{"hash":"776104109159435279","title":"DNA Replication and Repair with Proviral Latency","description":"The top terms cluster around core DNA maintenance functions\u2014DNA replication, recombination, base-excision repair, and translesion synthesis\u2014plus RNA-templated DNA biosynthesis, indicating a cohesive DNA replication/repair theme. A subset of terms about viral entry and proviral latency suggests these proteins may participate in host DNA processing that viruses exploit for integration and latency, providing a plausible link between replication/repair and proviral states. Overall, the dominant signal is DNA replication/repair with an auxiliary viral integration context.","confidence":"High","size":22,"edges":127,"triangles":295,"max_degree":19,"top_function":"DNA replication","members":[{"accession":"KAL6725599.1","go_terms":["GO:0061738","GO:0031117","GO:0051260","GO:0030420","GO:2001171","GO:0034214","GO:1903862","GO:0032968","GO:0070842","GO:0001824","GO:0006260","GO:0034551","GO:0070682","GO:0033314","GO:0032979","GO:0051013","GO:0046034","GO:1901800","GO:1990171","GO:0016485","GO:0045899","GO:0030968","GO:0006272","GO:0070987","GO:0043335","GO:0070676","GO:0070370","GO:1903007","GO:0090261","GO:0070914","GO:0061641","GO:0061166","GO:1903715","GO:0051301","GO:0006888","GO:0045053","GO:0001319","GO:0035494","GO:0019079","GO:0070414","GO:0097352","GO:0071218","GO:0016562","GO:2000158","GO:0070389","GO:0018279","GO:0006406","GO:0051131","GO:0048219","GO:0030433","GO:1903724","GO:0034599","GO:0090296","GO:0072389","GO:0045041","GO:0016558","GO:0000733","GO:0070407","GO:0070651","GO:0071712","GO:0035617","GO:0090305","GO:0071897","GO:1900264","GO:0006261","GO:0007062"]},{"accession":"KAL6725994.1","go_terms":["GO:0061738","GO:0031117","GO:0051260","GO:0030420","GO:2001171","GO:0034214","GO:1903862","GO:0032968","GO:0070842","GO:0001824","GO:0006260","GO:0034551","GO:0070682","GO:0033314","GO:0032979","GO:0051013","GO:0046034","GO:1901800","GO:1990171","GO:0016485","GO:0045899","GO:0030968","GO:0006272","GO:0070987","GO:0043335","GO:0070676","GO:0070370","GO:1903007","GO:0090261","GO:0070914","GO:0061641","GO:0061166","GO:1903715","GO:0051301","GO:0006888","GO:0045053","GO:0001319","GO:0035494","GO:0019079","GO:0070414","GO:0097352","GO:0071218","GO:0016562","GO:2000158","GO:0070389","GO:0018279","GO:0006406","GO:0051131","GO:0048219","GO:0030433","GO:1903724","GO:0034599","GO:0090296","GO:0072389","GO:0045041","GO:0016558","GO:0000733","GO:0070407","GO:0070651","GO:0071712","GO:0035617","GO:0090305","GO:0071897","GO:1900264","GO:0006261","GO:0007062"]},{"accession":"KAL6727795.1","go_terms":["GO:0071494","GO:0006297","GO:0042276","GO:0070987","GO:0006261","GO:0006281","GO:0071897"]},{"accession":"KAL6733357.1","go_terms":["GO:0045892","GO:0019363","GO:0061738","GO:0031117","GO:0051260","GO:0030420","GO:2001171","GO:0034214","GO:1903862","GO:0032968","GO:0070842","GO:0001824","GO:0006260","GO:0034551","GO:0070682","GO:0033314","GO:0032979","GO:0051013","GO:0046034","GO:1901800","GO:1990171","GO:0016485","GO:0045899","GO:0030968","GO:0006272","GO:0070987","GO:0043335","GO:0070676","GO:0070370","GO:1903007","GO:0090261","GO:0070914","GO:0061641","GO:0061166","GO:1903715","GO:0051301","GO:0006888","GO:0045053","GO:0001319","GO:0035494","GO:0019079","GO:0070414","GO:0097352","GO:0071218","GO:0016562","GO:2000158","GO:0070389","GO:0018279","GO:0006406","GO:0051131","GO:0048219","GO:0030433","GO:1903724","GO:0034599","GO:0090296","GO:0072389","GO:0045041","GO:0016558","GO:0000733","GO:0070407","GO:0070651","GO:0071712","GO:0035617","GO:0046939","GO:0015937","GO:0009435","GO:0046940","GO:0009423","GO:0016310","GO:0046177","GO:0019632","GO:0009073"]},{"accession":"KAL6729726.1","go_terms":["GO:2000327","GO:0014912","GO:0003335","GO:2001153","GO:0045454","GO:0071375","GO:0043488","GO:0044179","GO:0006308","GO:0046856","GO:1900087","GO:0090502","GO:0006284","GO:0070301","GO:2000466","GO:0006915","GO:1903507","GO:0006310","GO:0080111","GO:0007568","GO:0071320","GO:0042493"]},{"accession":"KAL6727862.1","go_terms":["GO:0051123","GO:1903357","GO:0006413","GO:0070893","GO:0007283","GO:0045893","GO:0006352","GO:0042790","GO:0070898","GO:0006383","GO:0006359"]},{"accession":"KAL6731621.1","go_terms":["GO:0018106","GO:0045920","GO:0061508","GO:0002762","GO:0030819","GO:0006228","GO:0046777","GO:0048515","GO:0071333","GO:0045618","GO:0051259","GO:0071398","GO:0048550","GO:0070301","GO:0006241","GO:0050765","GO:0010976","GO:0006187","GO:0006186","GO:0006183","GO:0006897","GO:0007399","GO:0060416"]},{"accession":"KAL6729112.1","go_terms":["GO:2000327","GO:0014912","GO:0003335","GO:2001153","GO:0045454","GO:0071375","GO:0043488","GO:0044179","GO:0006308","GO:0046856","GO:1900087","GO:0090502","GO:0006284","GO:0070301","GO:2000466","GO:0006915","GO:1903507","GO:0006310","GO:0080111","GO:0007568","GO:0071320","GO:0042493"]},{"accession":"KAL6742029.1","go_terms":[]},{"accession":"KAL6736951.1","go_terms":[]},{"accession":"KAL6729195.1","go_terms":["GO:0009831","GO:2001009","GO:0009663"]},{"accession":"KAL6728321.1","go_terms":["GO:0046718","GO:0006310","GO:0006278","GO:0075713","GO:0075732","GO:0015074","GO:0006260","GO:0039651","GO:1903704"]},{"accession":"KAL6726180.1","go_terms":["GO:0009831","GO:2001009","GO:0009663"]},{"accession":"KAL6736619.1","go_terms":[]},{"accession":"KAL6730127.1","go_terms":["GO:0006310","GO:0071932","GO:0000002","GO:0097046","GO:0032508","GO:0032211","GO:0044806","GO:1902983","GO:0051974","GO:0043504","GO:1903469","GO:0000723"]},{"accession":"KAL6741702.1","go_terms":["GO:0009831","GO:2001009","GO:0009663"]},{"accession":"KAL6738932.1","go_terms":["GO:0046718","GO:0006310","GO:0006278","GO:0075713","GO:0075732","GO:0015074","GO:0006260","GO:0039651","GO:1903704","GO:2000327","GO:0014912","GO:0003335","GO:2001153","GO:0045454","GO:0071375","GO:0043488","GO:0044179","GO:0006308","GO:0046856","GO:1900087","GO:0090502","GO:0006284","GO:0070301","GO:2000466","GO:0006915","GO:1903507","GO:0080111","GO:0007568","GO:0071320","GO:0042493"]},{"accession":"KAL6724337.1","go_terms":["GO:0046718","GO:0006310","GO:0006278","GO:0075713","GO:0075732","GO:0015074","GO:0006260","GO:0039651","GO:1903704"]},{"accession":"KAL6735413.1","go_terms":["GO:0046718","GO:0006310","GO:0006278","GO:0075713","GO:0075732","GO:0015074","GO:0006260","GO:0039651","GO:1903704"]},{"accession":"KAL6730597.1","go_terms":["GO:0006295","GO:0006286","GO:0045876","GO:0006284","GO:0035753","GO:0045190","GO:0090267","GO:0007613","GO:0006289","GO:0031292","GO:0002455","GO:0001302","GO:0000734","GO:0006260","GO:0016446","GO:1903469","GO:0071140"]},{"accession":"KAL6739134.1","go_terms":[]},{"accession":"KAL6741940.1","go_terms":["GO:0005975","GO:0006487"]}],"graph":[["KAL6736951.1","KAL6724337.1",0.572],["KAL6736951.1","KAL6725599.1",0.776],["KAL6736951.1","KAL6725994.1",0.541],["KAL6736951.1","KAL6726180.1",0.583],["KAL6736951.1","KAL6727862.1",0.55],["KAL6736951.1","KAL6728321.1",0.623],["KAL6736951.1","KAL6729726.1",0.511],["KAL6736951.1","KAL6730597.1",0.545],["KAL6736951.1","KAL6731621.1",0.636],["KAL6736951.1","KAL6733357.1",0.894],["KAL6736951.1","KAL6735413.1",0.648],["KAL6736951.1","KAL6738932.1",0.505],["KAL6736951.1","KAL6742029.1",0.518],["KAL6738932.1","KAL6725599.1",0.932],["KAL6738932.1","KAL6725994.1",0.882],["KAL6738932.1","KAL6726180.1",0.657],["KAL6738932.1","KAL6727795.1",0.742],["KAL6738932.1","KAL6729112.1",0.686],["KAL6738932.1","KAL6731621.1",0.724],["KAL6738932.1","KAL6733357.1",0.898],["KAL6738932.1","KAL6736619.1",0.679],["KAL6738932.1","KAL6741702.1",0.564],["KAL6738932.1","KAL6741940.1",0.586],["KAL6738932.1","KAL6742029.1",0.612],["KAL6730597.1","KAL6724337.1",0.535],["KAL6730597.1","KAL6725599.1",0.916],["KAL6730597.1","KAL6725994.1",0.905],["KAL6730597.1","KAL6726180.1",0.526],["KAL6730597.1","KAL6727795.1",0.65],["KAL6730597.1","KAL6728321.1",0.537],["KAL6730597.1","KAL6733357.1",0.775],["KAL6727862.1","KAL6725599.1",0.942],["KAL6727862.1","KAL6725994.1",0.928],["KAL6727862.1","KAL6726180.1",0.588],["KAL6727862.1","KAL6729112.1",0.668],["KAL6727862.1","KAL6727795.1",0.811],["KAL6727862.1","KAL6730127.1",0.722],["KAL6727862.1","KAL6733357.1",0.962],["KAL6727862.1","KAL6741940.1",0.647],["KAL6725994.1","KAL6724337.1",0.562],["KAL6725994.1","KAL6725599.1",0.918],["KAL6725994.1","KAL6726180.1",0.773],["KAL6725994.1","KAL6727795.1",0.722],["KAL6725994.1","KAL6728321.1",0.978],["KAL6725994.1","KAL6729112.1",0.62],["KAL6725994.1","KAL6729195.1",0.816],["KAL6725994.1","KAL6729726.1",0.762],["KAL6725994.1","KAL6730127.1",0.96],["KAL6725994.1","KAL6733357.1",0.966],["KAL6725994.1","KAL6736619.1",0.809],["KAL6725994.1","KAL6739134.1",0.972],["KAL6725994.1","KAL6741702.1",0.933],["KAL6730127.1","KAL6724337.1",0.583],["KAL6730127.1","KAL6725599.1",0.856],["KAL6730127.1","KAL6733357.1",0.951],["KAL6730127.1","KAL6735413.1",0.583],["KAL6730127.1","KAL6736619.1",0.879],["KAL6730127.1","KAL6741702.1",0.524],["KAL6730127.1","KAL6742029.1",0.569],["KAL6729726.1","KAL6724337.1",0.535],["KAL6729726.1","KAL6725599.1",0.889],["KAL6729726.1","KAL6727795.1",0.618],["KAL6729726.1","KAL6728321.1",0.783],["KAL6729726.1","KAL6729112.1",0.527],["KAL6729726.1","KAL6733357.1",0.742],["KAL6729726.1","KAL6735413.1",0.695],["KAL6729726.1","KAL6739134.1",0.503],["KAL6729726.1","KAL6741702.1",0.566],["KAL6731621.1","KAL6724337.1",0.748],["KAL6731621.1","KAL6726180.1",0.532],["KAL6731621.1","KAL6728321.1",0.873],["KAL6731621.1","KAL6729195.1",0.772],["KAL6731621.1","KAL6735413.1",0.751],["KAL6731621.1","KAL6741702.1",0.853],["KAL6724337.1","KAL6725599.1",0.718],["KAL6724337.1","KAL6726180.1",0.593],["KAL6724337.1","KAL6727795.1",0.628],["KAL6724337.1","KAL6729112.1",0.547],["KAL6724337.1","KAL6733357.1",0.904],["KAL6724337.1","KAL6741940.1",0.536],["KAL6724337.1","KAL6742029.1",0.586],["KAL6729195.1","KAL6725599.1",0.88],["KAL6729195.1","KAL6727795.1",0.545],["KAL6729195.1","KAL6733357.1",0.93],["KAL6742029.1","KAL6725599.1",0.504],["KAL6742029.1","KAL6726180.1",0.66],["KAL6742029.1","KAL6728321.1",0.509],["KAL6742029.1","KAL6729112.1",0.522],["KAL6742029.1","KAL6733357.1",0.973],["KAL6742029.1","KAL6736619.1",0.514],["KAL6742029.1","KAL6741940.1",0.741],["KAL6725599.1","KAL6726180.1",0.741],["KAL6725599.1","KAL6727795.1",0.631],["KAL6725599.1","KAL6728321.1",0.978],["KAL6725599.1","KAL6729112.1",0.894],["KAL6725599.1","KAL6733357.1",0.941],["KAL6725599.1","KAL6735413.1",0.77],["KAL6725599.1","KAL6736619.1",0.826],["KAL6725599.1","KAL6739134.1",0.981],["KAL6725599.1","KAL6741702.1",0.935],["KAL6735413.1","KAL6726180.1",0.588],["KAL6735413.1","KAL6727795.1",0.559],["KAL6735413.1","KAL6728321.1",0.694],["KAL6735413.1","KAL6729112.1",0.546],["KAL6735413.1","KAL6733357.1",0.926],["KAL6735413.1","KAL6736619.1",0.578],["KAL6735413.1","KAL6741702.1",0.534],["KAL6735413.1","KAL6741940.1",0.616],["KAL6741940.1","KAL6728321.1",0.576],["KAL6741940.1","KAL6733357.1",0.923],["KAL6736619.1","KAL6728321.1",0.55],["KAL6736619.1","KAL6733357.1",0.935],["KAL6739134.1","KAL6727795.1",0.885],["KAL6739134.1","KAL6729112.1",0.72],["KAL6739134.1","KAL6733357.1",0.972],["KAL6726180.1","KAL6729112.1",0.554],["KAL6726180.1","KAL6728321.1",0.676],["KAL6726180.1","KAL6727795.1",0.691],["KAL6726180.1","KAL6733357.1",0.901],["KAL6741702.1","KAL6727795.1",0.717],["KAL6741702.1","KAL6729112.1",0.519],["KAL6741702.1","KAL6733357.1",0.933],["KAL6727795.1","KAL6729112.1",0.845],["KAL6727795.1","KAL6728321.1",0.804],["KAL6729112.1","KAL6728321.1",0.73],["KAL6729112.1","KAL6733357.1",0.744],["KAL6733357.1","KAL6728321.1",0.962]],"all_go_terms":{"GO:0051013":3,"GO:0000733":3,"GO:0051301":3,"GO:0045053":3,"GO:0001319":3,"GO:0070651":3,"GO:0034599":3,"GO:1903007":3,"GO:0071712":3,"GO:2001171":3,"GO:0048219":3,"GO:0070987":4,"GO:0061166":3,"GO:0051131":3,"GO:0016562":3,"GO:0006272":3,"GO:1901800":3,"GO:0043335":3,"GO:0030420":3,"GO:0090296":3,"GO:0006261":3,"GO:0018279":3,"GO:0070842":3,"GO:0070414":3,"GO:0032968":3,"GO:0006260":8,"GO:0070682":3,"GO:0019079":3,"GO:0032979":3,"GO:0051260":3,"GO:0034214":3,"GO:0045899":3,"GO:0070676":3,"GO:0006888":3,"GO:0035494":3,"GO:1903724":3,"GO:1903715":3,"GO:0030433":3,"GO:0045041":3,"GO:0061641":3,"GO:0030968":3,"GO:0090305":2,"GO:0090261":3,"GO:0035617":3,"GO:0071218":3,"GO:0016485":3,"GO:0016558":3,"GO:0071897":3,"GO:1900264":2,"GO:0097352":3,"GO:2000158":3,"GO:0033314":3,"GO:0046034":3,"GO:0070389":3,"GO:1990171":3,"GO:0001824":3,"GO:0070370":3,"GO:0034551":3,"GO:0070407":3,"GO:0072389":3,"GO:0006406":3,"GO:0007062":2,"GO:0070914":3,"GO:1903862":3,"GO:0061738":3,"GO:0031117":3,"GO:0006281":1,"GO:0071494":1,"GO:0006297":1,"GO:0042276":1,"GO:0009073":1,"GO:0046940":1,"GO:0009423":1,"GO:0046939":1,"GO:0019363":1,"GO:0045892":1,"GO:0019632":1,"GO:0015937":1,"GO:0016310":1,"GO:0046177":1,"GO:0009435":1,"GO:2001153":3,"GO:0042493":3,"GO:0070301":4,"GO:0007568":3,"GO:0003335":3,"GO:2000327":3,"GO:0014912":3,"GO:0006310":7,"GO:0006308":3,"GO:0044179":3,"GO:0071320":3,"GO:0045454":3,"GO:0080111":3,"GO:0006915":3,"GO:0046856":3,"GO:2000466":3,"GO:0043488":3,"GO:1900087":3,"GO:0090502":3,"GO:0071375":3,"GO:1903507":3,"GO:0006284":4,"GO:0006359":1,"GO:0006352":1,"GO:0070893":1,"GO:0045893":1,"GO:0051123":1,"GO:0006383":1,"GO:0006413":1,"GO:0070898":1,"GO:0042790":1,"GO:1903357":1,"GO:0007283":1,"GO:0071333":1,"GO:0006186":1,"GO:0046777":1,"GO:0048550":1,"GO:0045920":1,"GO:0045618":1,"GO:0071398":1,"GO:0051259":1,"GO:0006228":1,"GO:0006183":1,"GO:0018106":1,"GO:0030819":1,"GO:0002762":1,"GO:0006241":1,"GO:0007399":1,"GO:0006897":1,"GO:0006187":1,"GO:0060416":1,"GO:0050765":1,"GO:0010976":1,"GO:0061508":1,"GO:0048515":1,"GO:2001009":3,"GO:0009663":3,"GO:0009831":3,"GO:0075732":4,"GO:0046718":4,"GO:0039651":4,"GO:0075713":4,"GO:0006278":4,"GO:0015074":4,"GO:1903704":4,"GO:0051974":1,"GO:0000002":1,"GO:0032211":1,"GO:0000723":1,"GO:0044806":1,"GO:0071932":1,"GO:0097046":1,"GO:0043504":1,"GO:1902983":1,"GO:1903469":2,"GO:0032508":1,"GO:0045190":1,"GO:0006286":1,"GO:0031292":1,"GO:0045876":1,"GO:0000734":1,"GO:0007613":1,"GO:0002455":1,"GO:0090267":1,"GO:0071140":1,"GO:0006289":1,"GO:0006295":1,"GO:0016446":1,"GO:0035753":1,"GO:0001302":1,"GO:0005975":1,"GO:0006487":1},"recipe_readded":[]}