{"hash":"2059816747566823769","title":"Proteostasis and Protein Degradation","description":"The GO terms cluster around protein quality control and degradation pathways, notably nuclear protein quality control by the ubiquitin-proteasome system, misfolded protein transport, and ubiquitin-dependent ERAD. These strongly point to roles in protein homeostasis and turnover, with other terms appearing incidental. Thus, the cluster is best described as a proteostasis/degradation module.","confidence":"Medium","size":10,"edges":3,"triangles":0,"max_degree":3,"top_function":null,"members":[{"accession":"KAJ9470813.1","go_terms":[]},{"accession":"KAJ9444668.1","go_terms":[]},{"accession":"KAJ9457023.1","go_terms":[]},{"accession":"KAJ9472662.1","go_terms":[]},{"accession":"KAJ9458630.1","go_terms":["GO:0006452","GO:0090084","GO:0006458","GO:0031204","GO:0006986","GO:0071374","GO:0001707","GO:0070843","GO:1901621","GO:0006260","GO:0070389","GO:0097428","GO:0006469","GO:0032781","GO:0006626","GO:0030433","GO:0009408","GO:0045454","GO:0036494","GO:0051259","GO:1900035","GO:0046825","GO:0035719","GO:0071630","GO:0034975"]},{"accession":"KAJ9449778.1","go_terms":[]},{"accession":"KAJ9465886.1","go_terms":[]},{"accession":"KAJ9453453.1","go_terms":[]},{"accession":"KAJ9455290.1","go_terms":[]},{"accession":"KAJ9472922.1","go_terms":["GO:0006915","GO:0033081"]}],"graph":[["KAJ9458630.1","KAJ9453453.1",0.558],["KAJ9458630.1","KAJ9465886.1",0.679],["KAJ9458630.1","KAJ9472662.1",0.703]],"all_go_terms":{"GO:0006260":1,"GO:0097428":1,"GO:0032781":1,"GO:0001707":1,"GO:0006469":1,"GO:0030433":1,"GO:1901621":1,"GO:0071630":1,"GO:0070843":1,"GO:0006626":1,"GO:0051259":1,"GO:0090084":1,"GO:0006452":1,"GO:0036494":1,"GO:1900035":1,"GO:0006986":1,"GO:0006458":1,"GO:0070389":1,"GO:0046825":1,"GO:0071374":1,"GO:0034975":1,"GO:0045454":1,"GO:0035719":1,"GO:0031204":1,"GO:0009408":1,"GO:0033081":1,"GO:0006915":1},"recipe_readded":["KAJ9470717.1","KAJ9449390.1","KAJ9457225.1","KAJ9440750.1","KAJ9449007.1","KAJ9447269.1","KAJ9453004.1","KAJ9441587.1","KAJ9449800.1","KAJ9462084.1","KAJ9473185.1","KAJ9471144.1","KAJ9463496.1","KAJ9465306.1","KAJ9464082.1","KAJ9469459.1","KAJ9465765.1","KAJ9438984.1","KAJ9463105.1","KAJ9441326.1"]}