{"hash":"1728786833764277974","title":"ER Membrane Targeting and Cotranslational Translocation","description":"The top GO terms cluster around translation initiation and preinitiation complex formation, plus several terms for targeting proteins to membranes, especially the ER membrane, via SRP-dependent cotranslational pathways and Sec-dependent transport. This points to a cohesive theme of proteins involved in translating and efficiently delivering nascent polypeptides to the endoplasmic reticulum membrane for proper processing, with some developmental terms possibly reflecting tissue-specific expression. ","confidence":"Medium","size":9,"edges":23,"triangles":29,"max_degree":8,"top_function":null,"members":[{"accession":"NP_001404618.1","go_terms":["GO:0009048","GO:0006417","GO:0002188","GO:0032790","GO:1990145","GO:0002192","GO:0001731"]},{"accession":"NP_033110.1","go_terms":["GO:0006412"]},{"accession":"NP_067280.1","go_terms":["GO:0070843","GO:0006605","GO:0039019","GO:0030970","GO:0043952","GO:0031204","GO:0006616","GO:0007275","GO:0006620","GO:0030433"]},{"accession":"NP_079869.1","go_terms":["GO:0042254","GO:0001172","GO:0006360","GO:0006366","GO:0006386","GO:0006385","GO:0042797"]},{"accession":"NP_080527.2","go_terms":["GO:0000290","GO:0033962","GO:0010607","GO:0045947"]},{"accession":"NP_598694.3","go_terms":["GO:0018279"]},{"accession":"XP_006500149.1","go_terms":["GO:0000290","GO:0033962","GO:0010607","GO:0045947"]},{"accession":"NP_001343340.1","go_terms":["GO:0070843","GO:0006605","GO:0039019","GO:0030970","GO:0043952","GO:0031204","GO:0006616","GO:0007275","GO:0006620","GO:0030433"]},{"accession":"NP_032414.1","go_terms":["GO:0032436","GO:0001701","GO:0048142","GO:0043248","GO:0007127","GO:0075525","GO:0000122","GO:0008283","GO:0002188","GO:0035914","GO:1902416","GO:0071033","GO:0006283","GO:0030182","GO:0070196","GO:0000338","GO:0075522","GO:0006446","GO:0034260","GO:0070321","GO:0010972","GO:0048863","GO:0001732","GO:0001731","GO:0048140","GO:0036099","GO:0090054","GO:0090052","GO:0000715","GO:0000973","GO:0006511","GO:0000184","GO:0034613","GO:0045727","GO:0009640","GO:0006413"]}],"graph":[["NP_067280.1","NP_001404618.1",0.749],["NP_067280.1","NP_032414.1",0.629],["NP_067280.1","NP_033110.1",0.839],["NP_067280.1","NP_079869.1",0.838],["NP_067280.1","XP_006500149.1",0.579],["NP_067280.1","NP_001343340.1",0.614],["NP_033110.1","NP_001404618.1",0.72],["NP_033110.1","NP_079869.1",0.962],["NP_033110.1","XP_006500149.1",0.764],["NP_033110.1","NP_001343340.1",0.765],["NP_598694.3","NP_001404618.1",0.881],["NP_598694.3","NP_079869.1",0.919],["NP_598694.3","XP_006500149.1",0.507],["NP_001343340.1","NP_032414.1",0.738],["NP_001343340.1","NP_001404618.1",0.761],["NP_001343340.1","NP_079869.1",0.706],["NP_001343340.1","XP_006500149.1",0.588],["XP_006500149.1","NP_001404618.1",0.6],["XP_006500149.1","NP_079869.1",0.846],["NP_080527.2","NP_079869.1",0.849],["NP_079869.1","NP_001404618.1",0.649],["NP_079869.1","NP_032414.1",0.528],["NP_032414.1","NP_001404618.1",0.671]],"all_go_terms":{"GO:1990145":1,"GO:0002188":2,"GO:0001731":2,"GO:0009048":1,"GO:0002192":1,"GO:0032790":1,"GO:0006417":1,"GO:0006412":1,"GO:0031204":2,"GO:0030433":2,"GO:0007275":2,"GO:0006620":2,"GO:0006605":2,"GO:0006616":2,"GO:0043952":2,"GO:0039019":2,"GO:0030970":2,"GO:0070843":2,"GO:0006366":1,"GO:0042797":1,"GO:0006360":1,"GO:0001172":1,"GO:0006385":1,"GO:0042254":1,"GO:0006386":1,"GO:0033962":2,"GO:0045947":2,"GO:0000290":2,"GO:0010607":2,"GO:0018279":1,"GO:0030182":1,"GO:0006283":1,"GO:0036099":1,"GO:0001732":1,"GO:0048140":1,"GO:0007127":1,"GO:0048142":1,"GO:0045727":1,"GO:0090054":1,"GO:0008283":1,"GO:0010972":1,"GO:0000973":1,"GO:0034260":1,"GO:0035914":1,"GO:0043248":1,"GO:0075522":1,"GO:0000184":1,"GO:0006413":1,"GO:0090052":1,"GO:0000122":1,"GO:0000715":1,"GO:0006446":1,"GO:0006511":1,"GO:0070196":1,"GO:0070321":1,"GO:1902416":1,"GO:0071033":1,"GO:0034613":1,"GO:0000338":1,"GO:0048863":1,"GO:0009640":1,"GO:0032436":1,"GO:0075525":1,"GO:0001701":1},"recipe_readded":[]}