{"hash":"1850812372857744204","title":"RNA and Protein Methyltransferases","description":"The top GO terms are dominated by methylation activities: RNA methylation (guanine-N7, rRNA, tRNA, mRNA capping) and peptidyl-arginine methylation, with an additional histone methylation term. This pattern points to a cluster of methyltransferase enzymes acting on both RNA and protein substrates, making this a coherent functional group despite a few broader terms. ","confidence":"High","size":15,"edges":41,"triangles":37,"max_degree":12,"top_function":"cytoplasmic translation","members":[{"accession":"NP_523568.2","go_terms":["GO:0009236","GO:0017000","GO:0035690","GO:0006656","GO:0019919","GO:0009102","GO:0030488","GO:0016049","GO:0018012","GO:0006744","GO:0010189","GO:0016126","GO:0043985","GO:0070476","GO:0046690","GO:0002098","GO:0000056","GO:0001300","GO:0090398","GO:0030961","GO:0006370","GO:0009877","GO:0036265","GO:0006596","GO:0000154","GO:0006353","GO:0098507"]},{"accession":"NP_609918.1","go_terms":["GO:0030488","GO:0019919","GO:0031167","GO:0018364","GO:0036068","GO:0046690","GO:0009236","GO:0006370","GO:0018026","GO:0018027","GO:0036265","GO:0009877","GO:0017000","GO:1901052","GO:0002098"]},{"accession":"NP_647896.1","go_terms":["GO:0036265","GO:0006718","GO:0035572","GO:0035573","GO:0001887","GO:0014075","GO:0002347","GO:0070555","GO:0036068","GO:0018012","GO:0018013","GO:0006972","GO:0042220","GO:0002098","GO:0019505","GO:0035902","GO:0006370","GO:0009877","GO:0046690","GO:1901052","GO:0010586","GO:1990273","GO:2000632","GO:0040031","GO:0035562","GO:1900087","GO:0009236","GO:0017000","GO:0035690","GO:0006656","GO:0019919","GO:0009102","GO:0030488","GO:0016049","GO:0006744","GO:0010189","GO:0016126","GO:0043985","GO:0070476","GO:0000056","GO:0001300","GO:0090398","GO:0030961","GO:0031167","GO:0018364","GO:0018026","GO:0018027","GO:0006596","GO:0000154"]},{"accession":"NP_650321.1","go_terms":[]},{"accession":"NP_732316.2","go_terms":["GO:0009236","GO:0017000","GO:0035690","GO:0006656","GO:0019919","GO:0009102","GO:0030488","GO:0016049","GO:0018012","GO:0006744","GO:0010189","GO:0016126","GO:0043985","GO:0070476","GO:0046690","GO:0002098","GO:0000056","GO:0001300","GO:0090398","GO:0030961","GO:0006370","GO:0009877","GO:0006479","GO:0032775","GO:0009452","GO:0080180","GO:0071167","GO:0036261","GO:0017126","GO:0031167","GO:0036265","GO:0006596","GO:0000154"]},{"accession":"NP_572148.2","go_terms":["GO:0019062","GO:0036265","GO:0002128","GO:0000466","GO:0000453","GO:0039654","GO:0039520","GO:0039694","GO:0097309","GO:0006370","GO:0000463","GO:0002181","GO:0097310","GO:0007175","GO:1904876","GO:1902570","GO:0032211","GO:0000381","GO:0051096","GO:0000390","GO:0000494","GO:1904751","GO:1904744","GO:0008380"]},{"accession":"NP_611015.1","go_terms":["GO:0070475","GO:0016049","GO:0000122","GO:0009236","GO:0018364","GO:0090398","GO:0043985","GO:0031167","GO:0019919","GO:0046690"]},{"accession":"NP_650236.1","go_terms":["GO:0006356","GO:0008033","GO:0031167","GO:0048254","GO:1990258","GO:0000494"]},{"accession":"NP_608573.1","go_terms":["GO:0019062","GO:0036265","GO:0002128","GO:0000466","GO:0000453","GO:0039654","GO:0039520","GO:0039694","GO:0097309","GO:0006370","GO:0000463","GO:0002181","GO:0097310","GO:0070131","GO:0042254","GO:0042256","GO:1902626","GO:0006355","GO:0070475","GO:0002127"]},{"accession":"NP_611690.2","go_terms":["GO:0009236","GO:0017000","GO:0035690","GO:0006656","GO:0019919","GO:0009102","GO:0030488","GO:0016049","GO:0018012","GO:0006744","GO:0010189","GO:0016126","GO:0043985","GO:0070476","GO:0046690","GO:0002098","GO:0000056","GO:0001300","GO:0090398","GO:0030961","GO:0006370","GO:0009877","GO:0006307","GO:0006281","GO:0042245","GO:0012501","GO:1990983","GO:1902445","GO:0035553","GO:0035552","GO:0006397","GO:0036265","GO:0006596","GO:0000154","GO:0009852","GO:0009835","GO:0046244","GO:0055114","GO:0009686","GO:0042318","GO:0010023","GO:0009693","GO:0010421","GO:0045487"]},{"accession":"NP_611753.4","go_terms":["GO:0016049","GO:0000122","GO:0009236","GO:0090398","GO:0043985","GO:0031167","GO:0019919"]},{"accession":"NP_001033941.1","go_terms":[]},{"accession":"NP_728821.2","go_terms":["GO:0006351","GO:0016049","GO:0000122","GO:0009236","GO:0090398","GO:0009452","GO:0043985","GO:0070901","GO:0031591","GO:0006364","GO:0034970","GO:0019919","GO:0002939"]},{"accession":"NP_477413.1","go_terms":["GO:0019062","GO:0036265","GO:0002128","GO:0000466","GO:0000453","GO:0039654","GO:0039520","GO:0039694","GO:0097309","GO:0006370","GO:0000463","GO:0002181","GO:0097310"]},{"accession":"NP_649904.2","go_terms":["GO:0030488"]}],"graph":[["NP_611690.2","NP_609918.1",0.644],["NP_611690.2","NP_647896.1",0.665],["NP_611690.2","NP_650321.1",0.608],["NP_611690.2","NP_728821.2",0.635],["NP_650236.1","NP_001033941.1",0.52],["NP_650236.1","NP_523568.2",0.609],["NP_650236.1","NP_609918.1",0.509],["NP_650236.1","NP_611753.4",0.62],["NP_650236.1","NP_647896.1",0.579],["NP_650236.1","NP_728821.2",0.601],["NP_650321.1","NP_477413.1",0.594],["NP_650321.1","NP_523568.2",0.567],["NP_650321.1","NP_608573.1",0.565],["NP_650321.1","NP_647896.1",0.599],["NP_650321.1","NP_728821.2",0.65],["NP_647896.1","NP_477413.1",0.586],["NP_647896.1","NP_523568.2",0.633],["NP_647896.1","NP_572148.2",0.643],["NP_647896.1","NP_609918.1",0.73],["NP_647896.1","NP_611753.4",0.686],["NP_647896.1","NP_732316.2",0.57],["NP_647896.1","NP_728821.2",0.796],["NP_647896.1","NP_649904.2",0.779],["NP_609918.1","NP_608573.1",0.588],["NP_609918.1","NP_728821.2",0.6],["NP_572148.2","NP_523568.2",0.572],["NP_572148.2","NP_608573.1",0.556],["NP_572148.2","NP_728821.2",0.517],["NP_611015.1","NP_611753.4",0.639],["NP_649904.2","NP_001033941.1",0.523],["NP_649904.2","NP_523568.2",0.528],["NP_649904.2","NP_728821.2",0.678],["NP_477413.1","NP_728821.2",0.704],["NP_728821.2","NP_001033941.1",0.55],["NP_728821.2","NP_523568.2",0.744],["NP_728821.2","NP_611753.4",0.74],["NP_728821.2","NP_732316.2",0.653],["NP_732316.2","NP_523568.2",0.502],["NP_001033941.1","NP_523568.2",0.549],["NP_001033941.1","NP_608573.1",0.566],["NP_001033941.1","NP_611753.4",0.519]],"all_go_terms":{"GO:0010189":4,"GO:0006353":1,"GO:0016049":7,"GO:0036265":8,"GO:0019919":8,"GO:0009877":5,"GO:0030961":4,"GO:0046690":6,"GO:0017000":5,"GO:0009102":4,"GO:0006596":4,"GO:0070476":4,"GO:0006744":4,"GO:0016126":4,"GO:0002098":5,"GO:0090398":7,"GO:0018012":4,"GO:0098507":1,"GO:0006656":4,"GO:0000154":4,"GO:0043985":7,"GO:0000056":4,"GO:0035690":4,"GO:0001300":4,"GO:0006370":8,"GO:0030488":6,"GO:0009236":8,"GO:0018364":3,"GO:0018027":2,"GO:0031167":6,"GO:1901052":2,"GO:0036068":2,"GO:0018026":2,"GO:0035902":1,"GO:0019505":1,"GO:0040031":1,"GO:0018013":1,"GO:0035562":1,"GO:0070555":1,"GO:0035572":1,"GO:0006718":1,"GO:0042220":1,"GO:0035573":1,"GO:0002347":1,"GO:0010586":1,"GO:1900087":1,"GO:0001887":1,"GO:0014075":1,"GO:0006972":1,"GO:1990273":1,"GO:2000632":1,"GO:0036261":1,"GO:0017126":1,"GO:0006479":1,"GO:0009452":2,"GO:0080180":1,"GO:0032775":1,"GO:0071167":1,"GO:0000381":1,"GO:1904876":1,"GO:0000463":3,"GO:0000390":1,"GO:0002128":3,"GO:0051096":1,"GO:1904744":1,"GO:0002181":3,"GO:0007175":1,"GO:0039694":3,"GO:0097310":3,"GO:0097309":3,"GO:1904751":1,"GO:0008380":1,"GO:0000466":3,"GO:0032211":1,"GO:0000494":2,"GO:0039520":3,"GO:0019062":3,"GO:0039654":3,"GO:1902570":1,"GO:0000453":3,"GO:0070475":2,"GO:0000122":3,"GO:0048254":1,"GO:1990258":1,"GO:0006356":1,"GO:0008033":1,"GO:0070131":1,"GO:0002127":1,"GO:0006355":1,"GO:1902626":1,"GO:0042254":1,"GO:0042256":1,"GO:0035553":1,"GO:0046244":1,"GO:1902445":1,"GO:0010023":1,"GO:0009693":1,"GO:0042245":1,"GO:0055114":1,"GO:0042318":1,"GO:0012501":1,"GO:0006281":1,"GO:0045487":1,"GO:0006397":1,"GO:0009686":1,"GO:1990983":1,"GO:0009835":1,"GO:0010421":1,"GO:0035552":1,"GO:0006307":1,"GO:0009852":1,"GO:0006364":1,"GO:0006351":1,"GO:0070901":1,"GO:0002939":1,"GO:0034970":1,"GO:0031591":1},"recipe_readded":[]}