{"hash":"283742506947699734","title":"Redox Homeostasis and Oxidative Stress Signaling","description":"The top GO terms cluster around redox balance and detoxification of reactive oxygen species (cell redox homeostasis, hydrogen peroxide and superoxide removal, cellular response to hydrogen peroxide), with supporting signals in ROS-responsive pathways (I-kappaB phosphorylation, non-canonical NF-kappaB and stress-activated MAPK regulation). Copper transport also ties to metal-associated redox biology. While erythrocyte homeostasis and spermatogenesis are present, the dominant theme is redox regulation and oxidative stress signaling.","confidence":"High","size":5,"edges":1,"triangles":0,"max_degree":1,"top_function":null,"members":[{"accession":"KAI5064232.1","go_terms":[]},{"accession":"KAI5069454.1","go_terms":[]},{"accession":"KAI5074328.1","go_terms":[]},{"accession":"KAI5057128.1","go_terms":["GO:0006878","GO:0008535","GO:0006825","GO:0007308","GO:0045454","GO:0017004","GO:0008584","GO:0042744","GO:0007252","GO:0034101","GO:0018171","GO:0070301","GO:2000255","GO:0032872","GO:0007283","GO:0030416","GO:0042345","GO:0042267","GO:0019471","GO:0022417","GO:0019430","GO:0030198"]},{"accession":"KAI5067986.1","go_terms":["GO:0006950"]}],"graph":[["KAI5067986.1","KAI5069454.1",0.751]],"all_go_terms":{"GO:0006825":1,"GO:0042744":1,"GO:0045454":1,"GO:0019430":1,"GO:0042345":1,"GO:0034101":1,"GO:0007252":1,"GO:0070301":1,"GO:0032872":1,"GO:0007283":1,"GO:0022417":1,"GO:0006878":1,"GO:0019471":1,"GO:0008535":1,"GO:0030416":1,"GO:0008584":1,"GO:0030198":1,"GO:0042267":1,"GO:0007308":1,"GO:0017004":1,"GO:2000255":1,"GO:0018171":1,"GO:0006950":1},"recipe_readded":["KAI5072183.1","KAI5072847.1","KAI5071565.1","KAI5077871.1","KAI5054947.1","KAI5067080.1","KAI5062018.1","KAI5077295.1","KAI5077665.1","KAI5082759.1","KAI5055783.1","KAI5057655.1","KAI5078303.1","KAI5071941.1","KAI5084000.1","KAI5077496.1","KAI5064619.1","KAI5061901.1","KAI5081759.1","KAI5082189.1"]}