{"hash":"741148004972854933","title":"ER Stress and Redox-Regulated Transcription","description":"The top terms cluster around protein folding in the endoplasmic reticulum and redox homeostasis, pointing to ER/oxidative stress handling. The presence of transcription-related terms (DNA-templated transcription and negative regulation of RNA Pol II) suggests these proteins also participate in linking ER redox status and stress signals to transcriptional regulation. This combination supports a theme of ER-associated stress responses modulating transcription.","confidence":"Medium","size":14,"edges":12,"triangles":3,"max_degree":8,"top_function":null,"members":[{"accession":"KAJ9469985.1","go_terms":[]},{"accession":"KAJ9443921.1","go_terms":[]},{"accession":"KAJ9435705.1","go_terms":[]},{"accession":"KAJ9463325.1","go_terms":["GO:0033158","GO:0043388","GO:0045454","GO:0000122","GO:0098869","GO:1903206","GO:0006662","GO:0080058","GO:0034599","GO:0018401","GO:0055114","GO:0046826","GO:0006351","GO:0016032","GO:1903026","GO:0034976","GO:0034975","GO:0030091","GO:0017004","GO:0072358","GO:0045494","GO:0010196"]},{"accession":"KAJ9454590.1","go_terms":["GO:0019876","GO:0046677","GO:0030655","GO:0033252"]},{"accession":"KAJ9448544.1","go_terms":["GO:0006452","GO:0090084","GO:0006458","GO:0031204","GO:0006986","GO:0071374","GO:0001707","GO:0070843","GO:1901621","GO:0006260","GO:0070389","GO:0097428","GO:0006469","GO:0032781","GO:0006626","GO:0030433","GO:0009408","GO:0045454","GO:0036494","GO:0051259","GO:1900035","GO:0046825","GO:0035719","GO:0071630","GO:0034975"]},{"accession":"KAJ9452872.1","go_terms":[]},{"accession":"KAJ9449937.1","go_terms":[]},{"accession":"KAJ9444088.1","go_terms":[]},{"accession":"KAJ9461403.1","go_terms":["GO:0060325"]},{"accession":"KAJ9461695.1","go_terms":[]},{"accession":"KAJ9469570.1","go_terms":[]},{"accession":"KAJ9439923.1","go_terms":[]},{"accession":"KAJ9442158.1","go_terms":[]}],"graph":[["KAJ9444088.1","KAJ9439923.1",0.711],["KAJ9444088.1","KAJ9448544.1",0.556],["KAJ9444088.1","KAJ9452872.1",0.631],["KAJ9449937.1","KAJ9454590.1",0.595],["KAJ9461403.1","KAJ9452872.1",0.612],["KAJ9448544.1","KAJ9452872.1",0.886],["KAJ9469570.1","KAJ9452872.1",0.576],["KAJ9452872.1","KAJ9461695.1",0.619],["KAJ9452872.1","KAJ9439923.1",0.771],["KAJ9452872.1","KAJ9442158.1",0.549],["KAJ9452872.1","KAJ9454590.1",0.516],["KAJ9461695.1","KAJ9454590.1",0.621]],"all_go_terms":{"GO:0006351":1,"GO:0000122":1,"GO:1903206":1,"GO:0055114":1,"GO:0072358":1,"GO:0080058":1,"GO:0006662":1,"GO:1903026":1,"GO:0046826":1,"GO:0098869":1,"GO:0034976":1,"GO:0017004":1,"GO:0018401":1,"GO:0030091":1,"GO:0034599":1,"GO:0045494":1,"GO:0010196":1,"GO:0043388":1,"GO:0034975":2,"GO:0045454":2,"GO:0033158":1,"GO:0016032":1,"GO:0030655":1,"GO:0046677":1,"GO:0033252":1,"GO:0019876":1,"GO:0006260":1,"GO:0097428":1,"GO:0032781":1,"GO:0001707":1,"GO:0006469":1,"GO:0030433":1,"GO:1901621":1,"GO:0071630":1,"GO:0070843":1,"GO:0006626":1,"GO:0051259":1,"GO:0090084":1,"GO:0006452":1,"GO:0036494":1,"GO:1900035":1,"GO:0006986":1,"GO:0006458":1,"GO:0070389":1,"GO:0046825":1,"GO:0071374":1,"GO:0035719":1,"GO:0031204":1,"GO:0009408":1,"GO:0060325":1},"recipe_readded":["KAJ9473435.1","KAJ9458115.1","KAJ9449574.1","KAJ9437155.1","KAJ9446152.1","KAJ9450761.1","KAJ9461902.1","KAJ9439224.1","KAJ9468260.1","KAJ9462961.1","KAJ9471771.1","KAJ9469321.1","KAJ9435596.1","KAJ9459266.1","KAJ9446329.1","KAJ9449646.1","KAJ9447403.1","KAJ9446703.1","KAJ9440692.1","KAJ9451395.1"]}