{"hash":"2042956121662190291","title":"Neuronal Stress and Ubiquitin Signaling","description":"The terms cluster around neuronal stress responses (heavy metal and oxidative stress, neuronal apoptotic signaling, synapse assembly) and proteostasis via ubiquitination (ubiquitin-dependent catabolic processes and protein polyubiquitination). While there is a broader cell cycle/DNA damage signaling component, the strongest and most cohesive theme ties neuronal stress pathways to ubiquitin-mediated protein regulation, suggesting cells coordinating survival, turnover, and synaptic maintenance under stress.","confidence":"Medium","size":15,"edges":3,"triangles":0,"max_degree":3,"top_function":null,"members":[{"accession":"KAF7759778.1","go_terms":["GO:0060386","GO:0031571","GO:0071406","GO:0031146","GO:1902916","GO:0071276","GO:0030174","GO:0042752","GO:1903378","GO:0042787","GO:0046685","GO:0000083","GO:0000209"]},{"accession":"KAF7760742.1","go_terms":[]},{"accession":"KAF7760893.1","go_terms":["GO:0008285","GO:0070544","GO:0031146","GO:0046785","GO:0006516","GO:0007057","GO:0021678","GO:0021993","GO:0051436","GO:0001556","GO:0060386","GO:0031571","GO:0071406","GO:1902916","GO:0071276","GO:0030174","GO:0042752","GO:1903378","GO:0042787","GO:0046685","GO:0000083","GO:0000209"]},{"accession":"KAF7761343.1","go_terms":[]},{"accession":"KAF7768026.1","go_terms":[]},{"accession":"KAF7768033.1","go_terms":["GO:0060386","GO:0031571","GO:0071406","GO:0031146","GO:1902916","GO:0071276","GO:0030174","GO:0042752","GO:1903378","GO:0042787","GO:0046685","GO:0000083","GO:0000209"]},{"accession":"KAF7768152.1","go_terms":["GO:0060386","GO:0031571","GO:0071406","GO:0031146","GO:1902916","GO:0071276","GO:0030174","GO:0042752","GO:1903378","GO:0042787","GO:0046685","GO:0000083","GO:0000209"]},{"accession":"KAF7768418.1","go_terms":[]},{"accession":"KAF7770709.1","go_terms":[]},{"accession":"KAF7770743.1","go_terms":[]},{"accession":"KAF7770826.1","go_terms":["GO:0060386","GO:0031571","GO:0071406","GO:0031146","GO:1902916","GO:0071276","GO:0030174","GO:0042752","GO:1903378","GO:0042787","GO:0046685","GO:0000083","GO:0000209"]},{"accession":"KAF7771115.1","go_terms":[]},{"accession":"KAF7778513.1","go_terms":[]},{"accession":"KAF7782200.1","go_terms":[]},{"accession":"KAF7784687.1","go_terms":["GO:0060386","GO:0031571","GO:0071406","GO:0031146","GO:1902916","GO:0071276","GO:0030174","GO:0042752","GO:1903378","GO:0042787","GO:0046685","GO:0000083","GO:0000209"]}],"graph":[["KAF7768418.1","KAF7759778.1",0.787],["KAF7760893.1","KAF7759778.1",0.853],["KAF7759778.1","KAF7770709.1",0.539]],"all_go_terms":{"GO:0031571":6,"GO:0042787":6,"GO:0060386":6,"GO:1903378":6,"GO:0000083":6,"GO:0071406":6,"GO:1902916":6,"GO:0071276":6,"GO:0042752":6,"GO:0000209":6,"GO:0046685":6,"GO:0030174":6,"GO:0031146":6,"GO:0021678":1,"GO:0051436":1,"GO:0021993":1,"GO:0008285":1,"GO:0006516":1,"GO:0001556":1,"GO:0007057":1,"GO:0070544":1,"GO:0046785":1},"recipe_readded":["KAF7773578.1","KAF7762654.1","KAF7767953.1","KAF7771120.1","KAF7762195.1","KAF7782836.1","KAF7775690.1","KAF7783876.1","KAF7773134.1","KAF7770750.1","KAF7778768.1","KAF7776173.1","KAF7785025.1","KAF7760413.1","KAF7776288.1","KAF7759792.1","KAF7770724.1","KAF7763664.1","KAF7784094.1","KAF7771716.1"]}