{"hash":"784559685590398038","title":"Drosophila metamorphosis and innate immune melanization","description":"The top GO terms point to insect development (metamorphosis, cuticle formation) and innate immunity (Toll signaling, antimicrobial peptide production, melanization). The presence of zymogen activation suggests serine protease cascades central to both melanization and Toll pathway activation, tying development with immune defense in Drosophila; despite some obsolete terms, the cluster coherently centers on metamorphosis-related processes and melanization/immune responses.","confidence":"High","size":22,"edges":2,"triangles":0,"max_degree":2,"top_function":null,"members":[{"accession":"NP_001189192.1","go_terms":[]},{"accession":"NP_651529.2","go_terms":["GO:0008363"]},{"accession":"NP_001036587.1","go_terms":[]},{"accession":"NP_001245446.1","go_terms":[]},{"accession":"NP_724625.1","go_terms":[]},{"accession":"NP_001246262.1","go_terms":[]},{"accession":"NP_001286542.1","go_terms":[]},{"accession":"NP_731817.1","go_terms":["GO:0035008","GO:0006964","GO:0035006","GO:0031638","GO:0045752"]},{"accession":"NP_001097459.1","go_terms":[]},{"accession":"NP_001260468.1","go_terms":[]},{"accession":"NP_524089.2","go_terms":["GO:0007552","GO:0035071"]},{"accession":"NP_524091.1","go_terms":["GO:0007552","GO:0035071"]},{"accession":"NP_001036758.1","go_terms":[]},{"accession":"NP_648795.2","go_terms":["GO:0007552","GO:0035071"]},{"accession":"NP_001097491.1","go_terms":[]},{"accession":"NP_476944.1","go_terms":[]},{"accession":"NP_652551.1","go_terms":[]},{"accession":"NP_996295.1","go_terms":[]},{"accession":"NP_609557.1","go_terms":["GO:1903049","GO:0032222","GO:0008362","GO:0035158","GO:0048511","GO:0045187","GO:0030431","GO:1903818"]},{"accession":"NP_001188853.1","go_terms":[]},{"accession":"NP_001189053.1","go_terms":[]},{"accession":"NP_610750.1","go_terms":[]}],"graph":[["NP_609557.1","NP_001189053.1",0.53],["NP_609557.1","NP_648795.2",0.59]],"all_go_terms":{"GO:0008363":1,"GO:0045752":1,"GO:0006964":1,"GO:0035008":1,"GO:0035006":1,"GO:0031638":1,"GO:0007552":3,"GO:0035071":3,"GO:1903049":1,"GO:1903818":1,"GO:0008362":1,"GO:0035158":1,"GO:0030431":1,"GO:0045187":1,"GO:0032222":1,"GO:0048511":1},"recipe_readded":["NP_648292.1","NP_650015.3","NP_649233.2","NP_733105.1","NP_650820.1","NP_650233.3","NP_570013.3","NP_723383.1","NP_001260012.1","NP_001246317.1","NP_729102.2","NP_660192.1","NP_649145.1","NP_608341.1","NP_001034029.2","NP_731634.2","NP_001188920.1","NP_650419.1","NP_733393.3","NP_609956.1"]}