{"hash":"165592582014093702","title":"Epidermal sphingolipid metabolism and keratinocyte differentiation","description":"The terms point to sphingolipid biosynthesis (sphingosine, phytosphingosine) and ceramide catabolism, plus keratinocyte differentiation and adhesion regulation. This suggests a cohesive theme around epidermal lipid metabolism and keratinocyte maturation, with supporting signals from calcium response and xenobiotic/pH responses common in skin biology.","confidence":"Medium","size":18,"edges":0,"triangles":0,"max_degree":0,"top_function":null,"members":[{"accession":"KAL1510983.1","go_terms":[]},{"accession":"KAL1511327.1","go_terms":["GO:0090285","GO:0030216","GO:0010446","GO:0001953","GO:0071277","GO:0033629","GO:0035690","GO:0046514","GO:0046512","GO:0071602"]},{"accession":"KAL1518451.1","go_terms":[]},{"accession":"KAL1519394.1","go_terms":[]},{"accession":"KAL1519565.1","go_terms":[]},{"accession":"KAL1519713.1","go_terms":[]},{"accession":"KAL1524552.1","go_terms":[]},{"accession":"KAL1530653.1","go_terms":["GO:0006067","GO:0061668"]},{"accession":"KAL1529955.1","go_terms":[]},{"accession":"KAL1528184.1","go_terms":[]},{"accession":"KAL1527593.1","go_terms":["GO:0003231","GO:1903779"]},{"accession":"KAL1527749.1","go_terms":[]},{"accession":"KAL1525723.1","go_terms":[]},{"accession":"KAL1496079.1","go_terms":[]},{"accession":"KAL1500117.1","go_terms":[]},{"accession":"KAL1500708.1","go_terms":[]},{"accession":"KAL1503287.1","go_terms":[]},{"accession":"KAL1503420.1","go_terms":[]}],"graph":[],"all_go_terms":{"GO:0090285":1,"GO:0046512":1,"GO:0046514":1,"GO:0001953":1,"GO:0071277":1,"GO:0035690":1,"GO:0071602":1,"GO:0033629":1,"GO:0030216":1,"GO:0010446":1,"GO:0006067":1,"GO:0061668":1,"GO:0003231":1,"GO:1903779":1},"recipe_readded":["KAL1526030.1"]}