{"hash":"993279751161123295","title":"Proteolysis and ECM remodeling","description":"This cluster is dominated by GO terms describing proteolytic and catabolic processes affecting extracellular components and signaling peptides (e.g., collagen catabolic, bradykinin catabolic, neuropeptide catabolic), plus related regulation of catalytic activity. The presence of development-related remodeling terms (lung morphogenesis, intramembranous ossification) further supports a theme of extracellular matrix remodeling and peptide turnover driven by proteases. Overall, a proteolysis/ECM remodeling theme best captures the shared functions of the proteins in this group.","confidence":"High","size":5,"edges":2,"triangles":0,"max_degree":1,"top_function":null,"members":[{"accession":"KAL0479161.1","go_terms":[]},{"accession":"KAL0482691.1","go_terms":["GO:0007124","GO:0001403","GO:2000010","GO:0033299","GO:0061060","GO:0070863"]},{"accession":"KAL0491499.1","go_terms":["GO:0006452","GO:0090084","GO:0006458","GO:0031204","GO:0006986","GO:0071374","GO:0001707","GO:0070843","GO:1901621","GO:0006260","GO:0070389","GO:0097428","GO:0006469","GO:0032781","GO:0006626","GO:0030433","GO:0009408","GO:0045454","GO:0036494","GO:0051259","GO:1900035","GO:0046825","GO:0035719","GO:0071630","GO:0034975"]},{"accession":"KAL0478578.1","go_terms":["GO:0051603","GO:0050790","GO:0097067","GO:0001957","GO:0010815","GO:0010813","GO:0030574","GO:2000179","GO:0001913","GO:0060441","GO:0034769","GO:0060448","GO:0046697","GO:0045453","GO:0035593"]},{"accession":"KAL0486560.1","go_terms":["GO:0051603","GO:0050790","GO:0097067","GO:0001957","GO:0010815","GO:0010813","GO:0030574","GO:2000179","GO:0001913","GO:0060441","GO:0034769","GO:0060448","GO:0046697","GO:0045453","GO:0035593","GO:2001235","GO:0006508"]}],"graph":[["KAL0479161.1","KAL0482691.1",0.777],["KAL0478578.1","KAL0486560.1",0.565]],"all_go_terms":{"GO:0033299":1,"GO:0070863":1,"GO:0061060":1,"GO:0007124":1,"GO:2000010":1,"GO:0001403":1,"GO:0006469":1,"GO:0045454":1,"GO:0006626":1,"GO:0071630":1,"GO:0036494":1,"GO:1900035":1,"GO:0071374":1,"GO:0031204":1,"GO:0006986":1,"GO:0034975":1,"GO:0032781":1,"GO:1901621":1,"GO:0009408":1,"GO:0035719":1,"GO:0046825":1,"GO:0006260":1,"GO:0001707":1,"GO:0070389":1,"GO:0070843":1,"GO:0051259":1,"GO:0090084":1,"GO:0030433":1,"GO:0006452":1,"GO:0006458":1,"GO:0097428":1,"GO:0030574":2,"GO:2000179":2,"GO:0097067":2,"GO:0050790":2,"GO:0010815":2,"GO:0060441":2,"GO:0010813":2,"GO:0051603":2,"GO:0001957":2,"GO:0001913":2,"GO:0060448":2,"GO:0045453":2,"GO:0035593":2,"GO:0034769":2,"GO:0046697":2,"GO:0006508":1,"GO:2001235":1},"recipe_readded":["KAL0482716.1","KAL0478671.1","KAL0488082.1","KAL0485077.1","KAL0480182.1","KAL0491879.1","KAL0489836.1","KAL0479914.1","KAL0488566.1","KAL0491858.1","KAL0488088.1","KAL0489972.1","KAL0485997.1","KAL0482432.1","KAL0486128.1","KAL0487608.1","KAL0485472.1","KAL0485714.1","KAL0476714.1","KAL0487435.1"]}