((dhfr-sup:B, dhfr-sup:A), (dhfr-sup:D, dhfr-sup:C))
Core Residues: 130
Core RMSD: 0.643
Raw Score: 225.375
Reference structure: dhfr-sup:B

dhfr-sup:A   ----LNCIVAVSQNMGIGK---NGDLPW-PPLRNEFRYFQRMTTTSSVEGKQ--------    47 
dhfr-sup:B   VRS-LNSIVAVCQNMGIG-K--DGNLP-WPPLRNEYKYFQRMTS--------TSHVEGKQ    47 
dhfr-sup:C   ---MISLIAALAVDRVIG--M-ENAMP--WNLPADLAWFKRNTL----------------    36 
dhfr-sup:D   ----TAFLWAQNRNGLIG---KDGHLP--WHLPDDLHYFRAQTV----------------    35 

dhfr-sup:A   --NLVIMGKKTWFSIPEKNR-------------PLKGRINLVLSR--ELKEPPQGA----    86 
dhfr-sup:B   --NAVIMGKKTWFS------IPEKNR-------PLKDRINIVLS-R-ELKEA----PKGA    86 
dhfr-sup:C   D-KPVIMGRHTWES------------IGR----PLPGRKNIILS---SQPGT--------    68 
dhfr-sup:D   -GKIMVVGRRTYES---------------FPKRPLPERTNVVLT--HQEDYQ--------    69 

dhfr-sup:A   ------HFLSRSLDDALKLTEQPELANKVD-----------------MVWIVGGSSVYKE   123 
dhfr-sup:B   ------HYLSKSLDDALALLD---------SPELKSKVD--------MVWIVGGTAVYKA   123 
dhfr-sup:C   DDR---VTWVKSVDEAIAACG------------------DVP-----EIMVIGGGRVYEQ   102 
dhfr-sup:D   ---AQGAVVVHDVAAVFAYAK---------------------QHLDQELVIAGGAQIFTA   105 

dhfr-sup:A   AMNHPGH-----------LKLFVTRIMQDFESDTFFPEIDLE---KYKLLPEYPGVLSDV   169 
dhfr-sup:B   AM-----EKPIN------HRLFVTRILHEFESDTFFPEIDY-K--DFKLL----------   159 
dhfr-sup:C   FL----------PKA---QKLYLTHIDAEVEGDTHFPDYEP--D-DWESV----------   136 
dhfr-sup:D   FK-------------DDVDTLLVTRLAGSFEGDTKMIPLNW---DDFTKV----------   139 

dhfr-sup:A   QEEKG--------------------------------------IKYKFEVYEKN-----   185 
dhfr-sup:B   -----TEYPGVPADIQEEDG-----------------------IQYKFEVYQK-SV---   186 
dhfr-sup:C   --------------------FSEFHDADAQNS-----------HSYCFKILER---R--   159 
dhfr-sup:D   --------------------------------SSRTVEDTNPALTHTYEVWQK----KA   162