{"hash":"2094083287569798837","title":"Retroviral DNA Integration and Latency","description":"The top GO terms point to key retroviral life-cycle steps: DNA integration into the host genome, establishment of proviral latency, and RNA-templated DNA biosynthesis (reverse transcription), along with DNA replication and recombination. Additional terms like viral penetration into the host nucleus and symbiont entry reflect entry into host cells, while negative regulation of siRNA processing indicates viral interference with host RNAi defenses and mitotic nuclear membrane disassembly suggests cell-cycle\u2013related effects during infection. Together, these terms form a coherent theme around retroviral integration, latency, and host interaction.","confidence":"High","size":13,"edges":0,"triangles":0,"max_degree":0,"top_function":null,"members":[{"accession":"KAL6723946.1","go_terms":["GO:0046718","GO:0006310","GO:0006278","GO:0075713","GO:0075732","GO:0015074","GO:0006260","GO:0039651","GO:1903704"]},{"accession":"KAL6739167.1","go_terms":[]},{"accession":"KAL6724950.1","go_terms":["GO:0075713","GO:0030717","GO:0045071","GO:0015074","GO:0007084","GO:0007077"]},{"accession":"KAL6725663.1","go_terms":["GO:0050966","GO:0019228","GO:0035024","GO:1900454","GO:0060081","GO:0071435","GO:1902260","GO:0051260","GO:0043149","GO:0050976","GO:0021759","GO:0021633","GO:0060372","GO:0045188","GO:0044335","GO:0071286","GO:0098914","GO:0086091"]},{"accession":"KAL6731574.1","go_terms":[]},{"accession":"KAL6726692.1","go_terms":[]},{"accession":"KAL6726762.1","go_terms":["GO:0015074"]},{"accession":"KAL6727238.1","go_terms":[]},{"accession":"KAL6744305.1","go_terms":[]},{"accession":"KAL6731061.1","go_terms":["GO:0044211","GO:0006223","GO:0044206"]},{"accession":"KAL6724076.1","go_terms":[]},{"accession":"KAL6727519.1","go_terms":[]},{"accession":"KAL6730913.1","go_terms":[]}],"graph":[],"all_go_terms":{"GO:0075732":1,"GO:0046718":1,"GO:0039651":1,"GO:0075713":2,"GO:0006310":1,"GO:0006278":1,"GO:0006260":1,"GO:0015074":3,"GO:1903704":1,"GO:0007077":1,"GO:0007084":1,"GO:0030717":1,"GO:0045071":1,"GO:0086091":1,"GO:0019228":1,"GO:0060081":1,"GO:0045188":1,"GO:0098914":1,"GO:1902260":1,"GO:0050976":1,"GO:0044335":1,"GO:0043149":1,"GO:0071286":1,"GO:0060372":1,"GO:0071435":1,"GO:1900454":1,"GO:0050966":1,"GO:0051260":1,"GO:0035024":1,"GO:0021759":1,"GO:0021633":1,"GO:0006223":1,"GO:0044211":1,"GO:0044206":1},"recipe_readded":["KAL6744135.1","KAL6728359.1","KAL6738750.1","KAL6742890.1","KAL6727795.1","KAL6741112.1","KAL6736959.1","KAL6734660.1","KAL6738698.1","KAL6727272.1","KAL6740392.1","KAL6726657.1"]}