{"hash":"1885684326003125272","title":"Membrane Protein Proteolysis and NFAT Signaling","description":"This cluster is driven by GO terms for membrane protein proteolysis in various contexts (ectodomain, intracellular domain, and ER-to-cytosol retrograde transport) and by positive regulation of the calcineurin-NFAT signaling cascade, plus general immune regulation. The presence of a spliceosome-related term and lithium response appears as noise, but the core theme centers on proteolytic processing of membrane proteins and downstream signaling relevant to immune pathways. ","confidence":"Medium","size":16,"edges":0,"triangles":0,"max_degree":0,"top_function":null,"members":[{"accession":"KAI9151216.1","go_terms":[]},{"accession":"KAI9155867.1","go_terms":[]},{"accession":"KAI9159494.1","go_terms":[]},{"accession":"KAI9176085.1","go_terms":[]},{"accession":"KAI9179072.1","go_terms":[]},{"accession":"KAI9183486.1","go_terms":[]},{"accession":"KAI9183949.1","go_terms":[]},{"accession":"KAI9188735.1","go_terms":[]},{"accession":"KAI9189329.1","go_terms":["GO:0050776","GO:1904211","GO:0051533","GO:0006509","GO:0070886","GO:0031293"]},{"accession":"KAI9189918.1","go_terms":["GO:0010226","GO:0000388"]},{"accession":"KAI9190305.1","go_terms":[]},{"accession":"KAI9187691.1","go_terms":[]},{"accession":"KAI9188413.1","go_terms":[]},{"accession":"KAI9164634.1","go_terms":[]},{"accession":"KAI9168638.1","go_terms":[]},{"accession":"KAI9190294.1","go_terms":[]}],"graph":[],"all_go_terms":{"GO:1904211":1,"GO:0050776":1,"GO:0051533":1,"GO:0070886":1,"GO:0006509":1,"GO:0031293":1,"GO:0010226":1,"GO:0000388":1},"recipe_readded":["KAI9188225.1","KAI9179182.1","KAI9187884.1","KAI9190012.1","KAI9190332.1","KAI9168628.1","KAI9159549.1","KAI9152684.1","KAI9184406.1","KAI9159219.1","KAI9148589.1","KAI9179912.1","KAI9189014.1","KAI9150913.1","KAI9173153.1","KAI9190205.1","KAI9152573.1","KAI9187750.1","KAI9168123.1","KAI9176113.1"]}