{"hash":"1300308749395209430","title":"One-carbon metabolism and nucleotide biosynthesis","description":"The top GO terms cluster around serine/glycine metabolism and folate-related reactions (L-serine biosynthesis/catabolism, tetrahydrofolate response) that feed one-carbon units into nucleotide synthesis pathways (dTMP and purine biosynthesis) and methylation processes. This points to a cohesive theme of folate-dependent one-carbon metabolism powering nucleotide production and related methylation, with ancillary signals related to translation regulation and interferon response reflecting broader cellular 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