{"hash":"496272228924264607","title":"Ubiquitination and proteostasis regulation","description":"The top terms cluster around protein ubiquitination (ubiquitin-dependent ERAD, autoubiquitination, K63-linked ubiquitination) and related protein quality control processes, with supporting hints from phosphorylation and chaperone complex assembly. Although a few terms touch on DNA replication termination or photomorphogenesis, the strongest theme is ubiquitin signaling governing protein degradation and quality control.","confidence":"Medium","size":7,"edges":9,"triangles":0,"max_degree":5,"top_function":null,"members":[{"accession":"NP_079809.1","go_terms":["GO:0051001","GO:0009640","GO:0050999","GO:1902979","GO:0040022","GO:0071171","GO:0008626","GO:0030579","GO:0090035","GO:0010200","GO:0071361","GO:0090359","GO:0051865","GO:0030433","GO:0031943","GO:0070534"]},{"accession":"XP_030111343.1","go_terms":[]},{"accession":"XP_006515114.1","go_terms":[]},{"accession":"XP_006533212.1","go_terms":["GO:0009157","GO:0016310","GO:0046104","GO:0071897"]},{"accession":"NP_001272357.1","go_terms":["GO:0035750","GO:1903753","GO:0070830","GO:0045197","GO:0014051","GO:0046328","GO:0071847","GO:0090557","GO:0035641","GO:0046711","GO:0070978","GO:0090162","GO:0035418","GO:0097120","GO:0006015","GO:0016310","GO:0071625","GO:2001205","GO:1903760","GO:1903286","GO:0046037","GO:1903764","GO:0051660","GO:0045186","GO:0001771","GO:2000821","GO:0072578","GO:0070588","GO:0016188","GO:0098912","GO:0019634","GO:0048541","GO:0071896"]},{"accession":"NP_035404.4","go_terms":["GO:0007021","GO:1990115","GO:1990114","GO:0006457","GO:0031137","GO:1990113","GO:0032968"]},{"accession":"NP_001277268.1","go_terms":["GO:0048745","GO:0006616","GO:0071243","GO:0060324","GO:0003016","GO:0071218","GO:0010761"]}],"graph":[["NP_035404.4","NP_079809.1",0.671],["NP_035404.4","XP_006533212.1",0.938],["NP_035404.4","XP_006515114.1",0.545],["NP_035404.4","NP_001272357.1",0.753],["NP_035404.4","NP_001277268.1",0.806],["XP_006515114.1","XP_030111343.1",0.956],["NP_001277268.1","XP_030111343.1",0.813],["NP_001272357.1","XP_030111343.1",0.846],["XP_006533212.1","XP_030111343.1",0.818]],"all_go_terms":{"GO:0030433":1,"GO:0051865":1,"GO:0071171":1,"GO:0090035":1,"GO:0009640":1,"GO:1902979":1,"GO:0070534":1,"GO:0008626":1,"GO:0051001":1,"GO:0030579":1,"GO:0040022":1,"GO:0071361":1,"GO:0090359":1,"GO:0050999":1,"GO:0031943":1,"GO:0010200":1,"GO:0071897":1,"GO:0016310":2,"GO:0046104":1,"GO:0009157":1,"GO:0046711":1,"GO:0045197":1,"GO:0006015":1,"GO:0097120":1,"GO:0035750":1,"GO:0046328":1,"GO:0035418":1,"GO:0019634":1,"GO:0071896":1,"GO:0001771":1,"GO:0070588":1,"GO:0045186":1,"GO:0035641":1,"GO:0014051":1,"GO:0071847":1,"GO:0070978":1,"GO:1903764":1,"GO:0090162":1,"GO:1903753":1,"GO:0016188":1,"GO:1903760":1,"GO:0051660":1,"GO:0090557":1,"GO:0071625":1,"GO:0048541":1,"GO:0046037":1,"GO:0072578":1,"GO:0070830":1,"GO:2001205":1,"GO:0098912":1,"GO:1903286":1,"GO:2000821":1,"GO:0006457":1,"GO:0031137":1,"GO:1990113":1,"GO:0032968":1,"GO:0007021":1,"GO:1990114":1,"GO:1990115":1,"GO:0060324":1,"GO:0071243":1,"GO:0003016":1,"GO:0071218":1,"GO:0048745":1,"GO:0006616":1,"GO:0010761":1},"recipe_readded":[]}