{"hash":"2131270397285248136","title":"Proteolysis-driven Peptide Processing and Hormonal Regulation","description":"The cluster\u2019s prominent GO terms center on proteolysis, protein catabolic processes, and digestion, pointing to proteolytic processing of peptides. Several terms involve maturation of peptide hormones (angiotensin) and renin-angiotensin\u2013mediated regulation of blood volume, suggesting a peptide-processing/endocrine theme. Additional terms about antigen processing/presentation via MHC II and systemic acquired resistance indicate peptide handling relevant to immune function. While some terms (e.g., mesonephros development) are less directly tied, the unifying thread is proteolytic processing of peptides that feed into digestion, immune peptide presentation, and hormone maturation.","confidence":"Medium","size":12,"edges":24,"triangles":11,"max_degree":9,"top_function":"protein catabolic process","members":[{"accession":"KAL6723252.1","go_terms":[]},{"accession":"KAL6742819.1","go_terms":["GO:0008286","GO:0009736","GO:0090080","GO:0019762","GO:0019512","GO:0030245"]},{"accession":"KAL6736078.1","go_terms":["GO:0032225","GO:0050884","GO:0017001","GO:0046929","GO:0019243","GO:0009395","GO:0090503","GO:0046381","GO:0070291","GO:0008033","GO:0070292","GO:0018189","GO:0072684","GO:0035900","GO:0006364","GO:0006198","GO:0006401","GO:1903999","GO:0019700","GO:0030420","GO:0031126","GO:0034247","GO:0046677","GO:0098789","GO:0034414"]},{"accession":"KAL6743828.1","go_terms":["GO:0009627","GO:0030163","GO:0045493","GO:0006508","GO:0002803","GO:0007586","GO:0019886","GO:0002018","GO:0016540","GO:0001823","GO:0002003","GO:0033619","GO:0070305","GO:0042985","GO:0042756","GO:0002016","GO:0050435"]},{"accession":"KAL6743829.1","go_terms":["GO:0009627","GO:0030163","GO:0045493","GO:0006508","GO:0002803","GO:0007586","GO:0019886","GO:0002018","GO:0016540","GO:0001823","GO:0002003","GO:0033619","GO:0070305","GO:0042985","GO:0042756","GO:0002016","GO:0050435"]},{"accession":"KAL6743830.1","go_terms":["GO:0009627","GO:0030163","GO:0045493","GO:0006508","GO:0002803","GO:0007586","GO:0019886","GO:0002018","GO:0016540","GO:0001823","GO:0002003","GO:0033619","GO:0070305","GO:0042985","GO:0042756","GO:0002016","GO:0050435"]},{"accession":"KAL6744437.1","go_terms":["GO:0009627","GO:0030163","GO:0045493","GO:0006508","GO:0002803","GO:0007586","GO:0019886","GO:0002018","GO:0016540","GO:0001823","GO:0002003","GO:0033619","GO:0070305","GO:0042985","GO:0042756","GO:0002016","GO:0050435"]},{"accession":"KAL6743362.1","go_terms":["GO:0009627","GO:0030163","GO:0045493","GO:0006508","GO:0002803","GO:0007586","GO:0019886","GO:0002018","GO:0016540","GO:0001823","GO:0002003","GO:0033619","GO:0070305","GO:0042985","GO:0042756","GO:0002016","GO:0050435"]},{"accession":"KAL6744331.1","go_terms":["GO:0009627","GO:0030163","GO:0045493","GO:0006508","GO:0002803","GO:0007586","GO:0019886","GO:0002018","GO:0016540","GO:0001823","GO:0002003","GO:0033619","GO:0070305","GO:0042985","GO:0042756","GO:0002016","GO:0050435"]},{"accession":"KAL6744237.1","go_terms":["GO:0009627","GO:0030163","GO:0045493","GO:0006508","GO:0002803","GO:0007586","GO:0019886","GO:0002018","GO:0016540","GO:0001823","GO:0002003","GO:0033619","GO:0070305","GO:0042985","GO:0042756","GO:0002016","GO:0050435"]},{"accession":"KAL6738338.1","go_terms":["GO:0016049","GO:0007035","GO:0015991","GO:0000032"]},{"accession":"KAL6726161.1","go_terms":["GO:0046712","GO:0030166","GO:0006256","GO:0060465","GO:0043123"]}],"graph":[["KAL6744437.1","KAL6723252.1",0.613],["KAL6744437.1","KAL6738338.1",0.649],["KAL6723252.1","KAL6744237.1",0.762],["KAL6723252.1","KAL6743362.1",0.583],["KAL6723252.1","KAL6743829.1",0.806],["KAL6723252.1","KAL6743830.1",0.772],["KAL6736078.1","KAL6738338.1",0.764],["KAL6743362.1","KAL6738338.1",0.649],["KAL6742819.1","KAL6738338.1",0.815],["KAL6738338.1","KAL6744237.1",0.692],["KAL6738338.1","KAL6744331.1",0.654],["KAL6738338.1","KAL6743828.1",0.62],["KAL6738338.1","KAL6743829.1",0.509],["KAL6738338.1","KAL6743830.1",0.672],["KAL6744237.1","KAL6726161.1",0.874],["KAL6744237.1","KAL6744331.1",0.632],["KAL6743830.1","KAL6726161.1",0.537],["KAL6743830.1","KAL6743828.1",0.603],["KAL6743830.1","KAL6744331.1",0.659],["KAL6744331.1","KAL6726161.1",0.598],["KAL6744331.1","KAL6743828.1",0.607],["KAL6744331.1","KAL6743829.1",0.584],["KAL6743828.1","KAL6726161.1",0.673],["KAL6726161.1","KAL6743829.1",0.806]],"all_go_terms":{"GO:0019762":1,"GO:0030245":1,"GO:0009736":1,"GO:0090080":1,"GO:0008286":1,"GO:0019512":1,"GO:0090503":1,"GO:0070292":1,"GO:0006364":1,"GO:0070291":1,"GO:0008033":1,"GO:0019700":1,"GO:0019243":1,"GO:1903999":1,"GO:0034414":1,"GO:0030420":1,"GO:0072684":1,"GO:0017001":1,"GO:0031126":1,"GO:0046677":1,"GO:0034247":1,"GO:0046381":1,"GO:0035900":1,"GO:0046929":1,"GO:0032225":1,"GO:0098789":1,"GO:0009395":1,"GO:0018189":1,"GO:0006401":1,"GO:0006198":1,"GO:0050884":1,"GO:0016540":7,"GO:0002803":7,"GO:0019886":7,"GO:0009627":7,"GO:0007586":7,"GO:0001823":7,"GO:0002003":7,"GO:0006508":7,"GO:0002016":7,"GO:0030163":7,"GO:0002018":7,"GO:0042756":7,"GO:0042985":7,"GO:0045493":7,"GO:0070305":7,"GO:0033619":7,"GO:0050435":7,"GO:0015991":1,"GO:0007035":1,"GO:0000032":1,"GO:0016049":1,"GO:0046712":1,"GO:0043123":1,"GO:0030166":1,"GO:0060465":1,"GO:0006256":1},"recipe_readded":[]}