{"hash":"424424097542358987","title":"Notch signaling and receptor proteolysis in development","description":"The terms strongly point to Notch pathway activity and its activation mechanism via receptor processing and proteolysis (Notch signaling pathway, Notch receptor processing, membrane protein ectodomain and intracellular domain proteolysis). Developmental terms (pharynx development, in utero embryonic development, neuroepithelial cell differentiation) suggest a broader embryonic developmental context. The presence of cilium assembly and smoothened signaling further hints at a developmental signaling network that can intersect with Notch. Overall, the cluster seems best described as Notch signaling and receptor proteolysis in development.","confidence":"Medium","size":11,"edges":10,"triangles":0,"max_degree":10,"top_function":null,"members":[{"accession":"GAB5364657.1","go_terms":["GO:0007219","GO:0034205","GO:0006509","GO:0007220","GO:0031293","GO:0060465"]},{"accession":"GAB5365060.1","go_terms":["GO:0042733","GO:0001701","GO:0060271","GO:0007224","GO:0001944","GO:0060563","GO:0043010"]},{"accession":"GAB5372583.1","go_terms":[]},{"accession":"GAB5367027.1","go_terms":[]},{"accession":"GAB5371895.1","go_terms":[]},{"accession":"GAB5361979.1","go_terms":[]},{"accession":"GAB5367086.1","go_terms":["GO:1904211","GO:0032815","GO:0038005","GO:0042676","GO:0048515","GO:0035311","GO:0034620"]},{"accession":"GAB5356644.1","go_terms":[]},{"accession":"GAB5358219.1","go_terms":[]},{"accession":"GAB5364157.1","go_terms":["GO:0006888"]},{"accession":"GAB5373381.1","go_terms":[]}],"graph":[["GAB5365060.1","GAB5364657.1",0.595],["GAB5372583.1","GAB5364657.1",0.609],["GAB5361979.1","GAB5364657.1",0.721],["GAB5373381.1","GAB5364657.1",0.747],["GAB5364157.1","GAB5364657.1",0.752],["GAB5367027.1","GAB5364657.1",0.875],["GAB5358219.1","GAB5364657.1",0.651],["GAB5364657.1","GAB5356644.1",0.839],["GAB5364657.1","GAB5371895.1",0.926],["GAB5364657.1","GAB5367086.1",0.936]],"all_go_terms":{"GO:0007219":1,"GO:0034205":1,"GO:0060465":1,"GO:0007220":1,"GO:0006509":1,"GO:0031293":1,"GO:0001701":1,"GO:0060563":1,"GO:0007224":1,"GO:0060271":1,"GO:0001944":1,"GO:0043010":1,"GO:0042733":1,"GO:0034620":1,"GO:0042676":1,"GO:0032815":1,"GO:0035311":1,"GO:0038005":1,"GO:1904211":1,"GO:0048515":1,"GO:0006888":1},"recipe_readded":[]}