{"hash":"1763096057265867087","title":"Translation Machinery and mRNA Decay","description":"The dominant GO terms center on core and regulatory aspects of protein synthesis\u2014translation in general, initiation, elongation, termination, and even selenocysteine incorporation\u2014along with RNA turnover via deadenylation-dependent decay and related RNA regulation. A few outliers (e.g., glial proliferation) are less representative, so the overall theme is translation and post-transcriptional RNA control.","confidence":"High","size":19,"edges":153,"triangles":816,"max_degree":17,"top_function":"ribosome biogenesis","members":[{"accession":"NP_651128.1","go_terms":["GO:0007430","GO:0007034","GO:0015991","GO:0035675","GO:0042777","GO:0039022"]},{"accession":"NP_651867.2","go_terms":["GO:0071028","GO:0008033","GO:0071042","GO:0016120","GO:0097222","GO:0000962","GO:0070478","GO:0000964","GO:0034475","GO:0034476","GO:2000627","GO:0071051","GO:0071035","GO:0034473","GO:0071039","GO:0071038","GO:0000467","GO:0070481","GO:0045006","GO:0010323","GO:0035928","GO:0070651","GO:0000958","GO:0090503"]},{"accession":"NP_001097656.1","go_terms":["GO:0019082","GO:0071169","GO:1904815","GO:0039548","GO:0039520","GO:0039648","GO:0033128","GO:0060701","GO:0039579","GO:0051572","GO:0034184","GO:0007549","GO:0051725","GO:1900231","GO:0039694","GO:0061086","GO:0045618","GO:0039595","GO:1901837"]},{"accession":"NP_001260416.1","go_terms":["GO:0000288","GO:0045901","GO:0045903","GO:0014009","GO:0002184","GO:0001514","GO:0046677","GO:0070125","GO:1902802","GO:2000767","GO:0032790","GO:0006413","GO:0006412","GO:0006449","GO:0019079","GO:0001172","GO:0006415"]},{"accession":"NP_476630.1","go_terms":["GO:0032147","GO:0042254"]},{"accession":"NP_477259.1","go_terms":["GO:0010603","GO:0000288","GO:0033962","GO:1900271","GO:0030330","GO:0071347","GO:0045947","GO:0034063","GO:0002091","GO:0045671","GO:0043124","GO:0045901","GO:0045903","GO:0014009","GO:0002184","GO:0001514","GO:0046677","GO:0070125","GO:1902802","GO:2000767","GO:0032790","GO:0006413","GO:0006412","GO:0006449","GO:0019079","GO:0001172","GO:0006415"]},{"accession":"NP_477375.1","go_terms":["GO:0000288","GO:0045901","GO:0045903","GO:0014009","GO:0002184","GO:0001514","GO:0046677","GO:0070125","GO:1902802","GO:2000767","GO:0032790","GO:0006413","GO:0006412","GO:0006449","GO:0019079","GO:0001172","GO:0006415"]},{"accession":"NP_523530.1","go_terms":["GO:0006412"]},{"accession":"NP_523764.1","go_terms":["GO:0032147","GO:0042254"]},{"accession":"NP_524611.1","go_terms":["GO:0000288","GO:0045901","GO:0045903","GO:0014009","GO:0002184","GO:0001514","GO:0046677","GO:0070125","GO:1902802","GO:2000767","GO:0032790","GO:0006413","GO:0006412","GO:0006449","GO:0019079","GO:0001172","GO:0006415"]},{"accession":"NP_524752.1","go_terms":["GO:0000288","GO:0045901","GO:0045903","GO:0014009","GO:0002184","GO:0001514","GO:0046677","GO:0070125","GO:1902802","GO:2000767","GO:0032790","GO:0006413","GO:0006412","GO:0006449","GO:0019079","GO:0001172","GO:0006415"]},{"accession":"NP_524841.1","go_terms":["GO:0006425","GO:0007420","GO:0006424","GO:0006433","GO:0006412","GO:0006400"]},{"accession":"NP_610288.1","go_terms":["GO:0000288","GO:0045901","GO:0045903","GO:0014009","GO:0002184","GO:0001514","GO:0046677","GO:0070125","GO:1902802","GO:2000767","GO:0032790","GO:0006413","GO:0006412","GO:0006449","GO:0019079","GO:0001172","GO:0006415"]},{"accession":"NP_610610.1","go_terms":["GO:0031118","GO:0031120","GO:0042254","GO:1904874","GO:0000469","GO:0007004"]},{"accession":"NP_649603.3","go_terms":["GO:0045901","GO:0006412","GO:0014009","GO:0001514","GO:0046677","GO:0000288","GO:2000767","GO:0006413","GO:0006415"]},{"accession":"NP_651576.1","go_terms":["GO:2000032","GO:0090506","GO:0031581","GO:0000028","GO:0034198","GO:0006407"]},{"accession":"NP_651621.2","go_terms":["GO:0006576","GO:0000747","GO:0042274","GO:0000055","GO:0042254","GO:1901001","GO:0002181","GO:1903833","GO:0051301","GO:0006400","GO:0090529","GO:0007049","GO:0021532","GO:0070830","GO:0007612","GO:0021830","GO:0034379","GO:0001822","GO:0055108","GO:0097499","GO:0034629","GO:0007021","GO:0045176","GO:0006888","GO:0045956","GO:0000042","GO:1990386","GO:0090162","GO:0007006","GO:0000266","GO:0043001","GO:0060999","GO:2000171","GO:0097284","GO:1902953","GO:1902307","GO:0007420","GO:0006878","GO:0045197","GO:0006623","GO:0031584","GO:0034497","GO:0042461","GO:0007173","GO:0070142","GO:0007264","GO:0097212","GO:0051519","GO:0007399","GO:0007224","GO:0046909","GO:0001889","GO:1902824","GO:0006998","GO:0003400","GO:0033028","GO:0010513","GO:0021943","GO:0034976","GO:0045901","GO:0006412","GO:0014009","GO:0001514","GO:0046677","GO:0000288","GO:2000767","GO:0006413","GO:0006415","GO:0001732","GO:0055072","GO:0015684"]},{"accession":"NP_652729.2","go_terms":["GO:0000747","GO:0042274","GO:0000055","GO:0042254","GO:1901001","GO:0002181","GO:1903833","GO:0051301","GO:0006400","GO:0090529","GO:0007049","GO:0000288","GO:0045901","GO:0045903","GO:0014009","GO:0002184","GO:0001514","GO:0046677","GO:0070125","GO:1902802","GO:2000767","GO:0032790","GO:0006413","GO:0006412","GO:0006449","GO:0019079","GO:0001172","GO:0002182","GO:0070966","GO:0070651","GO:0006415"]},{"accession":"NP_731993.1","go_terms":["GO:0045903","GO:0001731","GO:0006413","GO:0006412","GO:0000288","GO:0045901","GO:0014009","GO:0002184","GO:0001514","GO:0046677","GO:0070125","GO:1902802","GO:2000767","GO:0032790","GO:0006449","GO:0006415"]}],"graph":[["NP_476630.1","NP_001097656.1",0.827],["NP_476630.1","NP_001260416.1",0.802],["NP_476630.1","NP_524611.1",0.79],["NP_476630.1","NP_524752.1",0.832],["NP_476630.1","NP_524841.1",0.759],["NP_476630.1","NP_523530.1",0.746],["NP_476630.1","NP_523764.1",0.785],["NP_476630.1","NP_477259.1",0.837],["NP_476630.1","NP_477375.1",0.785],["NP_476630.1","NP_610288.1",0.837],["NP_476630.1","NP_610610.1",0.719],["NP_476630.1","NP_649603.3",0.885],["NP_476630.1","NP_651576.1",0.823],["NP_476630.1","NP_651621.2",0.812],["NP_476630.1","NP_651867.2",0.855],["NP_476630.1","NP_652729.2",0.842],["NP_476630.1","NP_731993.1",0.771],["NP_610288.1","NP_001097656.1",0.912],["NP_610288.1","NP_001260416.1",0.821],["NP_610288.1","NP_477259.1",0.853],["NP_610288.1","NP_477375.1",0.769],["NP_610288.1","NP_523530.1",0.867],["NP_610288.1","NP_523764.1",0.831],["NP_610288.1","NP_524611.1",0.775],["NP_610288.1","NP_524752.1",0.756],["NP_610288.1","NP_524841.1",0.814],["NP_610288.1","NP_610610.1",0.836],["NP_610288.1","NP_649603.3",0.863],["NP_610288.1","NP_651576.1",0.878],["NP_610288.1","NP_651621.2",0.746],["NP_610288.1","NP_651867.2",0.827],["NP_610288.1","NP_652729.2",0.856],["NP_610288.1","NP_731993.1",0.797],["NP_651576.1","NP_001097656.1",0.816],["NP_651576.1","NP_001260416.1",0.838],["NP_651576.1","NP_477259.1",0.824],["NP_651576.1","NP_477375.1",0.88],["NP_651576.1","NP_523530.1",0.774],["NP_651576.1","NP_523764.1",0.744],["NP_651576.1","NP_524611.1",0.848],["NP_651576.1","NP_524752.1",0.863],["NP_651576.1","NP_524841.1",0.842],["NP_651576.1","NP_610610.1",0.819],["NP_651576.1","NP_649603.3",0.802],["NP_651576.1","NP_651621.2",0.833],["NP_651576.1","NP_651867.2",0.82],["NP_651576.1","NP_652729.2",0.851],["NP_651576.1","NP_731993.1",0.811],["NP_001097656.1","NP_524611.1",0.866],["NP_001097656.1","NP_524752.1",0.874],["NP_001097656.1","NP_524841.1",0.72],["NP_001097656.1","NP_523530.1",0.736],["NP_001097656.1","NP_523764.1",0.726],["NP_001097656.1","NP_477259.1",0.891],["NP_001097656.1","NP_477375.1",0.889],["NP_001097656.1","NP_001260416.1",0.865],["NP_001097656.1","NP_610610.1",0.689],["NP_001097656.1","NP_731993.1",0.897],["NP_001097656.1","NP_652729.2",0.844],["NP_001097656.1","NP_651621.2",0.816],["NP_001097656.1","NP_651867.2",0.796],["NP_001097656.1","NP_649603.3",0.87],["NP_477259.1","NP_001260416.1",0.862],["NP_477259.1","NP_477375.1",0.836],["NP_477259.1","NP_523530.1",0.795],["NP_477259.1","NP_523764.1",0.87],["NP_477259.1","NP_524611.1",0.837],["NP_477259.1","NP_524752.1",0.849],["NP_477259.1","NP_524841.1",0.853],["NP_477259.1","NP_610610.1",0.842],["NP_477259.1","NP_731993.1",0.848],["NP_477259.1","NP_652729.2",0.894],["NP_477259.1","NP_651621.2",0.821],["NP_477259.1","NP_651867.2",0.842],["NP_477259.1","NP_649603.3",0.899],["NP_651867.2","NP_001260416.1",0.838],["NP_651867.2","NP_477375.1",0.809],["NP_651867.2","NP_523530.1",0.663],["NP_651867.2","NP_523764.1",0.792],["NP_651867.2","NP_524611.1",0.806],["NP_651867.2","NP_524752.1",0.807],["NP_651867.2","NP_524841.1",0.793],["NP_651867.2","NP_610610.1",0.82],["NP_651867.2","NP_649603.3",0.863],["NP_651867.2","NP_651621.2",0.791],["NP_651867.2","NP_652729.2",0.858],["NP_651867.2","NP_731993.1",0.818],["NP_524752.1","NP_001260416.1",0.822],["NP_524752.1","NP_477375.1",0.777],["NP_524752.1","NP_523530.1",0.871],["NP_524752.1","NP_523764.1",0.874],["NP_524752.1","NP_524611.1",0.791],["NP_524752.1","NP_524841.1",0.825],["NP_524752.1","NP_610610.1",0.841],["NP_524752.1","NP_649603.3",0.869],["NP_524752.1","NP_651621.2",0.762],["NP_524752.1","NP_652729.2",0.852],["NP_524752.1","NP_731993.1",0.809],["NP_477375.1","NP_001260416.1",0.805],["NP_477375.1","NP_523530.1",0.862],["NP_477375.1","NP_523764.1",0.848],["NP_477375.1","NP_524611.1",0.766],["NP_477375.1","NP_524841.1",0.806],["NP_477375.1","NP_610610.1",0.818],["NP_477375.1","NP_731993.1",0.783],["NP_477375.1","NP_652729.2",0.854],["NP_477375.1","NP_651621.2",0.741],["NP_477375.1","NP_649603.3",0.861],["NP_524611.1","NP_001260416.1",0.812],["NP_524611.1","NP_523530.1",0.866],["NP_524611.1","NP_523764.1",0.829],["NP_524611.1","NP_524841.1",0.809],["NP_524611.1","NP_610610.1",0.797],["NP_524611.1","NP_649603.3",0.86],["NP_524611.1","NP_651621.2",0.746],["NP_524611.1","NP_652729.2",0.851],["NP_524611.1","NP_731993.1",0.784],["NP_610610.1","NP_001260416.1",0.821],["NP_610610.1","NP_523530.1",0.737],["NP_610610.1","NP_523764.1",0.72],["NP_610610.1","NP_524841.1",0.858],["NP_610610.1","NP_649603.3",0.842],["NP_610610.1","NP_651621.2",0.81],["NP_610610.1","NP_652729.2",0.833],["NP_610610.1","NP_731993.1",0.83],["NP_652729.2","NP_001260416.1",0.876],["NP_652729.2","NP_523530.1",0.817],["NP_652729.2","NP_523764.1",0.879],["NP_652729.2","NP_524841.1",0.885],["NP_652729.2","NP_649603.3",0.882],["NP_652729.2","NP_651621.2",0.837],["NP_652729.2","NP_731993.1",0.858],["NP_001260416.1","NP_523530.1",0.802],["NP_001260416.1","NP_523764.1",0.861],["NP_001260416.1","NP_524841.1",0.855],["NP_001260416.1","NP_649603.3",0.877],["NP_001260416.1","NP_651621.2",0.782],["NP_001260416.1","NP_731993.1",0.821],["NP_649603.3","NP_523530.1",0.777],["NP_649603.3","NP_523764.1",0.872],["NP_649603.3","NP_524841.1",0.878],["NP_649603.3","NP_731993.1",0.856],["NP_649603.3","NP_651621.2",0.834],["NP_524841.1","NP_523530.1",0.759],["NP_524841.1","NP_523764.1",0.776],["NP_524841.1","NP_651621.2",0.809],["NP_524841.1","NP_731993.1",0.838],["NP_523764.1","NP_523530.1",0.733],["NP_523764.1","NP_651621.2",0.835],["NP_523764.1","NP_731993.1",0.851],["NP_731993.1","NP_523530.1",0.75],["NP_731993.1","NP_651621.2",0.771],["NP_523530.1","NP_651621.2",0.748]],"all_go_terms":{"GO:0007430":1,"GO:0007034":1,"GO:0015991":1,"GO:0035675":1,"GO:0039022":1,"GO:0042777":1,"GO:0071039":1,"GO:0070478":1,"GO:0071028":1,"GO:0071035":1,"GO:0008033":1,"GO:2000627":1,"GO:0071042":1,"GO:0016120":1,"GO:0000958":1,"GO:0000467":1,"GO:0034476":1,"GO:0090503":1,"GO:0070481":1,"GO:0097222":1,"GO:0045006":1,"GO:0034473":1,"GO:0071051":1,"GO:0034475":1,"GO:0000964":1,"GO:0035928":1,"GO:0010323":1,"GO:0000962":1,"GO:0071038":1,"GO:0070651":2,"GO:0045618":1,"GO:0039595":1,"GO:0007549":1,"GO:0060701":1,"GO:0061086":1,"GO:0019082":1,"GO:0051725":1,"GO:0071169":1,"GO:0051572":1,"GO:0039548":1,"GO:0039648":1,"GO:0039694":1,"GO:0034184":1,"GO:0033128":1,"GO:1901837":1,"GO:1904815":1,"GO:0039579":1,"GO:0039520":1,"GO:1900231":1,"GO:0019079":7,"GO:0046677":10,"GO:1902802":8,"GO:0006413":10,"GO:0000288":10,"GO:0002184":8,"GO:0032790":8,"GO:0006449":8,"GO:0045903":8,"GO:0006412":12,"GO:0001514":10,"GO:0001172":7,"GO:0006415":10,"GO:2000767":10,"GO:0014009":10,"GO:0045901":10,"GO:0070125":8,"GO:0042254":5,"GO:0032147":2,"GO:0010603":1,"GO:0030330":1,"GO:0034063":1,"GO:1900271":1,"GO:0002091":1,"GO:0033962":1,"GO:0043124":1,"GO:0071347":1,"GO:0045947":1,"GO:0045671":1,"GO:0006424":1,"GO:0006400":3,"GO:0006425":1,"GO:0007420":2,"GO:0006433":1,"GO:0007004":1,"GO:0031120":1,"GO:1904874":1,"GO:0031118":1,"GO:0000469":1,"GO:0031581":1,"GO:0034198":1,"GO:0090506":1,"GO:2000032":1,"GO:0006407":1,"GO:0000028":1,"GO:0000747":2,"GO:1902953":1,"GO:0021830":1,"GO:0007021":1,"GO:0001822":1,"GO:0034497":1,"GO:0000266":1,"GO:0021532":1,"GO:0034379":1,"GO:0006623":1,"GO:0007612":1,"GO:1902824":1,"GO:0051301":2,"GO:0007049":2,"GO:0007264":1,"GO:0007006":1,"GO:0042274":2,"GO:0006878":1,"GO:0003400":1,"GO:0097284":1,"GO:0001889":1,"GO:0060999":1,"GO:0045197":1,"GO:0097499":1,"GO:0090529":2,"GO:0045956":1,"GO:0042461":1,"GO:0007399":1,"GO:1903833":2,"GO:0006888":1,"GO:0000042":1,"GO:1990386":1,"GO:0007224":1,"GO:0070142":1,"GO:0015684":1,"GO:0046909":1,"GO:1902307":1,"GO:0055108":1,"GO:0043001":1,"GO:0007173":1,"GO:0033028":1,"GO:0010513":1,"GO:0002181":2,"GO:1901001":2,"GO:0045176":1,"GO:0001732":1,"GO:0055072":1,"GO:2000171":1,"GO:0031584":1,"GO:0006998":1,"GO:0097212":1,"GO:0006576":1,"GO:0034629":1,"GO:0090162":1,"GO:0051519":1,"GO:0021943":1,"GO:0034976":1,"GO:0070830":1,"GO:0000055":2,"GO:0002182":1,"GO:0070966":1,"GO:0001731":1},"recipe_readded":[]}