{"hash":"243087277931846264","title":"Amino acid catabolism fueling central carbon metabolism","description":"This small cluster centers on core energy metabolism: leucine and other amino acid catabolism feeding into central carbon pathways such as the TCA cycle, 2-oxoglutarate metabolism, glycolysis, and gluconeogenesis. The GO terms collectively point to management of carbon flux and energy production, with malonyl-CoA biosynthesis linking to broader metabolic context. Despite the single reported edge, the dominant theme is cohesive central carbon metabolism driven by amino acid catabolism.","confidence":"High","size":3,"edges":1,"triangles":0,"max_degree":1,"top_function":null,"members":[{"accession":"KAI5063362.1","go_terms":["GO:0043617","GO:0006086","GO:0033512","GO:0006213","GO:0006099","GO:0006096","GO:0000002","GO:0006103","GO:0006814","GO:2001295","GO:0042759","GO:0006552","GO:0006094"]},{"accession":"KAI5076427.1","go_terms":["GO:0006085","GO:0019679","GO:0019629","GO:0006099"]},{"accession":"KAI5072403.1","go_terms":["GO:0006633","GO:0009234","GO:0019654","GO:0015911","GO:0009437","GO:0001676","GO:0019290","GO:0008206","GO:0008218","GO:0009698","GO:0010030","GO:0010214","GO:0090410","GO:0001579","GO:0036112","GO:0019629","GO:0044539","GO:0070395","GO:0019427","GO:1902987","GO:0010124","GO:0000038","GO:0043041","GO:0019542"]}],"graph":[["KAI5063362.1","KAI5076427.1",0.976]],"all_go_terms":{"GO:0006103":1,"GO:0006099":2,"GO:0006814":1,"GO:0006552":1,"GO:0006096":1,"GO:0043617":1,"GO:0006094":1,"GO:0000002":1,"GO:2001295":1,"GO:0006086":1,"GO:0033512":1,"GO:0042759":1,"GO:0006213":1,"GO:0006085":1,"GO:0019629":2,"GO:0019679":1,"GO:0019427":1,"GO:0008218":1,"GO:0090410":1,"GO:0009437":1,"GO:0008206":1,"GO:0036112":1,"GO:0010214":1,"GO:0019654":1,"GO:0009698":1,"GO:0010030":1,"GO:0001676":1,"GO:0009234":1,"GO:0019542":1,"GO:0043041":1,"GO:0044539":1,"GO:0001579":1,"GO:1902987":1,"GO:0070395":1,"GO:0015911":1,"GO:0000038":1,"GO:0019290":1,"GO:0010124":1,"GO:0006633":1},"recipe_readded":["KAI5084523.1","KAI5080056.1","KAI5069656.1","KAI5077289.1","KAI5078421.1","KAI5065030.1","KAI5062147.1","KAI5075091.1","KAI5059473.1","KAI5055156.1","KAI5077019.1","KAI5056682.1","KAI5072715.1","KAI5061355.1","KAI5055686.1","KAI5063126.1","KAI5062768.1","KAI5073178.1","KAI5059916.1","KAI5064227.1"]}