{"hash":"1031996700506107519","title":"Immune signaling downregulation via deubiquitination","description":"Top GO terms cluster around negative regulation of multiple immune signaling pathways (TLR3, CD40, NOD2) and dampening of inflammatory responses. The inclusion of ubiquitin-specific deubiquitination terms (K63- and K6-linked) aligns with mechanisms that attenuate signaling cascades. B-1 B cell homeostasis and mucosal immune response terms suggest a broader role in regulating immune activity, especially at mucosal sites.","confidence":"High","size":4,"edges":4,"triangles":1,"max_degree":3,"top_function":null,"members":[{"accession":"CAG5095157.1","go_terms":["GO:1902042","GO:2000347","GO:2000349","GO:0071108","GO:0071947","GO:1990167","GO:0032495","GO:1990168","GO:0002385","GO:0002677","GO:0070433","GO:0035871","GO:0032691","GO:0043124","GO:0070536","GO:0032703","GO:2000352","GO:0001922","GO:0002634","GO:0034140","GO:0035523","GO:0034148","GO:0072573","GO:0044313","GO:0070429","GO:0032717","GO:0016567"]},{"accession":"CAG5100139.1","go_terms":["GO:0071226","GO:2000502","GO:0072177","GO:0001502","GO:0050901","GO:0072287","GO:0036303","GO:0001867","GO:0051873","GO:0002223","GO:0060355","GO:0090238","GO:0072218","GO:0006910","GO:0090403","GO:0038094","GO:0072237","GO:0010572","GO:0045575"]},{"accession":"CAG5081511.1","go_terms":[]},{"accession":"CAG5114189.1","go_terms":[]}],"graph":[["CAG5100139.1","CAG5081511.1",0.598],["CAG5095157.1","CAG5081511.1",0.977],["CAG5095157.1","CAG5114189.1",0.747],["CAG5081511.1","CAG5114189.1",0.858]],"all_go_terms":{"GO:0034140":1,"GO:2000349":1,"GO:0071947":1,"GO:1902042":1,"GO:0032691":1,"GO:0070433":1,"GO:0070536":1,"GO:0044313":1,"GO:0001922":1,"GO:0002385":1,"GO:0032717":1,"GO:1990167":1,"GO:0035871":1,"GO:0035523":1,"GO:0032703":1,"GO:0032495":1,"GO:0002634":1,"GO:0043124":1,"GO:0071108":1,"GO:1990168":1,"GO:0016567":1,"GO:0002677":1,"GO:2000352":1,"GO:2000347":1,"GO:0072573":1,"GO:0070429":1,"GO:0034148":1,"GO:2000502":1,"GO:0060355":1,"GO:0001867":1,"GO:0006910":1,"GO:0050901":1,"GO:0045575":1,"GO:0072287":1,"GO:0072177":1,"GO:0036303":1,"GO:0072218":1,"GO:0090238":1,"GO:0001502":1,"GO:0090403":1,"GO:0051873":1,"GO:0002223":1,"GO:0072237":1,"GO:0038094":1,"GO:0010572":1,"GO:0071226":1},"recipe_readded":[]}