{"hash":"1705334372939435008","title":"Ubiquitin-mediated transcriptional and cell fate regulation","description":"Based on GO terms, this cluster centers on negative regulation of transcription by RNA Pol II, ubiquitination (polyubiquitination), and modulation of apoptotic/necroptotic pathways, with additional signals related to TLR signaling and cell cycle control. This suggests a cohesive theme of ubiquitin-dependent regulation of transcription and cell fate decisions, rather than a single linear pathway. Some meiosis-related terms appear but do not define the core function.","confidence":"Medium","size":13,"edges":0,"triangles":0,"max_degree":0,"top_function":null,"members":[{"accession":"NP_175252.1","go_terms":[]},{"accession":"NP_177535.2","go_terms":["GO:0060544","GO:0000122","GO:0034121","GO:0043066","GO:0000209","GO:0071157"]},{"accession":"NP_187923.1","go_terms":["GO:0042138","GO:0042139","GO:0051026","GO:0031619","GO:0007141","GO:0009553","GO:0001541","GO:0009555","GO:1990918","GO:0000706","GO:0006265","GO:0006268","GO:0048316","GO:0042140","GO:0045141","GO:0007131","GO:0007130","GO:0048477","GO:0000737"]},{"accession":"NP_189548.1","go_terms":["GO:0010497","GO:0031640","GO:0042742","GO:0010951"]},{"accession":"NP_193338.2","go_terms":[]},{"accession":"NP_197834.1","go_terms":[]},{"accession":"NP_199082.1","go_terms":["GO:0010274"]},{"accession":"NP_850561.1","go_terms":[]},{"accession":"NP_001117243.1","go_terms":["GO:0000162"]},{"accession":"NP_001318350.1","go_terms":[]},{"accession":"NP_001322804.1","go_terms":["GO:0060544","GO:0000122","GO:0034121","GO:0043066","GO:0000209","GO:0071157"]},{"accession":"NP_001324660.1","go_terms":[]},{"accession":"NP_001327126.1","go_terms":[]}],"graph":[],"all_go_terms":{"GO:0000122":2,"GO:0060544":2,"GO:0000209":2,"GO:0043066":2,"GO:0034121":2,"GO:0071157":2,"GO:0006265":1,"GO:0048316":1,"GO:0007131":1,"GO:0042139":1,"GO:0007141":1,"GO:0042140":1,"GO:0048477":1,"GO:0042138":1,"GO:0000737":1,"GO:0000706":1,"GO:0006268":1,"GO:0007130":1,"GO:0001541":1,"GO:0045141":1,"GO:0009555":1,"GO:1990918":1,"GO:0051026":1,"GO:0009553":1,"GO:0031619":1,"GO:0042742":1,"GO:0010951":1,"GO:0010497":1,"GO:0031640":1,"GO:0010274":1,"GO:0000162":1},"recipe_readded":["NP_051095.1","NP_001325273.1","NP_177984.1","NP_180936.1"]}