0070863","GO:0008625","GO:1902771","GO:0045599","GO:1902955","GO:0032460","GO:1902953","GO:0014902","GO:0006622","GO:1902430","GO:0048011","GO:0006895","GO:0048227","GO:1902960","GO:1902963","GO:1902948","GO:1902966"]},{"accession":"XP_005112966.2","go_terms":[]}],"graph":[],"all_go_terms":{"GO:1902430":1,"GO:0051005":1,"GO:0070863":1,"GO:0032460":1,"GO:1900452":1,"GO:1902997":1,"GO:0046323":1,"GO:1902960":1,"GO:0008333":1,"GO:0045599":1,"GO:1902948":1,"GO:0048227":1,"GO:1902966":1,"GO:1902771":1,"GO:1902955":1,"GO:2001137":1,"GO:0048011":1,"GO:0014902":1,"GO:0008625":1,"GO:0014910":1,"GO:0006622":1,"GO:0006895":1,"GO:1902953":1,"GO:1902963":1},"recipe_readded":["XP_012939232.1","XP_005089663.1","XP_012936589.1","XP_012942463.1","XP_005097498.1","XP_005097637.1","XP_012942474.1","XP_005096108.1","XP_005100154.1","XP_012940687.1","XP_005103143.1","XP_005092223.1","XP_005112509.1","XP_012940686.1","XP_012942603.1","XP_005111430.1","XP_005113139.1","XP_005097887.1","XP_012939746.1","XP_035827436.1"]}