{"hash":"2140349900638813705","title":"Ubiquitin-Dependent TNF/NF-\u03baB Signaling","description":"The top GO terms center on ubiquitin-dependent protein catabolic processes and various ubiquitin linkages (K63, K6), coupled with positive regulation of TNF-mediated signaling and I-kappaB phosphorylation. This points to a cohesive function where ubiquitination modulates TNF/NF-\u03baB signaling, with additional hints of chromatin-level regulation via histone ubiquitination. Overall, the cluster seems to represent ubiquitin-mediated control of inflammatory signaling and related chromatin processes.","confidence":"High","size":6,"edges":0,"triangles":0,"max_degree":0,"top_function":null,"members":[{"accession":"KAI9172864.1","go_terms":[]},{"accession":"KAI9175930.1","go_terms":["GO:0038018","GO:0016558","GO:0030433","GO:0060816","GO:0051865","GO:0042787","GO:0046621","GO:1900095","GO:0070936","GO:0033151","GO:0033209","GO:0009048","GO:0036205","GO:0046328","GO:2000620","GO:0042981","GO:0007250","GO:0070512","GO:0085020","GO:0070535","GO:1903265","GO:1903762","GO:1903721","GO:1901253","GO:0090073"]},{"accession":"KAI9184072.1","go_terms":["GO:0060386","GO:0031571","GO:0071406","GO:0031146","GO:1902916","GO:0071276","GO:0030174","GO:0042752","GO:1903378","GO:0042787","GO:0046685","GO:0000083","GO:0000209"]},{"accession":"KAI9184202.1","go_terms":[]},{"accession":"KAI9178833.1","go_terms":["GO:2000185","GO:0035435","GO:0016237","GO:0006814","GO:0042144","GO:0030643","GO:0048016","GO:0016036","GO:0070417","GO:0080040","GO:0046475","GO:0006799"]},{"accession":"KAI9187812.1","go_terms":["GO:0033151","GO:0033209","GO:0009048","GO:0036205","GO:0046328","GO:2000620","GO:0042981","GO:0007250","GO:0070512","GO:0085020","GO:0042787","GO:0070535","GO:1903265","GO:1903762","GO:1903721","GO:1901253","GO:0090073","GO:0051865"]}],"graph":[],"all_go_terms":{"GO:1903265":2,"GO:0033209":2,"GO:1900095":1,"GO:0070535":2,"GO:0085020":2,"GO:0016558":1,"GO:0046621":1,"GO:1903721":2,"GO:0090073":2,"GO:0036205":2,"GO:0009048":2,"GO:0030433":1,"GO:1901253":2,"GO:0042981":2,"GO:0042787":3,"GO:0007250":2,"GO:0060816":1,"GO:0070936":1,"GO:0070512":2,"GO:2000620":2,"GO:0038018":1,"GO:0033151":2,"GO:0046328":2,"GO:1903762":2,"GO:0051865":2,"GO:0071406":1,"GO:0031571":1,"GO:0030174":1,"GO:1903378":1,"GO:0000083":1,"GO:0000209":1,"GO:0042752":1,"GO:0060386":1,"GO:0031146":1,"GO:0046685":1,"GO:1902916":1,"GO:0071276":1,"GO:0080040":1,"GO:0070417":1,"GO:0048016":1,"GO:0016036":1,"GO:0042144":1,"GO:0006799":1,"GO:0006814":1,"GO:0016237":1,"GO:0046475":1,"GO:0035435":1,"GO:2000185":1,"GO:0030643":1},"recipe_readded":["KAI9188762.1","KAI9183399.1","KAI9189876.1","KAI9190205.1","KAI9179269.1","KAI9188384.1","KAI9159351.1","KAI9173018.1","KAI9175780.1","KAI9159241.1","KAI9189393.1","KAI9183337.1","KAI9159592.1","KAI9164271.1","KAI9168591.1","KAI9183295.1","KAI9189319.1","KAI9159339.1","KAI9188670.1","KAI9168350.1"]}