{"hash":"813676084075504263","title":"ER-Golgi vesicle trafficking","description":"This cluster is enriched for vesicle fusion and trafficking terms between the ER and Golgi (GO:0048279, GO:0016320, GO:0048280), indicating involvement in the intracellular secretory pathway. Additional terms on lipoprotein metabolism and lipid transport align with secretory/endocrine roles that rely on vesicle trafficking, while some differentiation and receptor internalization terms suggest broader trafficking involvement across cell types. Overall, the dominant theme is ER-Golgi vesicle trafficking with supporting secretory and lipid-handling functions.","confidence":"Medium","size":8,"edges":10,"triangles":0,"max_degree":5,"top_function":null,"members":[{"accession":"NP_077181.1","go_terms":["GO:0035987"]},{"accession":"NP_081435.1","go_terms":[]},{"accession":"NP_742161.4","go_terms":["GO:0048280","GO:0048279","GO:0016320"]},{"accession":"NP_776104.1","go_terms":["GO:0042157","GO:0042118","GO:0006869"]},{"accession":"XP_030105541.1","go_terms":["GO:0048280","GO:0048279","GO:0016320"]},{"accession":"NP_001020417.1","go_terms":[]},{"accession":"NP_001399550.1","go_terms":["GO:1990926","GO:0031629","GO:0032024","GO:0030252","GO:0071805","GO:0007616","GO:0002553","GO:0016082","GO:0031915","GO:0048791","GO:0051963","GO:0048172","GO:0030431","GO:0007409","GO:0098967","GO:0099590","GO:0035493"]},{"accession":"NP_598896.3","go_terms":["GO:0010312","GO:0070574","GO:0060173","GO:0006882","GO:0006831","GO:0006830","GO:0044749","GO:0034224","GO:1903615"]}],"graph":[["NP_001399550.1","NP_598896.3",0.738],["NP_001399550.1","NP_776104.1",0.637],["NP_001399550.1","NP_001020417.1",0.689],["NP_081435.1","NP_776104.1",0.553],["NP_081435.1","NP_001020417.1",0.618],["NP_776104.1","NP_077181.1",0.934],["NP_776104.1","NP_742161.4",0.595],["NP_776104.1","XP_030105541.1",0.698],["XP_030105541.1","NP_001020417.1",0.542],["NP_077181.1","NP_001020417.1",0.929]],"all_go_terms":{"GO:0035987":1,"GO:0048279":2,"GO:0016320":2,"GO:0048280":2,"GO:0042157":1,"GO:0042118":1,"GO:0006869":1,"GO:0099590":1,"GO:0030431":1,"GO:0030252":1,"GO:0035493":1,"GO:0007409":1,"GO:0032024":1,"GO:0031629":1,"GO:0007616":1,"GO:0048172":1,"GO:0098967":1,"GO:0016082":1,"GO:1990926":1,"GO:0002553":1,"GO:0071805":1,"GO:0051963":1,"GO:0031915":1,"GO:0048791":1,"GO:0006882":1,"GO:0006830":1,"GO:0034224":1,"GO:0044749":1,"GO:1903615":1,"GO:0006831":1,"GO:0060173":1,"GO:0010312":1,"GO:0070574":1},"recipe_readded":[]}