{"hash":"175547003831770560","title":"Retroviral replication and proviral latency","description":"This cluster centers on the retroviral life cycle and proviral latency, with GO terms for viral release, viral life cycle, RNA-templated DNA biosynthetic process, host-driven activation of viral genome replication, and establishment of integrated proviral latency. A few terms related to protein folding and isomerization appear, likely reflecting host chaperone involvement during viral replication. Overall, the dominant theme is the interaction between host cells and retroviruses, covering replication, integration, and latency maintenance.","confidence":"High","size":23,"edges":5,"triangles":1,"max_degree":3,"top_function":"protein folding","members":[{"accession":"NP_001163154.1","go_terms":[]},{"accession":"NP_651838.1","go_terms":["GO:0008053","GO:0042407"]},{"accession":"NP_001259392.1","go_terms":[]},{"accession":"NP_476656.1","go_terms":["GO:0019061","GO:0006457","GO:0019064","GO:0019068","GO:0030260","GO:0050900","GO:0010849","GO:0000413","GO:0075713","GO:0019076","GO:0019058","GO:0044829","GO:0048453","GO:2000276","GO:0071492","GO:0034389","GO:0006278","GO:0050714","GO:1901407"]},{"accession":"NP_001097900.2","go_terms":[]},{"accession":"NP_523874.1","go_terms":["GO:0019061","GO:0006457","GO:0019064","GO:0019068","GO:0030260","GO:0050900","GO:0010849","GO:0000413","GO:0075713","GO:0019076","GO:0019058","GO:0044829","GO:0048453","GO:2000276","GO:0071492","GO:0034389","GO:0006278","GO:0050714","GO:1901407"]},{"accession":"NP_610023.1","go_terms":["GO:0070276","GO:0042391","GO:0000305","GO:0019383","GO:0043448","GO:0006550","GO:0009106","GO:0006212","GO:0048240","GO:0006096","GO:0051068","GO:0043046","GO:0007369","GO:0036245","GO:0006749","GO:0009228","GO:0019646","GO:0046653","GO:0045454","GO:0042128","GO:0007568","GO:0097054","GO:0006552","GO:0042208","GO:0006120","GO:0019430","GO:0050787","GO:0010731","GO:0006103","GO:0006214","GO:0019483"]},{"accession":"NP_610740.1","go_terms":["GO:0042273","GO:0006413"]},{"accession":"NP_611695.1","go_terms":["GO:0019061","GO:0006457","GO:0019064","GO:0019068","GO:0030260","GO:0050900","GO:0010849","GO:0000413","GO:0075713","GO:0019076","GO:0019058","GO:0044829","GO:0048453","GO:2000276","GO:0071492","GO:0034389","GO:0006278","GO:0050714","GO:1901407"]},{"accession":"NP_649465.6","go_terms":["GO:0016567","GO:0051260","GO:0050966","GO:0019228","GO:0035024","GO:1900454","GO:0060081","GO:0071435","GO:1902260","GO:0043149","GO:0050976","GO:0021759","GO:0021633","GO:0060372","GO:0045188","GO:0044335","GO:0071286","GO:0098914","GO:0086091","GO:2000372","GO:0006836"]},{"accession":"NP_523787.2","go_terms":["GO:0050830"]},{"accession":"NP_609747.1","go_terms":["GO:0090502","GO:0019740","GO:0030324","GO:0007420","GO:0046360","GO:0001822","GO:0006212","GO:0070689","GO:0017148","GO:0070314","GO:0009097","GO:0050680","GO:1902074"]},{"accession":"NP_001356917.1","go_terms":["GO:0006360","GO:0070816","GO:0006289"]},{"accession":"NP_649778.1","go_terms":[]},{"accession":"NP_996437.1","go_terms":[]},{"accession":"NP_001014602.1","go_terms":["GO:0016079","GO:0046928","GO:0006836","GO:0031915","GO:0030073"]},{"accession":"NP_524391.2","go_terms":["GO:0050830"]},{"accession":"NP_610833.1","go_terms":[]},{"accession":"NP_611510.1","go_terms":[]},{"accession":"NP_647633.1","go_terms":["GO:0007030","GO:0030324","GO:0034605","GO:0006606"]},{"accession":"NP_651433.1","go_terms":[]},{"accession":"NP_649460.3","go_terms":["GO:0030218","GO:0055072"]},{"accession":"NP_723383.1","go_terms":["GO:1901482","GO:1901481","GO:0006867","GO:0090452","GO:0090513","GO:0090515","GO:0090514","GO:0090517","GO:0090516","GO:0090518","GO:1990818","GO:0051365","GO:0048829","GO:0089707","GO:0061402","GO:0089708","GO:2000487","GO:0015824","GO:0015808"]}],"graph":[["NP_476656.1","NP_523874.1",0.539],["NP_476656.1","NP_610023.1",0.639],["NP_476656.1","NP_611695.1",0.673],["NP_611695.1","NP_523874.1",0.587],["NP_647633.1","NP_001163154.1",0.61]],"all_go_terms":{"GO:0042407":1,"GO:0008053":1,"GO:2000276":3,"GO:0006457":3,"GO:1901407":3,"GO:0019076":3,"GO:0019058":3,"GO:0000413":3,"GO:0006278":3,"GO:0044829":3,"GO:0075713":3,"GO:0071492":3,"GO:0050714":3,"GO:0019064":3,"GO:0048453":3,"GO:0050900":3,"GO:0019061":3,"GO:0034389":3,"GO:0010849":3,"GO:0030260":3,"GO:0019068":3,"GO:0019383":1,"GO:0007568":1,"GO:0042208":1,"GO:0070276":1,"GO:0006550":1,"GO:0050787":1,"GO:0048240":1,"GO:0010731":1,"GO:0006212":2,"GO:0043448":1,"GO:0006103":1,"GO:0019483":1,"GO:0097054":1,"GO:0051068":1,"GO:0009228":1,"GO:0045454":1,"GO:0009106":1,"GO:0006749":1,"GO:0006214":1,"GO:0043046":1,"GO:0019646":1,"GO:0006552":1,"GO:0042391":1,"GO:0006120":1,"GO:0036245":1,"GO:0007369":1,"GO:0046653":1,"GO:0042128":1,"GO:0000305":1,"GO:0019430":1,"GO:0006096":1,"GO:0042273":1,"GO:0006413":1,"GO:0071286":1,"GO:0050976":1,"GO:0071435":1,"GO:0035024":1,"GO:0086091":1,"GO:0051260":1,"GO:0019228":1,"GO:0045188":1,"GO:0006836":2,"GO:0016567":1,"GO:0060372":1,"GO:0044335":1,"GO:1900454":1,"GO:2000372":1,"GO:0021759":1,"GO:0060081":1,"GO:0043149":1,"GO:0021633":1,"GO:1902260":1,"GO:0050966":1,"GO:0098914":1,"GO:0050830":2,"GO:0009097":1,"GO:0030324":2,"GO:0019740":1,"GO:0001822":1,"GO:1902074":1,"GO:0050680":1,"GO:0017148":1,"GO:0070689":1,"GO:0046360":1,"GO:0070314":1,"GO:0007420":1,"GO:0090502":1,"GO:0006360":1,"GO:0070816":1,"GO:0006289":1,"GO:0030073":1,"GO:0031915":1,"GO:0016079":1,"GO:0046928":1,"GO:0034605":1,"GO:0007030":1,"GO:0006606":1,"GO:0030218":1,"GO:0055072":1,"GO:0090514":1,"GO:0090515":1,"GO:1990818":1,"GO:0015808":1,"GO:0090516":1,"GO:0015824":1,"GO:0048829":1,"GO:0090518":1,"GO:0051365":1,"GO:2000487":1,"GO:0061402":1,"GO:0006867":1,"GO:1901481":1,"GO:0090517":1,"GO:1901482":1,"GO:0090452":1,"GO:0090513":1,"GO:0089708":1,"GO:0089707":1},"recipe_readded":["NP_722780.1","NP_650156.1","NP_650016.1","NP_648501.1","NP_573255.1","NP_728982.1","NP_648757.1","NP_650055.1","NP_001247298.1","NP_732519.3","NP_001163658.1","NP_726762.1","NP_511110.1","NP_650891.1","NP_476951.1","NP_511109.1","NP_648082.1","NP_608668.2","NP_476808.1","NP_001036277.2"]}