{"hash":"1573870423037419997","title":"Ribosome Biogenesis and Translational Fidelity","description":"This cluster is centered on core ribosome-related processes: translation (cytoplasmic), ribosome biogenesis, and large subunit assembly, with multiple terms addressing translational fidelity and its regulation/maintenance. These together point to a group of proteins involved in ribosome production and ensuring accurate protein synthesis, with occasional peripheral links to antibiotic response that can reflect ribosome-associated stress pathways. ","confidence":"High","size":25,"edges":261,"triangles":1699,"max_degree":23,"top_function":"ribosome biogenesis","members":[{"accession":"NP_572178.1","go_terms":["GO:0061738","GO:0031117","GO:0051260","GO:0030420","GO:2001171","GO:0034214","GO:1903862","GO:0032968","GO:0070842","GO:0001824","GO:0006260","GO:0034551","GO:0070682","GO:0033314","GO:0032979","GO:0051013","GO:0046034","GO:1901800","GO:1990171","GO:0016485","GO:0045899","GO:0030968","GO:0006272","GO:0070987","GO:0043335","GO:0070676","GO:0070370","GO:1903007","GO:0090261","GO:0070914","GO:0061641","GO:0061166","GO:1903715","GO:0051301","GO:0006888","GO:0045053","GO:0001319","GO:0035494","GO:0019079","GO:0070414","GO:0097352","GO:0071218","GO:0016562","GO:2000158","GO:0070389","GO:0018279","GO:0006406","GO:0051131","GO:0048219","GO:0030433","GO:1903724","GO:0034599","GO:0090296","GO:0072389","GO:0045041","GO:0016558","GO:0000733","GO:0070407","GO:0070651","GO:0071712","GO:0035617","GO:0031412","GO:0003341","GO:1990048","GO:0000027","GO:1904287","GO:0006351","GO:0034975","GO:0042053","GO:0048085","GO:0000338","GO:1903741","GO:0051584","GO:0008057","GO:0031175","GO:0007155","GO:0048489","GO:0007504","GO:0045104","GO:0051085","GO:1900244","GO:0006998","GO:0044319","GO:0071763","GO:0007029","GO:0072321","GO:2000008","GO:0043104"]},{"accession":"NP_001036440.1","go_terms":["GO:0042474","GO:0007605","GO:0048318","GO:0001501","GO:0001503","GO:0034463","GO:0006412"]},{"accession":"NP_001036652.1","go_terms":["GO:0045903","GO:0042254","GO:0006412","GO:1990145","GO:0046677","GO:0006407"]},{"accession":"NP_001189261.2","go_terms":["GO:0009585","GO:0006355","GO:0042753","GO:0010018"]},{"accession":"NP_001189263.2","go_terms":[]},{"accession":"NP_001261677.1","go_terms":[]},{"accession":"NP_476629.1","go_terms":["GO:0002181"]},{"accession":"NP_476874.1","go_terms":["GO:0045903","GO:0042254","GO:0006412","GO:1990145","GO:0046677","GO:0006407"]},{"accession":"NP_523382.1","go_terms":["GO:0006450","GO:0006412","GO:0006407"]},{"accession":"NP_523774.1","go_terms":["GO:0097327","GO:0006412","GO:0000027"]},{"accession":"NP_523889.1","go_terms":["GO:0006412","GO:0000027"]},{"accession":"NP_524022.1","go_terms":["GO:0002181","GO:1990090","GO:0032543"]},{"accession":"NP_524053.2","go_terms":["GO:0045727","GO:0006412","GO:1902164","GO:1902167","GO:0032784","GO:0006977","GO:1904803","GO:0042273","GO:0031564","GO:0071480","GO:0006354","GO:0006353","GO:0006437","GO:0045903","GO:0034605","GO:1990145","GO:0046677","GO:0000455","GO:0042254","GO:0006351","GO:0045947"]},{"accession":"NP_524185.1","go_terms":["GO:0046677","GO:0006412","GO:0046898"]},{"accession":"NP_524316.1","go_terms":["GO:0071353","GO:0006412","GO:0000027"]},{"accession":"NP_524706.2","go_terms":[]},{"accession":"NP_524884.1","go_terms":["GO:0042254","GO:0000028","GO:0000462","GO:0006412"]},{"accession":"NP_609366.2","go_terms":["GO:0006355","GO:0006351"]},{"accession":"NP_610503.1","go_terms":["GO:0006450","GO:0006412"]},{"accession":"NP_610554.1","go_terms":["GO:0006614","GO:0071353","GO:0042254","GO:0002181","GO:0000027"]},{"accession":"NP_610615.1","go_terms":["GO:0008033","GO:0033962","GO:0008334","GO:0070317","GO:0051170","GO:1990141","GO:0009414","GO:0042633","GO:0000245","GO:0000387","GO:0000290","GO:0009737","GO:0030490","GO:0006369","GO:0045292"]},{"accession":"NP_648091.1","go_terms":["GO:0042254","GO:0006412"]},{"accession":"NP_649560.1","go_terms":["GO:1901194","GO:0006412"]},{"accession":"NP_650407.1","go_terms":["GO:0006450","GO:0006412","GO:0006407"]},{"accession":"NP_001189260.2","go_terms":[]}],"graph":[["NP_001036440.1","NP_001036652.1",0.77],["NP_001036440.1","NP_001189260.2",0.687],["NP_001036440.1","NP_001189261.2",0.677],["NP_001036440.1","NP_001189263.2",0.716],["NP_001036440.1","NP_001261677.1",0.639],["NP_001036440.1","NP_476629.1",0.783],["NP_001036440.1","NP_476874.1",0.746],["NP_001036440.1","NP_523382.1",0.785],["NP_001036440.1","NP_523774.1",0.701],["NP_001036440.1","NP_523889.1",0.735],["NP_001036440.1","NP_524022.1",0.756],["NP_001036440.1","NP_524053.2",0.762],["NP_001036440.1","NP_524185.1",0.755],["NP_001036440.1","NP_524316.1",0.764],["NP_001036440.1","NP_524706.2",0.603],["NP_001036440.1","NP_524884.1",0.766],["NP_001036440.1","NP_609366.2",0.796],["NP_001036440.1","NP_610503.1",0.682],["NP_001036440.1","NP_610554.1",0.75],["NP_001036440.1","NP_610615.1",0.788],["NP_001036440.1","NP_648091.1",0.686],["NP_001036440.1","NP_649560.1",0.716],["NP_001036440.1","NP_650407.1",0.769],["NP_524185.1","NP_001036652.1",0.747],["NP_524185.1","NP_001189260.2",0.828],["NP_524185.1","NP_001189261.2",0.72],["NP_524185.1","NP_001189263.2",0.759],["NP_524185.1","NP_476629.1",0.772],["NP_524185.1","NP_476874.1",0.773],["NP_524185.1","NP_523382.1",0.784],["NP_524185.1","NP_523774.1",0.793],["NP_524185.1","NP_523889.1",0.788],["NP_524185.1","NP_524022.1",0.639],["NP_524185.1","NP_524053.2",0.877],["NP_524185.1","NP_524316.1",0.579],["NP_524185.1","NP_524884.1",0.704],["NP_524185.1","NP_648091.1",0.769],["NP_524185.1","NP_610503.1",0.645],["NP_524185.1","NP_610554.1",0.56],["NP_524185.1","NP_610615.1",0.594],["NP_524185.1","NP_650407.1",0.71],["NP_524185.1","NP_649560.1",0.748],["NP_523889.1","NP_001036652.1",0.747],["NP_523889.1","NP_001189260.2",0.79],["NP_523889.1","NP_001189261.2",0.711],["NP_523889.1","NP_001189263.2",0.688],["NP_523889.1","NP_001261677.1",0.519],["NP_523889.1","NP_476629.1",0.821],["NP_523889.1","NP_476874.1",0.762],["NP_523889.1","NP_523382.1",0.743],["NP_523889.1","NP_523774.1",0.753],["NP_523889.1","NP_524022.1",0.697],["NP_523889.1","NP_524053.2",0.726],["NP_523889.1","NP_524316.1",0.707],["NP_523889.1","NP_524706.2",0.519],["NP_523889.1","NP_524884.1",0.795],["NP_523889.1","NP_648091.1",0.741],["NP_523889.1","NP_610503.1",0.737],["NP_523889.1","NP_610554.1",0.675],["NP_523889.1","NP_610615.1",0.697],["NP_523889.1","NP_609366.2",0.806],["NP_523889.1","NP_650407.1",0.762],["NP_523889.1","NP_649560.1",0.69],["NP_609366.2","NP_001036652.1",0.74],["NP_609366.2","NP_001189260.2",0.811],["NP_609366.2","NP_001189261.2",0.703],["NP_609366.2","NP_001189263.2",0.765],["NP_609366.2","NP_001261677.1",0.509],["NP_609366.2","NP_476629.1",0.871],["NP_609366.2","NP_476874.1",0.801],["NP_609366.2","NP_523382.1",0.819],["NP_609366.2","NP_523774.1",0.875],["NP_609366.2","NP_524022.1",0.829],["NP_609366.2","NP_524053.2",0.738],["NP_609366.2","NP_524706.2",0.545],["NP_609366.2","NP_524884.1",0.821],["NP_609366.2","NP_610503.1",0.8],["NP_609366.2","NP_610554.1",0.689],["NP_609366.2","NP_610615.1",0.77],["NP_609366.2","NP_648091.1",0.83],["NP_609366.2","NP_649560.1",0.803],["NP_609366.2","NP_650407.1",0.74],["NP_001189261.2","NP_001036652.1",0.712],["NP_001189261.2","NP_524706.2",0.504],["NP_001189261.2","NP_524884.1",0.697],["NP_001189261.2","NP_524022.1",0.792],["NP_001189261.2","NP_524053.2",0.858],["NP_001189261.2","NP_524316.1",0.711],["NP_001189261.2","NP_523382.1",0.788],["NP_001189261.2","NP_523774.1",0.84],["NP_001189261.2","NP_476874.1",0.754],["NP_001189261.2","NP_476629.1",0.689],["NP_001189261.2","NP_001189260.2",0.797],["NP_001189261.2","NP_001189263.2",0.691],["NP_001189261.2","NP_648091.1",0.77],["NP_001189261.2","NP_610503.1",0.599],["NP_001189261.2","NP_610554.1",0.605],["NP_001189261.2","NP_610615.1",0.701],["NP_001189261.2","NP_650407.1",0.659],["NP_001189261.2","NP_649560.1",0.756],["NP_476874.1","NP_001036652.1",0.771],["NP_476874.1","NP_001189260.2",0.813],["NP_476874.1","NP_001189263.2",0.787],["NP_476874.1","NP_001261677.1",0.55],["NP_476874.1","NP_476629.1",0.851],["NP_476874.1","NP_523382.1",0.747],["NP_476874.1","NP_523774.1",0.807],["NP_476874.1","NP_524022.1",0.803],["NP_476874.1","NP_524053.2",0.818],["NP_476874.1","NP_524316.1",0.857],["NP_476874.1","NP_524706.2",0.594],["NP_476874.1","NP_524884.1",0.843],["NP_476874.1","NP_648091.1",0.811],["NP_476874.1","NP_610503.1",0.734],["NP_476874.1","NP_610554.1",0.789],["NP_476874.1","NP_610615.1",0.712],["NP_476874.1","NP_650407.1",0.748],["NP_476874.1","NP_649560.1",0.764],["NP_476629.1","NP_001036652.1",0.718],["NP_476629.1","NP_001189260.2",0.746],["NP_476629.1","NP_001189263.2",0.724],["NP_476629.1","NP_001261677.1",0.598],["NP_476629.1","NP_524706.2",0.604],["NP_476629.1","NP_524884.1",0.774],["NP_476629.1","NP_524022.1",0.815],["NP_476629.1","NP_524053.2",0.839],["NP_476629.1","NP_524316.1",0.787],["NP_476629.1","NP_523382.1",0.777],["NP_476629.1","NP_523774.1",0.806],["NP_476629.1","NP_610503.1",0.855],["NP_476629.1","NP_610554.1",0.669],["NP_476629.1","NP_610615.1",0.826],["NP_476629.1","NP_648091.1",0.842],["NP_476629.1","NP_649560.1",0.808],["NP_476629.1","NP_650407.1",0.733],["NP_524053.2","NP_001036652.1",0.808],["NP_524053.2","NP_001189260.2",0.768],["NP_524053.2","NP_001189263.2",0.763],["NP_524053.2","NP_001261677.1",0.583],["NP_524053.2","NP_523382.1",0.754],["NP_524053.2","NP_523774.1",0.777],["NP_524053.2","NP_524022.1",0.842],["NP_524053.2","NP_524316.1",0.87],["NP_524053.2","NP_524706.2",0.692],["NP_524053.2","NP_524884.1",0.714],["NP_524053.2","NP_648091.1",0.668],["NP_524053.2","NP_610503.1",0.732],["NP_524053.2","NP_610554.1",0.639],["NP_524053.2","NP_610615.1",0.787],["NP_524053.2","NP_650407.1",0.697],["NP_524053.2","NP_649560.1",0.662],["NP_001261677.1","NP_001189263.2",0.63],["NP_001261677.1","NP_523382.1",0.573],["NP_001261677.1","NP_524316.1",0.524],["NP_001261677.1","NP_524706.2",0.711],["NP_001261677.1","NP_524884.1",0.531],["NP_001261677.1","NP_610554.1",0.599],["NP_001261677.1","NP_610615.1",0.57],["NP_001261677.1","NP_648091.1",0.564],["NP_001261677.1","NP_650407.1",0.603],["NP_523774.1","NP_001036652.1",0.761],["NP_523774.1","NP_001189260.2",0.767],["NP_523774.1","NP_001189263.2",0.643],["NP_523774.1","NP_524706.2",0.576],["NP_523774.1","NP_524884.1",0.756],["NP_523774.1","NP_523382.1",0.75],["NP_523774.1","NP_524022.1",0.818],["NP_523774.1","NP_524316.1",0.826],["NP_523774.1","NP_610503.1",0.788],["NP_523774.1","NP_610554.1",0.79],["NP_523774.1","NP_610615.1",0.736],["NP_523774.1","NP_648091.1",0.724],["NP_523774.1","NP_649560.1",0.768],["NP_523774.1","NP_650407.1",0.767],["NP_610554.1","NP_001036652.1",0.709],["NP_610554.1","NP_001189260.2",0.638],["NP_610554.1","NP_001189263.2",0.66],["NP_610554.1","NP_523382.1",0.738],["NP_610554.1","NP_524022.1",0.711],["NP_610554.1","NP_524316.1",0.718],["NP_610554.1","NP_524706.2",0.673],["NP_610554.1","NP_524884.1",0.659],["NP_610554.1","NP_648091.1",0.791],["NP_610554.1","NP_610503.1",0.665],["NP_610554.1","NP_610615.1",0.774],["NP_610554.1","NP_649560.1",0.646],["NP_610554.1","NP_650407.1",0.685],["NP_524884.1","NP_001036652.1",0.709],["NP_524884.1","NP_001189260.2",0.728],["NP_524884.1","NP_001189263.2",0.758],["NP_524884.1","NP_523382.1",0.843],["NP_524884.1","NP_524316.1",0.582],["NP_524884.1","NP_524706.2",0.641],["NP_524884.1","NP_572178.1",0.701],["NP_524884.1","NP_610615.1",0.707],["NP_524884.1","NP_648091.1",0.823],["NP_524884.1","NP_649560.1",0.738],["NP_524884.1","NP_650407.1",0.655],["NP_001189263.2","NP_001036652.1",0.772],["NP_001189263.2","NP_524706.2",0.651],["NP_001189263.2","NP_524022.1",0.74],["NP_001189263.2","NP_524316.1",0.773],["NP_001189263.2","NP_523382.1",0.704],["NP_001189263.2","NP_001189260.2",0.66],["NP_001189263.2","NP_648091.1",0.706],["NP_001189263.2","NP_610503.1",0.663],["NP_001189263.2","NP_610615.1",0.765],["NP_001189263.2","NP_650407.1",0.716],["NP_001189263.2","NP_649560.1",0.743],["NP_650407.1","NP_001036652.1",0.763],["NP_650407.1","NP_001189260.2",0.597],["NP_650407.1","NP_523382.1",0.839],["NP_650407.1","NP_524022.1",0.67],["NP_650407.1","NP_524316.1",0.698],["NP_650407.1","NP_524706.2",0.597],["NP_650407.1","NP_610503.1",0.681],["NP_650407.1","NP_610615.1",0.692],["NP_650407.1","NP_648091.1",0.712],["NP_650407.1","NP_649560.1",0.802],["NP_524706.2","NP_001036652.1",0.519],["NP_524706.2","NP_523382.1",0.584],["NP_524706.2","NP_524316.1",0.574],["NP_524706.2","NP_572178.1",0.508],["NP_524706.2","NP_610503.1",0.55],["NP_524706.2","NP_610615.1",0.595],["NP_524706.2","NP_648091.1",0.632],["NP_524706.2","NP_649560.1",0.595],["NP_523382.1","NP_001036652.1",0.74],["NP_523382.1","NP_001189260.2",0.805],["NP_523382.1","NP_524022.1",0.774],["NP_523382.1","NP_524316.1",0.788],["NP_523382.1","NP_610503.1",0.692],["NP_523382.1","NP_610615.1",0.751],["NP_523382.1","NP_648091.1",0.786],["NP_523382.1","NP_649560.1",0.755],["NP_001036652.1","NP_001189260.2",0.768],["NP_001036652.1","NP_524022.1",0.789],["NP_001036652.1","NP_524316.1",0.769],["NP_001036652.1","NP_610503.1",0.722],["NP_001036652.1","NP_610615.1",0.753],["NP_001036652.1","NP_648091.1",0.776],["NP_001036652.1","NP_649560.1",0.763],["NP_610615.1","NP_001189260.2",0.717],["NP_610615.1","NP_524022.1",0.666],["NP_610615.1","NP_524316.1",0.678],["NP_610615.1","NP_648091.1",0.862],["NP_610615.1","NP_610503.1",0.545],["NP_610615.1","NP_649560.1",0.664],["NP_648091.1","NP_001189260.2",0.743],["NP_648091.1","NP_524022.1",0.707],["NP_648091.1","NP_524316.1",0.81],["NP_648091.1","NP_610503.1",0.769],["NP_648091.1","NP_649560.1",0.753],["NP_610503.1","NP_001189260.2",0.696],["NP_610503.1","NP_524316.1",0.629],["NP_610503.1","NP_649560.1",0.685],["NP_524316.1","NP_001189260.2",0.72],["NP_524316.1","NP_524022.1",0.582],["NP_524316.1","NP_649560.1",0.746],["NP_524022.1","NP_001189260.2",0.794],["NP_001189260.2","NP_649560.1",0.708]],"all_go_terms":{"GO:2000158":1,"GO:1990171":1,"GO:0043335":1,"GO:0070389":1,"GO:0016558":1,"GO:0061641":1,"GO:0045053":1,"GO:0034599":1,"GO:0008057":1,"GO:0031412":1,"GO:0070407":1,"GO:0072321":1,"GO:0001824":1,"GO:0044319":1,"GO:0007504":1,"GO:0006260":1,"GO:0035617":1,"GO:0043104":1,"GO:0001319":1,"GO:0016562":1,"GO:0061166":1,"GO:1903724":1,"GO:0051013":1,"GO:1990048":1,"GO:0016485":1,"GO:0000027":5,"GO:0031175":1,"GO:0070987":1,"GO:0045899":1,"GO:1903007":1,"GO:0035494":1,"GO:0006351":3,"GO:0048219":1,"GO:0070676":1,"GO:0070842":1,"GO:1901800":1,"GO:0051584":1,"GO:0030433":1,"GO:0030968":1,"GO:0070651":1,"GO:0097352":1,"GO:0034551":1,"GO:0034214":1,"GO:0070914":1,"GO:0046034":1,"GO:0045041":1,"GO:0033314":1,"GO:0048085":1,"GO:0051260":1,"GO:0051301":1,"GO:0071218":1,"GO:1903862":1,"GO:1903715":1,"GO:0051131":1,"GO:1904287":1,"GO:0045104":1,"GO:0034975":1,"GO:0006888":1,"GO:0090261":1,"GO:0032968":1,"GO:1903741":1,"GO:0051085":1,"GO:0006998":1,"GO:0006406":1,"GO:0007029":1,"GO:0071763":1,"GO:0030420":1,"GO:2001171":1,"GO:0007155":1,"GO:0061738":1,"GO:0032979":1,"GO:0070370":1,"GO:0031117":1,"GO:0006272":1,"GO:0042053":1,"GO:2000008":1,"GO:1900244":1,"GO:0018279":1,"GO:0048489":1,"GO:0070414":1,"GO:0000338":1,"GO:0072389":1,"GO:0003341":1,"GO:0019079":1,"GO:0071712":1,"GO:0000733":1,"GO:0070682":1,"GO:0090296":1,"GO:0001501":1,"GO:0001503":1,"GO:0034463":1,"GO:0007605":1,"GO:0006412":14,"GO:0048318":1,"GO:0042474":1,"GO:0046677":4,"GO:0045903":3,"GO:0006407":4,"GO:0042254":6,"GO:1990145":3,"GO:0009585":1,"GO:0010018":1,"GO:0006355":2,"GO:0042753":1,"GO:0002181":3,"GO:0006450":3,"GO:0097327":1,"GO:1990090":1,"GO:0032543":1,"GO:0042273":1,"GO:0006353":1,"GO:0034605":1,"GO:0000455":1,"GO:0006437":1,"GO:0071480":1,"GO:1902164":1,"GO:1902167":1,"GO:1904803":1,"GO:0006354":1,"GO:0045727":1,"GO:0006977":1,"GO:0032784":1,"GO:0045947":1,"GO:0031564":1,"GO:0046898":1,"GO:0071353":2,"GO:0000462":1,"GO:0000028":1,"GO:0006614":1,"GO:0008334":1,"GO:0006369":1,"GO:1990141":1,"GO:0009737":1,"GO:0051170":1,"GO:0000290":1,"GO:0030490":1,"GO:0009414":1,"GO:0000387":1,"GO:0042633":1,"GO:0045292":1,"GO:0000245":1,"GO:0070317":1,"GO:0033962":1,"GO:0008033":1,"GO:1901194":1},"recipe_readded":[]}