{"hash":"388407915435581446","title":"Steroid, Prostaglandin, and Retinoid Metabolism","description":"This cluster is driven by biosynthetic and metabolic processes for lipid-derived signaling molecules: prostaglandins, androgens/testosterone, and retinoids (retinol/retinal). The presence of PI3K/AKT signaling regulation and smooth muscle proliferation terms suggests related hormonal or signaling roles, tying these metabolism pathways together. A few terms like fructose biosynthesis appear as noise, but the core theme remains steroid, prostaglandin, and retinoid metabolism.","confidence":"Medium","size":23,"edges":241,"triangles":1535,"max_degree":22,"top_function":null,"members":[{"accession":"KAL1510349.1","go_terms":["GO:0035229","GO:0044598","GO:0071799","GO:0001894","GO:0009414","GO:0060135","GO:0042572","GO:0042574","GO:0006750","GO:0019853","GO:0071395","GO:0044597","GO:0071805","GO:0042840","GO:0003091","GO:0042843","GO:0042448","GO:0031098","GO:0043066","GO:0042821","GO:0061370","GO:0051897","GO:0006700","GO:0006707","GO:0046427","GO:0018931","GO:0048661","GO:0007586","GO:0070301","GO:0046370","GO:2000353","GO:0001516","GO:0042415","GO:0019568","GO:0016488","GO:0048385","GO:0070485","GO:0072001","GO:0008584","GO:0072061","GO:0055114","GO:0097238","GO:0071277","GO:0097066","GO:1900053","GO:0030573","GO:0035809","GO:1901653","GO:0006061","GO:0006699","GO:2000224","GO:0071276","GO:0008209"]},{"accession":"KAL1511939.1","go_terms":["GO:0035229","GO:0044598","GO:0071799","GO:0001894","GO:0009414","GO:0060135","GO:0042572","GO:0042574","GO:0006750","GO:0019853","GO:0071395","GO:0044597","GO:0071805","GO:0042840","GO:0003091","GO:0042843","GO:0042448","GO:0031098","GO:0043066","GO:0042821","GO:0061370","GO:0051897","GO:0006700","GO:0006707","GO:0046427","GO:0018931","GO:0048661","GO:0007586","GO:0070301","GO:0046370","GO:2000353","GO:0001516","GO:0042415","GO:0019568","GO:0016488","GO:0048385","GO:0070485","GO:0072001","GO:0008584","GO:0072061","GO:0055114","GO:0097238","GO:0071277","GO:0097066","GO:1900053","GO:0030573","GO:0035809","GO:1901653","GO:0006061","GO:0006699","GO:2000224","GO:0071276","GO:0008209"]},{"accession":"KAL1524736.1","go_terms":["GO:0035229","GO:0044598","GO:0071799","GO:0001894","GO:0009414","GO:0060135","GO:0042572","GO:0042574","GO:0006750","GO:0019853","GO:0071395","GO:0044597","GO:0071805","GO:0042840","GO:0003091","GO:0042843","GO:0042448","GO:0031098","GO:0043066","GO:0042821","GO:0061370","GO:0051897","GO:0006700","GO:0006707","GO:0046427","GO:0018931","GO:0048661","GO:0007586","GO:0070301","GO:0046370","GO:2000353","GO:0001516","GO:0042415","GO:0019568","GO:0016488","GO:0048385","GO:0070485","GO:0072001","GO:0008584","GO:0072061","GO:0055114","GO:0097238","GO:0071277","GO:0097066","GO:1900053","GO:0030573","GO:0035809","GO:1901653","GO:0006061","GO:0006699","GO:2000224","GO:0071276","GO:0008209"]},{"accession":"KAL1525814.1","go_terms":["GO:0000105"]},{"accession":"KAL1528214.1","go_terms":["GO:0043050","GO:0018996","GO:0035229","GO:0044598","GO:0071799","GO:0001894","GO:0009414","GO:0060135","GO:0042572","GO:0042574","GO:0006750","GO:0019853","GO:0071395","GO:0044597","GO:0071805","GO:0042840","GO:0003091","GO:0042843","GO:0042448","GO:0031098","GO:0043066","GO:0042821","GO:0061370","GO:0051897","GO:0006700","GO:0006707","GO:0046427","GO:0018931","GO:0048661","GO:0007586","GO:0070301","GO:0046370","GO:2000353","GO:0001516","GO:0042415","GO:0019568","GO:0016488","GO:0048385","GO:0070485","GO:0072001","GO:0008584","GO:0072061","GO:0055114","GO:0097238","GO:0071277","GO:0097066","GO:1900053","GO:0030573","GO:0035809","GO:1901653","GO:0006061","GO:0006699","GO:2000224","GO:0071276","GO:0008209"]},{"accession":"KAL1528314.1","go_terms":["GO:0017000"]},{"accession":"KAL1529133.1","go_terms":["GO:0006693","GO:0097327","GO:0055114","GO:0006633","GO:0051160","GO:0003016","GO:0032496","GO:0042573","GO:0042572","GO:0009809","GO:0033859","GO:0000947","GO:0006116","GO:0046688","GO:0006062","GO:1900116","GO:0018119","GO:0046370","GO:0051409","GO:0019518","GO:0045777","GO:0043458","GO:0046294","GO:1901159","GO:0010430","GO:0006068","GO:0006069"]},{"accession":"KAL1522332.1","go_terms":["GO:0019595","GO:0051160","GO:0003016","GO:0042572","GO:0032496","GO:0042573","GO:0009809","GO:0033859","GO:0000947","GO:0006116","GO:0046688","GO:1900116","GO:0033498","GO:0018119","GO:0046370","GO:0051409","GO:0019518","GO:0045777","GO:0043458","GO:0046294","GO:1901159","GO:0006062","GO:0010430","GO:0006068","GO:0006069","GO:0006633","GO:0006693","GO:0097327","GO:0071268","GO:0006730","GO:0042745","GO:0019510","GO:0001666","GO:1903758","GO:0002439","GO:0006564","GO:0033353","GO:0009099","GO:0009097","GO:0007584","GO:0030435","GO:0006189","GO:0008615","GO:0055114","GO:0042183","GO:0042853","GO:0046392","GO:0009854"]},{"accession":"KAL1507991.1","go_terms":["GO:0035229","GO:0044598","GO:0071799","GO:0001894","GO:0009414","GO:0060135","GO:0042572","GO:0042574","GO:0006750","GO:0019853","GO:0071395","GO:0044597","GO:0071805","GO:0042840","GO:0003091","GO:0042843","GO:0042448","GO:0031098","GO:0043066","GO:0042821","GO:0061370","GO:0051897","GO:0006700","GO:0006707","GO:0046427","GO:0018931","GO:0048661","GO:0007586","GO:0070301","GO:0046370","GO:2000353","GO:0001516","GO:0042415","GO:0019568","GO:0016488","GO:0048385","GO:0070485","GO:0072001","GO:0008584","GO:0072061","GO:0055114","GO:0097238","GO:0071277","GO:0097066","GO:1900053","GO:0030573","GO:0035809","GO:1901653","GO:0006061","GO:0006699","GO:2000224","GO:0071276","GO:0008209"]},{"accession":"KAL1515016.1","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