{"hash":"1495662206010292082","title":"Ubiquitin-proteasome regulation and NF-\u03baB signaling","description":"The GO terms cluster around ubiquitin-related processes (deubiquitination, ubiquitin ligase activity regulation, proteasomal degradation) and proteasome assembly, with additional links to cell cycle control (G2/M regulation) and mRNA stability. They also point to immune signaling pathways, including TNF-mediated signaling and non-canonical NF-\u03baB signaling, plus Fc-epsilon receptor signaling. This combination suggests a functional module where protein turnover via the ubiquitin-proteasome system interfaces with NF-\u03baB\u2013driven immune signaling and cell-cycle regulation, rather than a single narrow process. ","confidence":"Medium","size":3,"edges":2,"triangles":0,"max_degree":2,"top_function":null,"members":[{"accession":"GAB5358352.1","go_terms":["GO:0090263","GO:0038061","GO:0033209","GO:0051437","GO:0051436","GO:0061418","GO:0080129","GO:0006521","GO:0002223","GO:0090090","GO:0050852","GO:0031146","GO:0031145","GO:0002862","GO:0010972","GO:0060071","GO:0010499","GO:0016032","GO:0010043","GO:0009651","GO:0043488","GO:0002479","GO:0046686","GO:0010950","GO:0038095","GO:0010363","GO:0016579"]},{"accession":"GAB5359263.1","go_terms":["GO:0006470","GO:0042006","GO:0030514","GO:0030512","GO:0042347","GO:0010074","GO:0046827","GO:0000173","GO:0080005","GO:0071560","GO:0061191","GO:0035970","GO:0010991"]},{"accession":"GAB5364093.1","go_terms":["GO:0000902","GO:0090084","GO:1903382","GO:1900035","GO:0000742","GO:0006880","GO:0016226","GO:1902037","GO:0070880","GO:0006260","GO:0034620","GO:0031204","GO:1903751","GO:0006616","GO:0070389"]}],"graph":[["GAB5359263.1","GAB5364093.1",0.936],["GAB5364093.1","GAB5358352.1",0.912]],"all_go_terms":{"GO:0016579":1,"GO:0051436":1,"GO:0080129":1,"GO:0033209":1,"GO:0038061":1,"GO:0010972":1,"GO:0043488":1,"GO:0010499":1,"GO:0051437":1,"GO:0038095":1,"GO:0031145":1,"GO:0002479":1,"GO:0016032":1,"GO:0009651":1,"GO:0002862":1,"GO:0010363":1,"GO:0010043":1,"GO:0010950":1,"GO:0031146":1,"GO:0006521":1,"GO:0090090":1,"GO:0050852":1,"GO:0061418":1,"GO:0046686":1,"GO:0090263":1,"GO:0002223":1,"GO:0060071":1,"GO:0046827":1,"GO:0030512":1,"GO:0042006":1,"GO:0042347":1,"GO:0010074":1,"GO:0000173":1,"GO:0071560":1,"GO:0030514":1,"GO:0035970":1,"GO:0080005":1,"GO:0061191":1,"GO:0010991":1,"GO:0006470":1,"GO:0016226":1,"GO:0000742":1,"GO:0070880":1,"GO:0006880":1,"GO:0034620":1,"GO:0070389":1,"GO:1903382":1,"GO:0000902":1,"GO:1902037":1,"GO:1900035":1,"GO:0006260":1,"GO:0031204":1,"GO:1903751":1,"GO:0006616":1,"GO:0090084":1},"recipe_readded":[]}