{"hash":"733484827501557197","title":"Mitochondrial metabolism and innate immune signaling","description":"The top GO terms point to mitochondria-driven energy and protein handling (mitochondrial protein processing; proton motive force\u2013driven ATP synthesis; stress-induced mitochondrial fusion) alongside immune-related processes (interleukin-2 production; positive regulation of TLR3 signaling). Lipid localization and SREBP signaling extend the theme to membrane/lipid metabolism that interfaces with mitochondrial function. Taken together, the proteins appear to cluster around mitochondrial energy metabolism with coordinated innate immune signaling and lipid/membrane dynamics.","confidence":"Medium","size":3,"edges":2,"triangles":0,"max_degree":2,"top_function":null,"members":[{"accession":"KAJ9457449.1","go_terms":["GO:0032623","GO:1903044","GO:1901585","GO:0007007","GO:1903905","GO:0000001","GO:0072249","GO:0032226","GO:0022617","GO:0045541","GO:0070584","GO:0032933","GO:0060355","GO:0007588","GO:0052547","GO:1990046","GO:0034141","GO:0030433","GO:0010876","GO:0010918","GO:0090297","GO:0001302","GO:2000049","GO:1900210","GO:0070528","GO:0045861","GO:0050852","GO:0006851","GO:0034982","GO:0042776","GO:0035710"]},{"accession":"KAJ9457525.1","go_terms":["GO:2000324","GO:0015979","GO:0000413","GO:0006986","GO:0009736","GO:0070979","GO:0051348","GO:0035955","GO:0030850","GO:0016576","GO:1903646","GO:1902325","GO:1903070","GO:0010288","GO:0006463","GO:0070301","GO:0051291","GO:2000531","GO:0071276","GO:0043278","GO:1903071","GO:1901215","GO:0046661","GO:0090526","GO:0031400","GO:0009938","GO:0007091"]},{"accession":"KAJ9451192.1","go_terms":["GO:0055059","GO:0006470","GO:2001034","GO:0072462","GO:1904290","GO:1902660","GO:0045722"]}],"graph":[["KAJ9451192.1","KAJ9457449.1",0.563],["KAJ9457449.1","KAJ9457525.1",0.574]],"all_go_terms":{"GO:0032623":1,"GO:0034982":1,"GO:0042776":1,"GO:0045861":1,"GO:0034141":1,"GO:1990046":1,"GO:0030433":1,"GO:0001302":1,"GO:0032933":1,"GO:0010876":1,"GO:0072249":1,"GO:0007588":1,"GO:2000049":1,"GO:0050852":1,"GO:0070584":1,"GO:0052547":1,"GO:1903905":1,"GO:1901585":1,"GO:0000001":1,"GO:0022617":1,"GO:1900210":1,"GO:0070528":1,"GO:0035710":1,"GO:0032226":1,"GO:0007007":1,"GO:0090297":1,"GO:0010918":1,"GO:0045541":1,"GO:1903044":1,"GO:0060355":1,"GO:0006851":1,"GO:2000324":1,"GO:1903071":1,"GO:0030850":1,"GO:1903070":1,"GO:0046661":1,"GO:0070301":1,"GO:0043278":1,"GO:0051348":1,"GO:0007091":1,"GO:0016576":1,"GO:0035955":1,"GO:1903646":1,"GO:0071276":1,"GO:1902325":1,"GO:2000531":1,"GO:0009938":1,"GO:0009736":1,"GO:0006986":1,"GO:0000413":1,"GO:0010288":1,"GO:0070979":1,"GO:0090526":1,"GO:1901215":1,"GO:0051291":1,"GO:0031400":1,"GO:0015979":1,"GO:0006463":1,"GO:0045722":1,"GO:2001034":1,"GO:0072462":1,"GO:0006470":1,"GO:0055059":1,"GO:1904290":1,"GO:1902660":1},"recipe_readded":[]}