{"hash":"978021797916528445","title":"Retroviral DNA integration and latency","description":"This cluster is dominated by GO terms related to viral integration, recombination, reverse transcription (RNA-templated DNA biosynthesis), DNA replication, and establishment of integrated proviral latency, all characteristic of retroviral lifecycles. Additional terms about viral entry into the host nucleus and host apoptotic activation reflect virus\u2013host interactions, while negative regulation of siRNA processing suggests viral counter-defense mechanisms. Together, they point to retroviral genome integration and latency as the core theme.","confidence":"High","size":22,"edges":231,"triangles":1540,"max_degree":21,"top_function":"DNA recombination","members":[{"accession":"KAL5248573.1","go_terms":["GO:0046718","GO:0006310","GO:0006278","GO:0075713","GO:0075732","GO:0015074","GO:0006260","GO:0039651","GO:1903704"]},{"accession":"KAL5251780.1","go_terms":["GO:0046718","GO:0006310","GO:0006278","GO:0075713","GO:0075732","GO:0015074","GO:0006260","GO:0039651","GO:1903704"]},{"accession":"KAL5255262.1","go_terms":["GO:0046718","GO:0006310","GO:0006278","GO:0075713","GO:0075732","GO:0015074","GO:0006260","GO:0039651","GO:1903704"]},{"accession":"KAL5255344.1","go_terms":["GO:0046718","GO:0006310","GO:0006278","GO:0075713","GO:0075732","GO:0015074","GO:0006260","GO:0039651","GO:1903704"]},{"accession":"KAL5257677.1","go_terms":["GO:0046718","GO:0006310","GO:0006278","GO:0075713","GO:0075732","GO:0015074","GO:0006260","GO:0039651","GO:1903704"]},{"accession":"KAL5258362.1","go_terms":["GO:0090502","GO:0046718","GO:0006278","GO:0015074","GO:0075713","GO:0075732","GO:0043137","GO:0006310","GO:0039651","GO:0006260","GO:1903704"]},{"accession":"KAL5259550.1","go_terms":["GO:0046718","GO:0006310","GO:0006278","GO:0075713","GO:0075732","GO:0015074","GO:0006260","GO:0039651","GO:1903704"]},{"accession":"KAL5260776.1","go_terms":["GO:0046718","GO:0006310","GO:0006278","GO:0075713","GO:0075732","GO:0015074","GO:0006260","GO:0039651","GO:1903704"]},{"accession":"KAL5261854.1","go_terms":["GO:0046718","GO:0006310","GO:0006278","GO:0075713","GO:0075732","GO:0015074","GO:0006260","GO:0039651","GO:1903704"]},{"accession":"KAL5262104.1","go_terms":["GO:0046718","GO:0006310","GO:0006278","GO:0075713","GO:0075732","GO:0015074","GO:0006260","GO:0039651","GO:1903704"]},{"accession":"KAL5263528.1","go_terms":["GO:0046718","GO:0006310","GO:0006278","GO:0075713","GO:0075732","GO:0015074","GO:0006260","GO:0039651","GO:1903704"]},{"accession":"KAL5263535.1","go_terms":["GO:0046718","GO:0006310","GO:0006278","GO:0075713","GO:0075732","GO:0015074","GO:0006260","GO:0039651","GO:1903704"]},{"accession":"KAL5263566.1","go_terms":["GO:0046718","GO:0006310","GO:0006278","GO:0075713","GO:0075732","GO:0015074","GO:0006260","GO:0039651","GO:1903704"]},{"accession":"KAL5266371.1","go_terms":["GO:0046718","GO:0006310","GO:0006278","GO:0075713","GO:0075732","GO:0015074","GO:0006260","GO:0039651","GO:1903704"]},{"accession":"KAL5266984.1","go_terms":["GO:0046718","GO:0006310","GO:0006278","GO:0075713","GO:0075732","GO:0015074","GO:0006260","GO:0039651","GO:1903704"]},{"accession":"KAL5270097.1","go_terms":["GO:0046718","GO:0006310","GO:0006278","GO:0075713","GO:0075732","GO:0015074","GO:0006260","GO:0039651","GO:1903704"]},{"accession":"KAL5270126.1","go_terms":["GO:0046718","GO:0006310","GO:0006278","GO:0075713","GO:0075732","GO:0015074","GO:0006260","GO:0039651","GO:1903704"]},{"accession":"KAL5270679.1","go_terms":["GO:0046718","GO:0006310","GO:0006278","GO:0075713","GO:0075732","GO:0015074","GO:0006260","GO:0039651","GO:1903704"]},{"accession":"KAL5270878.1","go_terms":["GO:0046718","GO:0006310","GO:0006278","GO:0075713","GO:0075732","GO:0015074","GO:0006260","GO:0039651","GO:1903704"]},{"accession":"KAL5271386.1","go_terms":["GO:0046718","GO:0006310","GO:0006278","GO:0075713","GO:0075732","GO:0015074","GO:0006260","GO:0039651","GO:1903704"]},{"accession":"KAL5271404.1","go_terms":["GO:0046718","GO:0006310","GO:0006278","GO:0075713","GO:0075732","GO:0015074","GO:0006260","GO:0039651","GO:1903704"]},{"accession":"KAL5271820.1","go_terms":["GO:0046718","GO:0006310","GO:0006278","GO:0075713","GO:0075732","GO:0015074","GO:0006260","GO:0039651","GO:1903704"]}],"graph":[["KAL5271386.1","KAL5248573.1",0.842],["KAL5271386.1","KAL5251780.1",0.901],["KAL5271386.1","KAL5255262.1",0.823],["KAL5271386.1","KAL5255344.1",0.79],["KAL5271386.1","KAL5257677.1",0.849],["KAL5271386.1","KAL5258362.1",0.788],["KAL5271386.1","KAL5259550.1",0.879],["KAL5271386.1","KAL5260776.1",0.864],["KAL5271386.1","KAL5261854.1",0.855],["KAL5271386.1","KAL5262104.1",0.792],["KAL5271386.1","KAL5263528.1",0.822],["KAL5271386.1","KAL5263535.1",0.849],["KAL5271386.1","KAL5263566.1",0.834],["KAL5271386.1","KAL5266371.1",0.769],["KAL5271386.1","KAL5266984.1",0.788],["KAL5271386.1","KAL5270097.1",0.808],["KAL5271386.1","KAL5270126.1",0.831],["KAL5271386.1","KAL5270679.1",0.826],["KAL5271386.1","KAL5270878.1",0.867],["KAL5271386.1","KAL5271404.1",0.89],["KAL5271386.1","KAL5271820.1",0.834],["KAL5255344.1","KAL5248573.1",0.802],["KAL5255344.1","KAL5251780.1",0.858],["KAL5255344.1","KAL5255262.1",0.797],["KAL5255344.1","KAL5257677.1",0.764],["KAL5255344.1","KAL5258362.1",0.854],["KAL5255344.1","KAL5259550.1",0.869],["KAL5255344.1","KAL5260776.1",0.877],["KAL5255344.1","KAL5261854.1",0.895],["KAL5255344.1","KAL5262104.1",0.841],["KAL5255344.1","KAL5263528.1",0.872],["KAL5255344.1","KAL5263535.1",0.858],["KAL5255344.1","KAL5263566.1",0.861],["KAL5255344.1","KAL5266371.1",0.878],["KAL5255344.1","KAL5266984.1",0.871],["KAL5255344.1","KAL5270097.1",0.889],["KAL5255344.1","KAL5270126.1",0.819],["KAL5255344.1","KAL5270679.1",0.887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